Affinity DataKi: 0.480nMAssay Description:In vitro binding affinity towards cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.510nMAssay Description:Binding affinity against human Alpha-1a adrenergic receptor was evaluated by cloned receptor binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.990nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:In vitro binding affinity towards cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:In vitro binding affinity towards cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1B adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Binding affinity against human Alpha-1a adrenergic receptor was evaluated by cloned receptor binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 5.10nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:In vitro binding affinity towards cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6.40nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 6.60nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1B adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 7.30nMAssay Description:In vitro binding affinity towards cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7.30nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 7.40nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 7.5nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 8.80nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 9.70nMAssay Description:In vitro binding affinity towards cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:In vitro binding affinity towards cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1B adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1B adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1D adrenergic receptor.More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 43nMAssay Description:Compound was evaluated for the displacement of labelled MK-499 from the cloned channel expressed in HEK cells (Ikrchannel)More data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:Binding affinity against human Alpha-1a adrenergic receptor was evaluated by cloned receptor binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Binding affinity against human Alpha-1d adrenergic receptor was evaluated by cloned receptor binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 61nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:In vitro binding affinity towards cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 75nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 77nMAssay Description:In vitro binding affinity towards cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 87nMAssay Description:Binding affinity against human Alpha-1a adrenergic receptor was evaluated by cloned receptor binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 98nMAssay Description:In vitro binding affinity towards cloned human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 98nMAssay Description:Binding affinity against human Alpha-1a adrenergic receptor was evaluated by cloned receptor binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Binding affinity against human Alpha-1a adrenergic receptor was evaluated by cloned receptor binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 128nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1D adrenergic receptor.More data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:In vitro binding affinity towards cloned human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair