Affinity DataIC50: 0.5nMAssay Description:Inhibition of human erythrocyte AChE by Ellman's reactionMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen Pharmaceutica
Curated by ChEMBL
Janssen Pharmaceutica
Curated by ChEMBL
Affinity DataIC50: 0.646nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected Sf9 cells using [3H]cAMP as substrate after 60 mins by TopCount scintillation ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human erythrocyte AChE by Ellman's reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of horse serum BChE by Ellman's reactionMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Instituto De Qui£?Mica Medica-Csic
Curated by ChEMBL
Instituto De Qui£?Mica Medica-Csic
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant GSK3beta using prephosphorylated polypeptide substrate after 30 mins by Glow-type luminescence assay in presence of 1...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of horse serum BChE by Ellman's reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human erythrocyte AChE by Ellman's reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human serum BChE by Ellman's reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Inhibition of horse serum BChE by Ellman's reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of horse serum BChE by Ellman's reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of BuChE in horse serum using butyrylthiocholine as substrate by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of equine serum BuChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of horse serum BuChE using butyrylthiocholine as substrate by UV spectroscopic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of horse serum BChE by Ellman's reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of BuChE in horse serum by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human serum BChE by Ellman's reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of horse serum BChE by Ellman's reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of horse serum BChE by Ellman's reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human BuChE in serumMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human serum BChE by Ellman's reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of AChE in bovine erythrocyte by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of AChE in bovine erythrocytes using acetylthiocholine as substrate by Ellman methodMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Instituto De Qui£?Mica Medica-Csic
Curated by ChEMBL
Instituto De Qui£?Mica Medica-Csic
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant GSK3beta using prephosphorylated polypeptide substrate after 30 mins by Glow-type luminescence assay in presence of 1...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen Pharmaceutica
Curated by ChEMBL
Janssen Pharmaceutica
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected Sf9 cells using [3H]cAMP as substrate after 60 mins by TopCount scintillation ...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of BuChE in horse serum by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of horse serum BChE by Ellman's reactionMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen Pharmaceutica
Curated by ChEMBL
Janssen Pharmaceutica
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected Sf9 cells using [3H]cAMP as substrate after 60 mins by TopCount scintillation ...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of human serum BChE by Ellman's reactionMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen Pharmaceutica
Curated by ChEMBL
Janssen Pharmaceutica
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected Sf9 cells using [3H]cAMP as substrate after 60 mins by TopCount scintillation ...More data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of horse serum BChE by Ellman's reactionMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen Pharmaceutica
Curated by ChEMBL
Janssen Pharmaceutica
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected Sf9 cells using [3H]cAMP as substrate after 60 mins by TopCount scintillation ...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen Pharmaceutica
Curated by ChEMBL
Janssen Pharmaceutica
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected Sf9 cells using [3H]cAMP as substrate after 60 mins by TopCount scintillation ...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of human BuChE in serumMore data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's reactionMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of human recombinant PDE4D3 assessed after 60 mins by IMAP fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's reactionMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen Pharmaceutica
Curated by ChEMBL
Janssen Pharmaceutica
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected Sf9 cells using [3H]cAMP as substrate after 60 mins by TopCount scintillation ...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's reactionMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's reactionMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen Pharmaceutica
Curated by ChEMBL
Janssen Pharmaceutica
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Inhibition of rat recombinant PDE10A expressed in Sf9 cells using [3H]cAMP substrate incubated for 60 mins by topcount scintillation counting methodMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Inhibition of human recombinant PDE4B2 assessed after 60 mins by IMAP fluorescence polarization assayMore data for this Ligand-Target Pair