BindingDB PrimarySearch_ki

Found 444 with Last Name = 'clarke' and Initial = 'wj'

Neuropeptide Y receptor type 1(Homo sapiens (Human))
TBA

Curated by ChEMBL

PNG

BDBM50386376(CHEMBL2046865)

Ki: 15nMAssay Description:Displacement of [125I]peptideYY from NPY1 receptor in human SK-N-MC cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid

Details Article PubMed

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM610453(2-Phenyl-N-(4-(2,2,2-trifluoroethoxy)pyridin-3-yl)...)

IC50: 0.0900nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM50613245(CHEMBL5266553)

IC50: 0.100nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM50613418(CHEMBL5268185)

IC50: 0.170nMAssay Description:Inhibition of GST tagged GSK-3alpha (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM610483(2-Cyclopropyl-N-(4-(4,4-difluoropiperidin-1-yl)pyr...)

IC50: 0.180nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM610462(N-(4-Morpholinopyridin-3-yl)-2-phenylimidazo[1,2-b...)

IC50: 0.210nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM610461(N-(4-(4,4-Difluoropiperidin-1-yl)pyridin-3-yl)-2-p...)

IC50: 0.220nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM610477(N-(4-Morpholinopyridin-3-yl)-2-(4-(trifluoromethyl...)

IC50: 0.230nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM610458(2-Phenyl-N-(4-(piperidin-1-yl)pyridin-3-yl)imidazo...)

IC50: 0.240nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM50613417(CHEMBL5290300)

IC50: 0.280nMAssay Description:Inhibition of GST tagged GSK-3alpha (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM610469((S)�N-(4-(3-Methylmorpholino)pyridin-3-yl)-2-pheny...)

IC50: 0.320nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM50613415(CHEMBL5273872)

IC50: 0.340nMAssay Description:Inhibition of GST tagged GSK-3alpha (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM50613246(CHEMBL5316226)

IC50: 0.340nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM610463(BDBM610464 | BDBM610465 | N-(4-(2-Methylmorpholino...)

IC50: 0.350nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid PDB

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM610476(2-(2-Methoxyphenyl)-N-(4-(2-methylmorpholino)pyrid...)

IC50: 0.380nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM610454(N-(4-(Methylsulfonyl)pyridin-3-yl)-2-phenylimidazo...)

IC50: 0.400nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM610452(N-(4-Isopropoxypyridin-3-yl)-2-phenylimidazo[1,2-b...)

IC50: 0.410nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM610482(2-Cyclopropyl-N-(4-(4-fluorophenyl)pyridin-3-yl)im...)

IC50: 0.440nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM50613407(CHEMBL5269649)

IC50: 0.450nMAssay Description:Inhibition of GST tagged GSK-3alpha (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM610478(N-(4-(2-Methylmorpholino)pyridin-3-yl)-2-(4-(trifl...)

IC50: 0.570nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM50613413(CHEMBL5265990)

IC50: 0.660nMAssay Description:Inhibition of GST tagged GSK-3alpha (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM50613402(CHEMBL5270885)

IC50: 0.740nMAssay Description:Inhibition of GST tagged GSK-3alpha (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM610451(N-(4-Methylpyridin-3-yl)-2-phenylimidazo[1,2-b]pyr...)

IC50: 0.800nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM610484(2-Cyclopropyl-N-(4-(2-methylmorpholino)pyridin-3-y...)

IC50: 0.800nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 beta(Homo sapiens (Human))TBA

PNG

BDBM50613418(CHEMBL5268185)

IC50: 0.870nMAssay Description:Inhibition of GST tagged GSK-3beta (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM50613414(CHEMBL5280241)

IC50: 0.880nMAssay Description:Inhibition of GST tagged GSK-3alpha (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 beta(Homo sapiens (Human))TBA

PNG

BDBM50613402(CHEMBL5270885)

IC50: 1nMAssay Description:Inhibition of GST tagged GSK-3beta (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM610468((R)�N-(4-(3-Methylmorpholino)pyridin-3-yl)-2-pheny...)

IC50: 1nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM50613401(CHEMBL5284458)

IC50: 1.10nMAssay Description:Inhibition of GST tagged GSK-3alpha (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM50613411(CHEMBL5287898)

IC50: 1.10nMAssay Description:Inhibition of GST tagged GSK-3alpha (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM610456(N-(4-(4-Fluorophenyl)pyridin-3-yl)-2-phenylimidazo...)

IC50: 1.10nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM610455(2-Phenyl-N-(4-phenylpyridin-3-yl)imidazo[1,2-b]pyr...)

IC50: 1.10nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM50613419(CHEMBL5281592)

IC50: 1.20nMAssay Description:Inhibition of GST tagged GSK-3alpha (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 beta(Homo sapiens (Human))TBA

PNG

BDBM50613417(CHEMBL5290300)

IC50: 1.20nMAssay Description:Inhibition of GST tagged GSK-3beta (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM610496(3-((Cyclopropylmethyl)amino)-N-(4-(4,4-difluoropip...)

IC50: 1.40nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM50613423(CHEMBL5283654)

IC50: 1.40nMAssay Description:Inhibition of GST tagged GSK-3alpha (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM610497(3-((Cyclopropylmethyl)amino)-N-(4-morpholinopyridi...)

IC50: 1.40nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM610498(3-((Cyclopropylmethyl)amino)-N-(4-(2-methylmorphol...)

IC50: 1.60nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM50613393(CHEMBL5288565)

IC50: 1.70nMAssay Description:Inhibition of GST tagged GSK-3alpha (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM50613403(CHEMBL5271618)

IC50: 1.80nMAssay Description:Inhibition of GST tagged GSK-3alpha (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 beta(Homo sapiens (Human))TBA

PNG

BDBM50613415(CHEMBL5273872)

IC50: 1.90nMAssay Description:Inhibition of GST tagged GSK-3beta (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM50613409(CHEMBL5272425)

IC50: 1.90nMAssay Description:Inhibition of GST tagged GSK-3alpha (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 beta(Homo sapiens (Human))TBA

PNG

BDBM50613423(CHEMBL5283654)

IC50: 1.90nMAssay Description:Inhibition of GST tagged GSK-3beta (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Glycogen synthase kinase-3 beta(Homo sapiens (Human))TBA

PNG

BDBM50613413(CHEMBL5265990)

IC50: 2nMAssay Description:Inhibition of GST tagged GSK-3beta (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Glycogen synthase kinase-3 beta(Homo sapiens (Human))TBA

PNG

BDBM50613244(CHEMBL5291119)

IC50: 2nMAssay Description:Inhibition of GSK3-beta (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM50613394(CHEMBL5278465)

IC50: 2nMAssay Description:Inhibition of GST tagged GSK-3alpha (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM610495(3-((Cyclopropylmethyl)amino)-N-(4-phenylpyridin-3-...)

IC50: 2nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid PDB

Glycogen synthase kinase-3 beta(Homo sapiens (Human))TBA

PNG

BDBM50613425(CHEMBL5284549)

IC50: 2nMAssay Description:Inhibition of human GSK-3beta using peptide substrate after 45 mins in presence of ATP by Kinase-Glo luminescence assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Glycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA

PNG

BDBM50613416(CHEMBL5280368)

IC50: 2.10nMAssay Description:Inhibition of GST tagged GSK-3alpha (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Glycogen synthase kinase-3 beta(Homo sapiens (Human))TBA

PNG

BDBM50613407(CHEMBL5269649)

IC50: 2.10nMAssay Description:Inhibition of GST tagged GSK-3beta (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Displayed 1 to 50 (of 444 total ) | Next | Last >>

Filter my 444 hits

Targets 61▿
- Glycogen synthase kinase-3 beta 72
- Glycogen synthase kinase-3 alpha 66
- Inhibitor of nuclear factor kappa-B kinase subunit beta 53
- Inhibitor of nuclear factor kappa-B kinase subunit alpha 50
- Neuropeptide Y receptor type 1 26
- Microtubule-associated protein tau 12
- Non-receptor tyrosine-protein kinase TYK2 8
- Interleukin-1 receptor-associated kinase 4 5
- Tyrosine-protein kinase Lck 5
- Tyrosine-protein kinase BTK 5
- Insulin-like growth factor 1 receptor 5
- Serine/threonine-protein kinase pim-1 5
- Protein kinase C theta type 5
- Tyrosine-protein kinase SYK 5
- Cyclin-dependent kinase 2 5
- Mast/stem cell growth factor receptor Kit 5
- Tyrosine-protein kinase JAK2 5
- Ribosomal protein S6 kinase alpha-1 5
- MAP kinase-activated protein kinase 2 5
- Platelet-derived growth factor receptor beta 5
- Mitogen-activated protein kinase 14 5
- Aurora kinase B 5
- Casein kinase II subunit alpha' 5
- Platelet-derived growth factor receptor alpha/beta 4
- Tyrosine-protein kinase ABL1 4
- Tyrosine-protein kinase JAK1 4
- Aurora kinase A 4
- Mitogen-activated protein kinase 8 4
- Golgi-associated PDZ and coiled-coil motif-containing protein 3
- Tyrosine-protein kinase JAK3 3
- Rho-associated protein kinase 2 3
- Rho-associated protein kinase 1 3
- High affinity nerve growth factor receptor 3
- Macrophage colony-stimulating factor 1 receptor 3
- BDNF/NT-3 growth factors receptor 3
- Tyrosine-protein kinase Srms 3
- Serine/threonine-protein kinase 33 2
- Cytoplasmic tyrosine-protein kinase BMX 2
- Activated CDC42 kinase 1 2
- Interleukin-1 receptor-associated kinase 1 2
- Casein kinase I isoform delta 2
- Tyrosine-protein kinase ZAP-70 2
- Tyrosine-protein kinase ITK/TSK 2
- Tyrosine-protein kinase CSK 2
- AP2-associated protein kinase 1 1
- Tyrosine-protein kinase Tec 1
- Tyrosine-protein kinase Fyn 1
- MAP/microtubule affinity-regulating kinase 3 1
- Tyrosine-protein kinase Lyn 1
- Cyclin-dependent kinase 5 1
- Potassium voltage-gated channel subfamily H member 2 1
- Serine/threonine-protein kinase MARK1 1
- Serine/threonine-protein kinase MARK2 1
- Cytochrome P450 4B1 1
- MAP/microtubule affinity-regulating kinase 4 1
- TRAF2 and NCK-interacting protein kinase 1
- Nuclear receptor subfamily 4 group A member 3 1
- Tyrosine-protein kinase TXK 1
- Tau-tubulin kinase 1 1
- Tau-tubulin kinase 2 1
- Casein kinase II subunit alpha 1
- ...
Publications 3▿
- Bioorg Med Chem Lett 17: 4284-9 (2007) 100
- Bioorg Med Chem Lett 23: 3814-7 (2013) 14
- ACS Med Chem Lett 3: 222-226 (2012) 12
Institutions 3▿
- Bristol-Myers Squibb 100
- Bristol-Myers Squibb Research And Development 14
- TBA 12
Affinity: 0.090 to 1.0E+5 nM▿
- Ki 1
- IC50 443
- Affinity ≤ nM
Xtal structures: 4
Docked structures: 0
Catalog Cmpds: 4