TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 0.110nMAssay Description:Displacement of [3H]-paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 0.121nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 0.130nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by PDSP Ki Database
Wake Forest University
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 0.220nMAssay Description:Displacement of [3H]-paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 0.230nMAssay Description:Affinity for the displacement of [3H]-paroxetine binding to serotonin transporter (SERT) in rat frontal cortex membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 0.320nMAssay Description:Displacement of [3H]-paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 0.370nMAssay Description:Affinity for the displacement of [3H]-paroxetine binding to serotonin transporter (SERT) in rat frontal cortex membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 0.380nMAssay Description:Affinity for the displacement of [3H]-paroxetine binding to serotonin transporter (SERT) in rat frontal cortex membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 0.390nMAssay Description:Displacement of [3H]-paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 0.394nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by PDSP Ki Database
Wake Forest University
Curated by PDSP Ki Database
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by PDSP Ki Database
Wake Forest University
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 0.470nMAssay Description:Affinity for the displacement of [3H]-paroxetine binding to serotonin transporter (SERT) in rat frontal cortex membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 0.570nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by PDSP Ki Database
Wake Forest University
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 0.620nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by PDSP Ki Database
Wake Forest University
Curated by PDSP Ki Database
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by PDSP Ki Database
Wake Forest University
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 0.820nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-dawley rat frontal cortex by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 0.820nMAssay Description:Displacement of [3H]-paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Wake Forest University School Of Medicine
Curated by ChEMBL
Wake Forest University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.870nMAssay Description:Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligandMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by PDSP Ki Database
Wake Forest University
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 1.06nMAssay Description:Affinity for the displacement of [3H]-paroxetine binding to serotonin transporter (SERT) in rat frontal cortex membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]-paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by PDSP Ki Database
Wake Forest University
Curated by PDSP Ki Database
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Wake Forest University School Of Medicine
Curated by ChEMBL
Wake Forest University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligandMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by PDSP Ki Database
Wake Forest University
Curated by PDSP Ki Database
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by PDSP Ki Database
Wake Forest University
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 1.68nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-dawley rat frontal cortex by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Wake Forest University
Curated by PDSP Ki Database
Wake Forest University
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]-paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 1.97nMAssay Description:Affinity for the displacement of [3H]-paroxetine binding to serotonin transporter (SERT) in rat frontal cortex membranesMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Wake Forest University
Curated by PDSP Ki Database
Wake Forest University
Curated by PDSP Ki Database
Affinity DataKi: 2.05nMAssay Description:Affinity for the displacement of [3H]-paroxetine binding to norepinephrine transporter (NET) in rat frontal cortex membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 2.08nMAssay Description:Affinity for the displacement of [3H]-paroxetine binding to serotonin transporter (SERT) in rat frontal cortex membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 2.24nMAssay Description:Affinity for the displacement of [3H]-paroxetine binding to serotonin transporter (SERT) in rat frontal cortex membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 2.27nMAssay Description:Affinity for the displacement of [3H]-paroxetine binding to serotonin transporter (SERT) in rat frontal cortex membranesMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Wake Forest University
Curated by PDSP Ki Database
Wake Forest University
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Ability to displace 0.4 nM [3H]-paroxetine binding to serotonin transporter in rat frontal cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Ability to displace 0.4 nM [3H]-paroxetine binding to serotonin transporter in rat frontal cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Wake Forest University School Of Medicine
Curated by ChEMBL
Wake Forest University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 2.45nMAssay Description:Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligandMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Ability to displace 0.4 nM [3H]paroxetine binding to serotonin transporter in rat frontal cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Ability to displace 0.4 nM [3H]-paroxetine binding to serotonin transporter in rat frontal cortexMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Wake Forest University School Of Medicine
Curated by ChEMBL
Wake Forest University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 2.53nMAssay Description:Compound tested for binding affinity towards sigma 1 receptor in quinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand.More data for this Ligand-Target Pair