Affinity DataIC50: 3.70nMAssay Description:Cells were seeded into 12-well tissue culture plates to reach 90% confluence at the time of assay. All cell types, aside from the HEK293-gfpPLD2 cell...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Cells were seeded into 12-well tissue culture plates to reach 90% confluence at the time of assay. All cell types, aside from the HEK293-gfpPLD2 cell...More data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Chosun University
Curated by ChEMBL
Chosun University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human 15-PGDH expressed in Escherichia coli using PGE2 as substrate and NAD+ as coenzyme assessed as formation of NADH by spectrophotom...More data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Chosun University
Curated by ChEMBL
Chosun University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human 15-PGDH expressed in Escherichia coli using PGE2 as substrate and NAD+ as coenzyme assessed as formation of NADH by spectrophotom...More data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Chosun University
Curated by ChEMBL
Chosun University
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of human 15-PGDH expressed in Escherichia coli using PGE2 as substrate and NAD+ as coenzyme assessed as formation of NADH by spectrophotom...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Cells were seeded into 12-well tissue culture plates to reach 90% confluence at the time of assay. All cell types, aside from the HEK293-gfpPLD2 cell...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Cells were seeded into 12-well tissue culture plates to reach 90% confluence at the time of assay. All cell types, aside from the HEK293-gfpPLD2 cell...More data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Chosun University
Curated by ChEMBL
Chosun University
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of human 15-PGDH expressed in Escherichia coli using PGE2 as substrate and NAD+ as coenzyme assessed as formation of NADH by spectrophotom...More data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Chosun University
Curated by ChEMBL
Chosun University
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of human 15-PGDH expressed in Escherichia coli using PGE2 as substrate and NAD+ as coenzyme assessed as formation of NADH by spectrophotom...More data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Chosun University
Curated by ChEMBL
Chosun University
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of human 15-PGDH expressed in Escherichia coli using PGE2 as substrate and NAD+ as coenzyme assessed as formation of NADH by spectrophotom...More data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Chosun University
Curated by ChEMBL
Chosun University
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of human 15-PGDH expressed in Escherichia coli using PGE2 as substrate and NAD+ as coenzyme assessed as formation of NADH by spectrophotom...More data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Chosun University
Curated by ChEMBL
Chosun University
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of human 15-PGDH expressed in Escherichia coli using PGE2 as substrate and NAD+ as coenzyme assessed as formation of NADH by spectrophotom...More data for this Ligand-Target Pair
Affinity DataIC50: 355nMAssay Description:Cells were seeded into 12-well tissue culture plates to reach 90% confluence at the time of assay. All cell types, aside from the HEK293-gfpPLD2 cell...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Cells were seeded into 12-well tissue culture plates to reach 90% confluence at the time of assay. All cell types, aside from the HEK293-gfpPLD2 cell...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:TP_TRANSPORTER: drug resistance (vincristine) in AML-2/D100 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:TP_TRANSPORTER: drug resistance (vincristine) in AML-2/D100 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:TP_TRANSPORTER: drug resistance (vincristine) in AML-2/D100 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:TP_TRANSPORTER: drug resistance (vincristine) in AML-2/D100 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:TP_TRANSPORTER: drug resistance (vincristine) in AML-2/D100 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:TP_TRANSPORTER: drug resistance (vincristine) in AML-2/D100 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Cells were seeded into 12-well tissue culture plates to reach 90% confluence at the time of assay. All cell types, aside from the HEK293-gfpPLD2 cell...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMpH: 7.5Assay Description:Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:TP_TRANSPORTER: drug resistance (vincristine) in AML-2/D100 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMpH: 7.5Assay Description:In a 96-black well plate, in a final reaction volume of 200 μL, the following components were combined on ice to yield final concentrations of 5...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMpH: 7.5Assay Description:Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Cells were seeded into 12-well tissue culture plates to reach 90% confluence at the time of assay. All cell types, aside from the HEK293-gfpPLD2 cell...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMpH: 7.5Assay Description:Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMpH: 7.5Assay Description:Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...More data for this Ligand-Target Pair
Affinity DataIC50: 2.95E+3nMpH: 7.5Assay Description:In a 96-black well plate, in a final reaction volume of 200 μL, the following components were combined on ice to yield final concentrations of 5...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:TP_TRANSPORTER: drug resistance (vincristine) in AML-2/D100 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMpH: 7.5Assay Description:Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:TP_TRANSPORTER: drug resistance (vincristine) in AML-2/D100 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMpH: 7.5Assay Description:Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMpH: 7.5Assay Description:Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMpH: 7.5Assay Description:In brief, 6 nM purified PldA was incubated with liposomes containing 90 μM 1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol), 10 μM...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMpH: 7.5Assay Description:Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMpH: 7.5Assay Description:Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Cells were seeded into 12-well tissue culture plates to reach 90% confluence at the time of assay. All cell types, aside from the HEK293-gfpPLD2 cell...More data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMpH: 7.5Assay Description:In a 96-black well plate, in a final reaction volume of 200 μL, the following components were combined on ice to yield final concentrations of 5...More data for this Ligand-Target Pair
Affinity DataIC50: 5.80E+3nMpH: 7.5Assay Description:Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10E+3nMAssay Description:Cells were seeded into 12-well tissue culture plates to reach 90% confluence at the time of assay. All cell types, aside from the HEK293-gfpPLD2 cell...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10E+3nMpH: 7.5Assay Description:Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...More data for this Ligand-Target Pair
Affinity DataIC50: 6.20E+3nMpH: 7.5Assay Description:Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+3nMAssay Description:TP_TRANSPORTER: drug resistance (vincristine) in AML-2/D100 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.40E+3nMpH: 7.5Assay Description:In a 96-black well plate, in a final reaction volume of 200 μL, the following components were combined on ice to yield final concentrations of 5...More data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+3nMAssay Description:Cells were seeded into 12-well tissue culture plates to reach 90% confluence at the time of assay. All cell types, aside from the HEK293-gfpPLD2 cell...More data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+3nMpH: 7.5Assay Description:In brief, 6 nM purified PldA was incubated with liposomes containing 90 μM 1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol), 10 μM...More data for this Ligand-Target Pair
Affinity DataIC50: 7.10E+3nMpH: 7.5Assay Description:Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...More data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMpH: 7.5Assay Description:In brief, 6 nM purified PldA was incubated with liposomes containing 90 μM 1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol), 10 μM...More data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+3nMpH: 7.5Assay Description:In a 96-black well plate, in a final reaction volume of 200 μL, the following components were combined on ice to yield final concentrations of 5...More data for this Ligand-Target Pair