Affinity DataKi: 1.60nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.80nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.80nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6.80nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 9.10nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 9.40nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 59nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 65nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 68nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 87nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 99nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+3nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+3nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+3nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.60E+3nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7.30E+3nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+4nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.178nMAssay Description:Inhibition of gamma secretase-mediated amyloid beta42 production in human H4 cells expressing human APP swedish mutantMore data for this Ligand-Target Pair
Affinity DataIC50: 0.210nMAssay Description:Inhibition of human recombinant ACC2 expressed in CHO cells after 1 hr by fluorescence readerMore data for this Ligand-Target Pair
Affinity DataIC50: 0.225nMAssay Description:Inhibition of gamma secretase-mediated amyloid beta42 production in human H4 cells expressing human APP swedish mutantMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human recombinant ACC2 expressed in CHO cells after 1 hr by fluorescence readerMore data for this Ligand-Target Pair
Affinity DataIC50: 0.310nMAssay Description:Inhibition of human recombinant ACC2 expressed in CHO cells after 1 hr by fluorescence readerMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.990nMAssay Description:Inhibition of gamma secretase-mediated amyloid beta42 production in human H4 cells expressing human APP swedish mutantMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of gamma secretase-mediated amyloid beta42 production in human H4 cells expressing human APP swedish mutantMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of gamma secretase-mediated amyloid beta42 production in human H4 cells expressing human APP swedish mutantMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human GPR40 expressed HEK293 cells assessed as effect on intracellular calcium concentration by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.75nMAssay Description:Inhibition of gamma secretase-mediated amyloid beta42 production in human H4 cells expressing human APP swedish mutantMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of gamma secretase-mediated amyloid beta42 production in human H4 cells expressing human APP swedish mutantMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human GPR40 expressed HEK293 cells assessed as effect on intracellular calcium concentration by FLIPR assayMore data for this Ligand-Target Pair