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Found 2295 with Last Name = 'cui' and Initial = 'y'
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
The University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50010704(CHEMBL216640 | Dyn A(1-11)-NH2 | Dynorphin A analo...)
Affinity DataKi:  0.570nMAssay Description:Displacement of [3H]Diprenorphine from rat kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
The University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50297345((5S,8S,13R,Z)-13-((S)-2-amino-3-(4-hydroxyphenyl)p...)
Affinity DataKi:  0.840nMAssay Description:Displacement of [3H]Diprenorphine from rat kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50057015(CHEMBL3331617)
Affinity DataKi:  0.900nMAssay Description:Mixed-type inhibition of bovine xanthine oxidase assessed as inhibition of uric acid formation by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311944(US10166214, Example 80 | US10675268, Example 80 | ...)
Affinity DataKi:  1.20nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311944(US10166214, Example 80 | US10675268, Example 80 | ...)
Affinity DataKi:  1.20nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311944(US10166214, Example 80 | US10675268, Example 80 | ...)
Affinity DataKi:  1.20nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Rattus norvegicus (rat))
The University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50010704(CHEMBL216640 | Dyn A(1-11)-NH2 | Dynorphin A analo...)
Affinity DataKi:  1.85nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50057015(CHEMBL3331617)
Affinity DataKi:  2.30nMAssay Description:Mixed-type inhibition of bovine xanthine oxidase assessed as inhibition of uric acid formation by secondary Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
The University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50297345((5S,8S,13R,Z)-13-((S)-2-amino-3-(4-hydroxyphenyl)p...)
Affinity DataKi:  2.33nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
The University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50297347((2S,5S,8S,13S,Z)-13-((S)-2-(2-(2-((S)-2-amino-3-(4...)
Affinity DataKi:  2.46nMAssay Description:Displacement of [3H]Diprenorphine from rat kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311888(US10166214, Example 24 | US10675268, Example 24 | ...)
Affinity DataKi:  2.90nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311888(US10166214, Example 24 | US10675268, Example 24 | ...)
Affinity DataKi:  2.90nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311888(US10166214, Example 24 | US10675268, Example 24 | ...)
Affinity DataKi:  2.90nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311990(US10166214, Example 126 | US10675268, Example 126 ...)
Affinity DataKi:  3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311990(US10166214, Example 126 | US10675268, Example 126 ...)
Affinity DataKi:  3nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311990(US10166214, Example 126 | US10675268, Example 126 ...)
Affinity DataKi:  3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311971(US10166214, Example 107 | US10675268, Example 107 ...)
Affinity DataKi:  3.40nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311971(US10166214, Example 107 | US10675268, Example 107 ...)
Affinity DataKi:  3.40nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311971(US10166214, Example 107 | US10675268, Example 107 ...)
Affinity DataKi:  3.40nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311957(US10166214, Example 93 | US10675268, Example 93 | ...)
Affinity DataKi:  3.60nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311957(US10166214, Example 93 | US10675268, Example 93 | ...)
Affinity DataKi:  3.60nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311957(US10166214, Example 93 | US10675268, Example 93 | ...)
Affinity DataKi:  3.60nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM50081058(CHEMBL3421842 | US10166214, Example 22 | US1067526...)
Affinity DataKi:  3.70nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM50081058(CHEMBL3421842 | US10166214, Example 22 | US1067526...)
Affinity DataKi:  3.70nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM50081058(CHEMBL3421842 | US10166214, Example 22 | US1067526...)
Affinity DataKi:  3.70nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM50081055(CHEMBL3421843 | US10166214, Example 49 | US1067526...)
Affinity DataKi:  4.5nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM50081055(CHEMBL3421843 | US10166214, Example 49 | US1067526...)
Affinity DataKi:  4.5nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM50081055(CHEMBL3421843 | US10166214, Example 49 | US1067526...)
Affinity DataKi:  4.5nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDelta-type opioid receptor(MOUSE)
The University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50010704(CHEMBL216640 | Dyn A(1-11)-NH2 | Dynorphin A analo...)
Affinity DataKi:  6.18nMAssay Description:Displacement of [3H]DPDPE from mouse delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
The University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50271443(CHEMBL522293 | Tyr-Pro-Phe-Phe-OCH2OH)
Affinity DataKi:  6.34nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311992(US10166214, Example 128 | US10675268, Example 128 ...)
Affinity DataKi:  7.60nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311992(US10166214, Example 128 | US10675268, Example 128 ...)
Affinity DataKi:  7.60nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311992(US10166214, Example 128 | US10675268, Example 128 ...)
Affinity DataKi:  7.60nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Rattus norvegicus (rat))
The University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50139013((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataKi:  8.23nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
The University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50292208(1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyr...)
Affinity DataKi:  8.23nMAssay Description:Inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 of rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
The University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50163909(CHEMBL361922 | Tyr-Pro-Phe-Phe-OCH3 | Tyr-Pro-Phe-...)
Affinity DataKi:  9.07nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
The University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50297345((5S,8S,13R,Z)-13-((S)-2-amino-3-(4-hydroxyphenyl)p...)
Affinity DataKi:  9.30nMAssay Description:Displacement of [3H]DPDPE from mouse delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
The University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50163913(CHEMBL180777 | Tyr-Pro-Phe-Phe-NHNH2)
Affinity DataKi:  9.35nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311885(US10166214, Example 21 | US10675268, Example 21 | ...)
Affinity DataKi:  10.8nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311885(US10166214, Example 21 | US10675268, Example 21 | ...)
Affinity DataKi:  10.8nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311885(US10166214, Example 21 | US10675268, Example 21 | ...)
Affinity DataKi:  10.8nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
The University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50297347((2S,5S,8S,13S,Z)-13-((S)-2-(2-(2-((S)-2-amino-3-(4...)
Affinity DataKi:  10.9nMAssay Description:Displacement of [3H]Diprenorphine from rat kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
The University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50271441(CHEMBL505502 | Tyr-Pro-Phe-Phe-OCH2CH3)
Affinity DataKi:  15.0nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311958(US10166214, Example 94 | US10675268, Example 94 | ...)
Affinity DataKi:  15.9nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311958(US10166214, Example 94 | US10675268, Example 94 | ...)
Affinity DataKi:  15.9nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311958(US10166214, Example 94 | US10675268, Example 94 | ...)
Affinity DataKi:  15.9nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Rattus norvegicus (rat))
The University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50271439(CHEMBL453689 | Tyr-Pro-Phe-Phe-NHCH3)
Affinity DataKi:  29.2nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM312012(US10166214, Example 148 | US10675268, Example 148 ...)
Affinity DataKi:  32.3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM312012(US10166214, Example 148 | US10675268, Example 148 ...)
Affinity DataKi:  32.3nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM312012(US10166214, Example 148 | US10675268, Example 148 ...)
Affinity DataKi:  32.3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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