TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb R & D
Curated by ChEMBL
Bristol-Myers Squibb R & D
Curated by ChEMBL
Affinity DataKi: 0.0100nMAssay Description:Antagonist activity at human CGRP receptorMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb R & D
Curated by ChEMBL
Bristol-Myers Squibb R & D
Curated by ChEMBL
Affinity DataKi: 0.0100nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb R & D
Curated by ChEMBL
Bristol-Myers Squibb R & D
Curated by ChEMBL
Affinity DataKi: 0.0100nMAssay Description:Displacement of [I125]CGRP from human CGRP receptor in SK-N-MC cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb R & D
Curated by ChEMBL
Bristol-Myers Squibb R & D
Curated by ChEMBL
Affinity DataKi: 0.0128nMAssay Description:Displacement of [I125]CGRP from human CGRP receptor in SK-N-MC cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb R & D
Curated by ChEMBL
Bristol-Myers Squibb R & D
Curated by ChEMBL
Affinity DataKi: 0.0130nMAssay Description:Antagonist activity at human CGRP receptorMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb R & D
Curated by ChEMBL
Bristol-Myers Squibb R & D
Curated by ChEMBL
Affinity DataKi: 0.0210nMAssay Description:Antagonist activity at human CGRP receptorMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb R & D
Curated by ChEMBL
Bristol-Myers Squibb R & D
Curated by ChEMBL
Affinity DataKi: 0.0230nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb R & D
Curated by ChEMBL
Bristol-Myers Squibb R & D
Curated by ChEMBL
Affinity DataKi: 0.0270nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cells after 2 hrs by gamma scintillation counter analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.0600nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb R & D
Curated by ChEMBL
Bristol-Myers Squibb R & D
Curated by ChEMBL
Affinity DataKi: 0.0660nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cells after 2 hrs by gamma scintillation counter analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb R & D
Curated by ChEMBL
Bristol-Myers Squibb R & D
Curated by ChEMBL
Affinity DataKi: 0.0700nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb R & D
Curated by ChEMBL
Bristol-Myers Squibb R & D
Curated by ChEMBL
Affinity DataKi: 0.0710nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb R & D
Curated by ChEMBL
Bristol-Myers Squibb R & D
Curated by ChEMBL
Affinity DataKi: 0.0810nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cells after 2 hrs by gamma scintillation counter analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.180nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb R & D
Curated by ChEMBL
Bristol-Myers Squibb R & D
Curated by ChEMBL
Affinity DataKi: 0.260nMAssay Description:Displacement of [I125]CGRP from human CGRP receptor in SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Displacement of [3H]-pyrilamine from human histamine H1 receptor expressed in recombinant CHOK1 cells after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4-(methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK1...More data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.520nMAssay Description:Displacement of 3H-LP-927443 from AAK1 in C57BL6 mouse brain homogenate assessed as inhibition constant incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair