Affinity DataKi: 0.100nMAssay Description:Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular cal...More data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular cal...More data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular cal...More data for this Ligand-Target Pair
Affinity DataKi: 0.190nM ΔG°: -54.9kJ/mole IC50: 0.5nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular cal...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Inhibition of of human recombinant His6-tagged B-Raf V600E mutant expressed in baculovirus infected cells co-expresing CDC37 in presence of [gamma33P...More data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular cal...More data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular cal...More data for this Ligand-Target Pair
Affinity DataKi: 0.280nM ΔG°: -54.0kJ/mole IC50: 0.300nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Displacement of [3H]CP55940 from human cannabinoid CB1 receptor expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular cal...More data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular cal...More data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Displacement of [3H]CP55940 from human cannabinoid CB2 receptor expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular cal...More data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.530nM ΔG°: -52.4kJ/mole IC50: 3.5nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular cal...More data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]CP55940 from human cannabinoid CB2 receptor expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.891nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.891nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.933nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular cal...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Displacement of [3H]CP55940 from human cannabinoid CB1 receptor expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular cal...More data for this Ligand-Target Pair
Affinity DataKi: 1.27nM ΔG°: -50.3kJ/mole IC50: 1.90nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition of of human recombinant His6-tagged B-Raf V600E mutant expressed in baculovirus infected cells co-expresing CDC37 in presence of [gamma33P...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.58nMAssay Description:Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular cal...More data for this Ligand-Target Pair
Affinity DataKi: 1.58nMAssay Description:Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular cal...More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair