TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.0100nMAssay Description:Binding affinity for delta opioid receptorMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.0230nMAssay Description:Binding affinity for delta opioid receptorMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.0250nMAssay Description:Effective concentration against stimulation of [35S]-GTP-gammaS, binding in CHO cells transfected with the human opioid receptor delta 1More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.140nMAssay Description:In vitro binding affinity towards opioid receptor mu 1More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.152nMAssay Description:In vitro binding affinity towards opioid receptor delta 1More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Inhibition of [3H]-DPDPE radioligand binding to rat opioid receptor delta 1 site from rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Agonistic activity at DRD3 receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(MOUSE)
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Binding affinity against mu opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.222nMAssay Description:In vitro binding affinity towards opioid receptor mu 1More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.240nMAssay Description:In vitro binding affinity towards opioid receptor delta 1More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.240nMAssay Description:Binding affinity for delta opioid receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Institutes Of Health
Curated by ChEMBL
National Institutes Of Health
Curated by ChEMBL
Affinity DataKi: 0.247nMAssay Description:In vitro inhibition of [3H]- 8-OH-DPAT binding to cloned cell line containing human 5-hydroxytryptamine 1A receptor by Panlabs assayMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.25nMAssay Description:In vitro binding affinity towards opioid receptor delta 1More data for this Ligand-Target Pair
TargetMu-type opioid receptor(MOUSE)
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.260nMAssay Description:Binding affinity against mu opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.260nMAssay Description:In vitro binding affinity towards opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:For competition binding experiments, 0.5 mg of the rat brain homogenates in 800 μL of binding buffer (2 mM MgCl2 in 50 mM Tris*HCl, pH=7.4) were...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Effective concentration against stimulation of [35S]-GTP-gammaS, binding in CHO cells transfected with the human opioid receptor delta 1More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.320nMAssay Description:Binding affinity for delta opioid receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Mus musculus (Mouse))
National Institutes Of Health
Curated by ChEMBL
National Institutes Of Health
Curated by ChEMBL
Affinity DataKi: 0.340nMAssay Description:Receptor-linked G protein activation at 5-hydroxytryptamine receptor was determined by measuring the stimulation of [35S]-GTP-gammaS, binding (Experi...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.360nMAssay Description:Binding affinity for delta opioid receptorMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.380nMAssay Description:Binding affinity for delta opioid receptorMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.384nMAssay Description:In vitro binding affinity towards opioid receptor delta 1More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.390nMAssay Description:Binding affinity for delta opioid receptorMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibition of [3H]-DPDPE radioligand binding to rat opioid receptor delta 1 site from rat brain membranesMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Inhibition of [3H]-DPDPE radioligand binding to rat opioid receptor delta 1 site from rat brain membranesMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Effective concentration against stimulation of [35S]-GTP-gammaS, binding in CHO cells transfected with the human opioid receptor delta 1More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.510nMAssay Description:In vitro binding affinity towards opioid receptor delta 1More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Institutes Of Health
Curated by ChEMBL
National Institutes Of Health
Curated by ChEMBL
Affinity DataKi: 0.515nMAssay Description:Compound was tested in vitro for the inhibition of [3H]- 8-OH-DPAT binding to cloned cell line containing human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.560nMAssay Description:Binding affinity for delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.580nMAssay Description:For competition binding experiments, 0.5 mg of the rat brain homogenates in 800 μL of binding buffer (2 mM MgCl2 in 50 mM Tris*HCl, pH=7.4) were...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.580nMAssay Description:Binding affinity for delta opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(MOUSE)
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.590nMAssay Description:Binding affinity against mu opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Institutes Of Health
Curated by ChEMBL
National Institutes Of Health
Curated by ChEMBL
Affinity DataKi: 0.590nMAssay Description:Compound was tested in vitro for the inhibition of [3H]- 8-OH-DPAT binding to cloned cell line containing human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Binding affinity for delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.631nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.654nMAssay Description:In vitro binding affinity towards opioid receptor mu 1More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.664nMAssay Description:In vitro binding affinity towards opioid receptor mu 1More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.720nMAssay Description:In vitro binding affinity towards opioid receptor delta 1More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Institutes Of Health
Curated by ChEMBL
National Institutes Of Health
Curated by ChEMBL
Affinity DataKi: 0.791nMAssay Description:In vitro inhibition of [3H]- 8-OH-DPAT binding to cloned cell line containing human 5-hydroxytryptamine 1A receptor (Experiment 2)More data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Antagonistic activity at rat DRD3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Antagonistic activity at human DRD3 receptor by filtration binding assayMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(MOUSE)
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Binding affinity against mu opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(MOUSE)
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.810nMAssay Description:Binding affinity against mu opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.860nMAssay Description:In vitro binding affinity towards opioid receptor delta 1More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.930nMAssay Description:In vitro binding affinity towards opioid receptor delta 1More data for this Ligand-Target Pair
TargetMu-type opioid receptor(MOUSE)
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity against mu opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Mus musculus (Mouse))
National Institutes Of Health
Curated by ChEMBL
National Institutes Of Health
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Receptor-linked G protein activation at 5-hydroxytryptamine receptor was determined by measuring the stimulation of [35S]-GTP-gammaS, bindingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:In vitro binding affinity towards opioid receptor mu 1More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Institutes Of Health
Curated by ChEMBL
National Institutes Of Health
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Compound was tested in vitro for the inhibition of [3H]- 8-OH-DPAT binding to cloned cell line containing human 5-hydroxytryptamine 1A receptor (Expe...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(MOUSE)
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Binding affinity against mu opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair