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Found 45 with Last Name = 'chen' and Initial = 'sf'
TargetAdenosine deaminase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50367032(COFORMYCIN)
Affinity DataKi:  0.100nMAssay Description:Compound was evaluated for the inhibition of adenosine deaminaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine deaminase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM22925((8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxol...)
Affinity DataKi:  0.100nMAssay Description:Compound was evaluated for the inhibition of adenosine deaminaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAdenosine deaminase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM28393((+)-EHNA | (2S,3R)-3-(6-amino-9H-purin-9-yl)nonan-...)
Affinity DataKi:  2nMAssay Description:Compound was evaluated for the inhibition of adenosine deaminaseMore data for this Ligand-Target Pair
TargetAdenosine deaminase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50404651(CHEMBL1555103)
Affinity DataKi:  80nMAssay Description:Compound was evaluated for the inhibition of adenosine deaminaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine deaminase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50404652(CHEMBL2114367)
Affinity DataKi:  122nMAssay Description:Compound was evaluated for the inhibition of adenosine deaminaseMore data for this Ligand-Target Pair
TargetAdenosine deaminase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50034908((2R,3S)-3-((R)-6-Amino-purin-9-yl)-nonan-2-ol | (2...)
Affinity DataKi:  500nMAssay Description:Compound was evaluated for the inhibition of adenosine deaminaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine deaminase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50034908((2R,3S)-3-((R)-6-Amino-purin-9-yl)-nonan-2-ol | (2...)
Affinity DataKi:  500nMAssay Description:Compound was evaluated for the inhibition of adenosine deaminaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine deaminase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50368778(CHEMBL610668)
Affinity DataKi:  1.41E+6nMAssay Description:Tested for inhibition against human plasma adenosine deaminase (ADA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine deaminase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14487((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...)
Affinity DataKi:  2.18E+6nMAssay Description:Tested for binding constant against adenosine deaminase (ADA2) in human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223090(3-(4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl...)
Affinity DataIC50:  14nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  23nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50095259((6,7-Dimethoxy-quinazolin-4-yl)-(3-ethynyl-phenyl)...)
Affinity DataIC50:  29nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataIC50:  39nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223084(CHEMBL251498 | N-(3-chloro-4-fluorophenyl)-6-(3-mo...)
Affinity DataIC50:  50nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223082(CHEMBL251700 | N-(3-chloro-4-fluorophenyl)-6-(3-(p...)
Affinity DataIC50:  89nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223095(4-(4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl...)
Affinity DataIC50:  95nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223092(5-(4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl...)
Affinity DataIC50:  114nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223085(CHEMBL249509 | N-(3-chloro-4-fluorophenyl)-6-ethyn...)
Affinity DataIC50:  127nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223093(4-(4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl...)
Affinity DataIC50:  152nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223088(4-(4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl...)
Affinity DataIC50:  186nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223086(4-(3-(6,7-dimethoxyquinazolin-4-ylamino)phenyl)-2-...)
Affinity DataIC50:  206nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223094(CHEMBL249511 | N-(3-chloro-4-fluorophenyl)-6-(2-ph...)
Affinity DataIC50:  331nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223091(4-(3-(6,7-dimethoxyquinazolin-4-ylamino)phenyl)but...)
Affinity DataIC50:  402nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223087(6,7-dimethoxy-N-(3-(2-phenylethynyl)phenyl)quinazo...)
Affinity DataIC50:  921nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167307(1-Benzo[b]thiophen-2-ylmethyl-5-iodo-1H-indole-2,3...)
Affinity DataIC50:  950nMAssay Description:In vitro inhibitory concentration against SARS coronavirus main protease (SARS CoV 3C-like protease)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167309(1-Benzo[b]thiophen-2-ylmethyl-7-bromo-1H-indole-2,...)
Affinity DataIC50:  980nMAssay Description:In vitro inhibitory concentration SARS coronavirus main protease (SARS CoV 3C-like protease) More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
National Chiayi University

Curated by ChEMBL
LigandPNGBDBM50418088(7-ETHYL-10-HYDROXY-CAMPTOTHECIN)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human topoisomerase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167307(1-Benzo[b]thiophen-2-ylmethyl-5-iodo-1H-indole-2,3...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibitory concentration against Chymotrypsin (serine protease)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223089(5-(3-(6,7-dimethoxyquinazolin-4-ylamino)phenyl)pen...)
Affinity DataIC50:  1.36E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223096(CHEMBL398963 | N-(3-chloro-4-fluorophenyl)-6-(2-(t...)
Affinity DataIC50:  1.64E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223083(3-(3-(6,7-dimethoxyquinazolin-4-ylamino)phenyl)pro...)
Affinity DataIC50:  1.64E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167306(1-Benzo[b]thiophen-2-ylmethyl-7-nitro-1H-indole-2,...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibitory concentration against SARS coronavirus main protease (SARS CoV 3C-like protease)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167311(1-Benzo[b]thiophen-2-ylmethyl-5-fluoro-1H-indole-2...)
Affinity DataIC50:  4.82E+3nMAssay Description:In vitro inhibitory concentration against SARS coronavirus main protease (SARS CoV 3C-like protease)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167314(1-(3,5-Dimethyl-isoxazol-4-ylmethyl)-2,3-dioxo-2,3...)
Affinity DataIC50:  7.20E+3nMAssay Description:In vitro inhibitory concentration against SARS coronavirus main protease (SARS CoV 3C-like protease)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
National Chiayi University

Curated by ChEMBL
LigandPNGBDBM50557284(CHEMBL4789468)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of human topoisomerase 1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167317(1-(2-Chloro-4-fluoro-benzyl)-5-iodo-1H-indole-2,3-...)
Affinity DataIC50:  9.40E+3nMAssay Description:In vitro inhibitory concentration against SARS coronavirus main protease (SARS CoV 3C-like protease)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167309(1-Benzo[b]thiophen-2-ylmethyl-7-bromo-1H-indole-2,...)
Affinity DataIC50:  1.04E+4nMAssay Description:In vitro inhibitory concentration against Chymotrypsin (serine protease)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167312(1-Benzo[b]thiophen-2-ylmethyl-4-chloro-1H-indole-2...)
Affinity DataIC50:  1.12E+4nMAssay Description:In vitro inhibitory concentration against SARS coronavirus main protease (SARS CoV 3C-like protease)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167308(5-(5-Iodo-2,3-dioxo-2,3-dihydro-indol-1-ylmethyl)-...)
Affinity DataIC50:  1.26E+4nMAssay Description:In vitro inhibitory concentration against SARS coronavirus main protease (SARS CoV 3C-like protease)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167313(1-Benzo[b]thiophen-2-ylmethyl-1H-indole-2,3-dione ...)
Affinity DataIC50:  1.31E+4nMAssay Description:In vitro inhibitory concentration against SARS coronavirus main protease (SARS CoV 3C-like protease)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167316(1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-5-iodo...)
Affinity DataIC50:  1.35E+4nMAssay Description:In vitro inhibitory concentration against SARS coronavirus main protease (SARS CoV 3C-like protease) at 20 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167315(5-Iodo-1-[5-(piperidine-1-carbonyl)-thiophen-2-ylm...)
Affinity DataIC50:  1.75E+4nMAssay Description:In vitro inhibitory concentration against SARS coronavirus main protease (SARS CoV 3C-like protease)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167310(1-((E)-3-Benzo[b]thiophen-2-yl-allyl)-5-iodo-1H-in...)
Affinity DataIC50:  2.35E+4nMAssay Description:In vitro inhibitory concentration against SARS coronavirus main protease (SARS CoV 3C-like protease)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
National Chiayi University

Curated by ChEMBL
LigandPNGBDBM50008923((S)-4-ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-...)
Affinity DataIC50:  6.29E+4nMAssay Description:Inhibition of human topoisomerase 1More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM14487((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...)
Affinity DataEC50:  4.00E+4nMAssay Description:Effective concentration required for cyclic AMP dependent inhibition of blood platelet aggregation for A2 receptor stimulationMore data for this Ligand-Target Pair