Found 113 with Last Name = 'demizu' and Initial = 'y' 
Affinity DataIC50: 0.0900nMAssay Description:Antagonist activity at ERalpha (unknown origin) transfected in 17beta-estradiol induced-HEK293 cells assessed as inhibition of estradiol-mediated pro...More data for this Ligand-Target Pair
Affinity DataIC50: 0.470nMAssay Description:Displacement of Fluormone ES2 from human recombinant full length untagged-ERalpha by fluorescence polarization competition binding assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 0.680nMAssay Description:Antagonist activity at ERalpha (unknown origin) transfected in 17beta-estradiol induced-HEK293 cells assessed as inhibition of estradiol-mediated pro...More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of estrogen receptor alpha (unknown origin)-SRC1 coactivator interaction incubated for 1 hr by receptor cofactor assay system based methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Displacement of Fluormone ES2 from human recombinant full length untagged-ERalpha by fluorescence polarization competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme in Hog plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibition of ERalpha (unknown origin) by fluorescence polarization-based competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibition of ERalpha (unknown origin) by fluorescence polarization-based competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of ERalpha (unknown origin) by fluorescence polarization-based competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Antagonist activity at ERalpha (unknown origin) expressed in human MCF7 cells assessed as inhibition of E2-induced response by dual luciferase report...More data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Inhibition of ERalpha (unknown origin) by fluorescence polarization-based competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:Displacement of Fluormone ES2 from human recombinant full length untagged-ERalpha by fluorescence polarization competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30nMAssay Description:Displacement of Fluormone ES2 from full length recombinant human untagged ERalpha expressed in Sf insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Displacement of Fluormone ES2 from human recombinant full length untagged-ERalpha by fluorescence polarization competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of ERalpha (unknown origin) by fluorescence polarization-based competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of estrogen receptor alpha (unknown origin)-SRC1 coactivator interaction incubated for 1 hr by receptor cofactor assay system based methodMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of ERalpha (unknown origin) by fluorescence polarization-based competition binding assayMore data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
National Institute Of Health Sciences
Curated by ChEMBL
National Institute Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human HPGDSMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Displacement of Fluormone ES2 from human recombinant full length untagged-ERalpha by fluorescence polarization competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Antagonist activity at estrogen receptor in mouse GT1-7 cells harboring beta-galactosidase reporter gene assessed as reduction in 17beta-estradiol in...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of estrogen receptor alpha (unknown origin)-SRC1 coactivator interaction incubated for 1 hr by receptor cofactor assay system based methodMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Displacement of Fluormone ES2 from human recombinant full length untagged-ERalpha by fluorescence polarization competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Displacement of Fluormone ES2 from human recombinant full length untagged-ERalpha by fluorescence polarization competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of ERalpha (unknown origin) by fluorescence polarization-based competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Displacement of Fluormone ES2 from human recombinant full length untagged-ERalpha by fluorescence polarization competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Antagonist activity at CMX-GAL4N fused human ERalpha expressed in HEK293 cells assessed as reduction in E2 induced response by luciferase reporter ge...More data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
National Institute Of Health Sciences
Curated by ChEMBL
National Institute Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human HPGDS expressed in Escherichia coli BL21 (DE3) measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
National Institute Of Health Sciences
Curated by ChEMBL
National Institute Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Binding affinity to recombinant human H-PGDS incubated for 1 hrs by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
National Institute Of Health Sciences
Curated by ChEMBL
National Institute Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of recombinant human HPGDS using [14C]-PGH2 as substrate preincubated for 1 min in presence of MgCl2 followed by substrate addition and me...More data for this Ligand-Target Pair
Affinity DataIC50: 94nMAssay Description:Inhibition of estrogen receptor alpha (unknown origin)-SRC1 coactivator interaction incubated for 1 hr by receptor cofactor assay system based methodMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of estrogen receptor alpha (unknown origin)-SRC1 coactivator interaction incubated for 1 hr by receptor cofactor assay system based methodMore data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
National Institute Of Health Sciences
Curated by ChEMBL
National Institute Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 117nMAssay Description:Binding affinity to recombinant human H-PGDS incubated for 1 hrs by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
National Institute Of Health Sciences
Curated by ChEMBL
National Institute Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 124nMAssay Description:Binding affinity to recombinant human H-PGDS incubated for 1 hrs by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
National Institute Of Health Sciences
Curated by ChEMBL
National Institute Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 134nMAssay Description:Binding affinity to recombinant human H-PGDS incubated for 1 hrs by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 134nMAssay Description:Antagonist activity at CMX-GAL4N fused human ERalpha expressed in HEK293 cells assessed as reduction in E2 induced response by luciferase reporter ge...More data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
National Institute Of Health Sciences
Curated by ChEMBL
National Institute Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of H-PGDS (unknown origin) using fluorescent probe by competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 151nMAssay Description:Inhibition of ERalpha (unknown origin) by fluorescence polarization-based competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 154nMAssay Description:Antagonist activity at CMX-GAL4N fused human ERalpha expressed in HEK293 cells assessed as reduction in E2 induced response by luciferase reporter ge...More data for this Ligand-Target Pair
Affinity DataIC50: 158nMAssay Description:Antagonist activity at CMX-GAL4N fused human ERalpha expressed in HEK293 cells assessed as reduction in E2 induced response by luciferase reporter ge...More data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
National Institute Of Health Sciences
Curated by ChEMBL
National Institute Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of H-PGDS (unknown origin) using fluorescent probe by competition binding assayMore data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
National Institute Of Health Sciences
Curated by ChEMBL
National Institute Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of H-PGDS (unknown origin) using fluorescent probe by competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 195nMAssay Description:Displacement of Fluormone ES2 from full length recombinant human untagged ERalpha expressed in Sf insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
National Institute Of Health Sciences
Curated by ChEMBL
National Institute Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 196nMAssay Description:Binding affinity to recombinant human H-PGDS incubated for 1 hrs by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of ERalpha (unknown origin) by fluorescence polarization-based competition binding assayMore data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
National Institute Of Health Sciences
Curated by ChEMBL
National Institute Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 211nMAssay Description:Binding affinity to recombinant human H-PGDS incubated for 1 hrs by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 225nMAssay Description:Antagonist activity at CMX-GAL4N fused human ERalpha expressed in HEK293 cells assessed as reduction in E2 induced response by luciferase reporter ge...More data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
National Institute Of Health Sciences
Curated by ChEMBL
National Institute Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 266nMAssay Description:Inhibition of recombinant human HPGDS expressed in Escherichia coli BL21 (DE3) measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 271nMAssay Description:Antagonist activity at CMX-GAL4N fused human ERalpha expressed in HEK293 cells assessed as reduction in E2 induced response by luciferase reporter ge...More data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
National Institute Of Health Sciences
Curated by ChEMBL
National Institute Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Binding affinity to recombinant human HPGDS expressed in Escherichia coli BL21 (DE3) measured after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
National Institute Of Health Sciences
Curated by ChEMBL
National Institute Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Binding affinity to recombinant human HPGDS expressed in Escherichia coli BL21 (DE3) measured after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
