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Found 327 with Last Name = 'dodic' and Initial = 'n'
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050597(1-Ethyl-3-methyl-6-(5-nitro-2-propoxy-phenyl)-1,5-...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050584(1-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro-1H-pyrazolo[3...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050582(CHEMBL43443 | N-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050605(CHEMBL297864 | [3-(1,3-Dimethyl-4-oxo-4,5-dihydro-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050619(3-Methyl-6-(2-propoxy-phenyl)-1-propyl-1,5-dihydro...)
Affinity DataIC50:  1nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050627(CHEMBL298478 | Thiophene-2-carboxylic acid [3-(1,3...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050626(1-Ethyl-3-methyl-6-[5-(5-phenyl-1H-[1,2,4]triazol-...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050595(1-Ethyl-3-methyl-6-[5-(4-methyl-thiazol-2-yl)-2-pr...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050622(1-Ethyl-3-methyl-6-(2-propoxy-phenyl)-1,5-dihydro-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050620(CHEMBL46771 | N-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050579(CHEMBL42886 | [3-(1,3-Dimethyl-4-oxo-4,5-dihydro-1...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050580(CHEMBL416267 | N-[3-(1-Ethyl-3-methyl-4-oxo-4,5-di...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050577(1-Ethyl-3-methyl-6-[2-propoxy-5-(2-pyridin-3-yl-th...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050603(1-[3-(1,3-Dimethyl-4-oxo-4,5-dihydr o-1H-pyrazolo[...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050618(CHEMBL291178 | [3-(1,3-Dimethyl-4-oxo-4,5-dihydro-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050611(1,3-Dimethyl-6-[5-(2-methyl-thiazol-4-yl)-2-propox...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050593(1,3-Dimethyl-6-[5-(2-phenyl-thiazol-4-yl)-2-propox...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050590(1,3-Dimethyl-6-[5-(4-methyl-thiazol-2-yl)-2-propox...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Laboratoire Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50271572(1-[4-Chlorophenylcarbonyl]-4-[4-(pyridin-4-yl)phen...)
Affinity DataIC50:  3nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050614(1-Ethyl-3-methyl-6-[5-(2-phenyl-thiazol-4-yl)-2-pr...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050585(1-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro-1H-pyrazolo[3...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050596(1-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro-1H-pyrazolo[3...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050610(1-Ethyl-3-methyl-6-[5-(2-methyl-thiazol-4-yl)-2-pr...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050576(1,3-Dimethyl-6-(2-propoxy-5-thiazol-2-yl-phenyl)-1...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050598(CHEMBL45367 | N-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050592(CHEMBL46621 | N-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050600(CHEMBL298294 | N-[3-(1-Ethyl-3-methyl-4-oxo-4,5-di...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050599(1,3-Dimethyl-6-[5-(5-methyl-thiophen-2-yl)-2-propo...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050575(1,3-Dimethyl-6-(5-nitro-2-propoxy-phenyl)-1,5-dihy...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050621(1,3-Dimethyl-6-[5-(2-morpholin-4-yl-acetyl)-2-prop...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050624(6-(5-Dimethylamino-2-propoxy-phenyl)-1-ethyl-3-met...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050581(1,3-Dimethyl-6-(2-propoxy-5-thiophen-2-yl-phenyl)-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050602(6-[5-(5-Amino-1H-[1,2,4]triazol-3-ylamino)-2-propo...)
Affinity DataIC50:  5nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050615(6-(5-Dimethylamino-2-propoxy-phenyl)-1,3-dimethyl-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Laboratoire Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50271622(1-[4-Chlorophenylsulfonyl]-4-[4-(4-methylpiperazin...)
Affinity DataIC50:  6nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050616(1-Butyl-3-methyl-6-(2-propoxy-phenyl)-1,5-dihydro-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050617(6-(5-Amino-2-propoxy-phenyl)-1-ethyl-3-methyl-1,5-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050574(3-Methyl-6-(2-propoxy-phenyl)-1-(2,2,2-trifluoro-e...)
Affinity DataIC50:  7nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050607(1,3-Dimethyl-6-(2-propoxy-phenyl)-1,5-dihydro-pyra...)
Affinity DataIC50:  8nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50470139(CHEMBL46745)
Affinity DataIC50:  8.59nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050606(6-(5-Amino-2-propoxy-phenyl)-1,3-dimethyl-1,5-dihy...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50118668(CHEMBL3617086)
Affinity DataIC50:  10nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Laboratoire Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50271571(1-[4-Chlorophenylsulfonyl]-4-[4-(pyridin-4-yl)phen...)
Affinity DataIC50:  13nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50118669(CHEMBL3617083)
Affinity DataIC50:  13nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50118637(CHEMBL3617084)
Affinity DataIC50:  13nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxo Research And Development

Curated by ChEMBL
LigandPNGBDBM50470155(CHEMBL288971)
Affinity DataIC50:  14.8nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50118665(CHEMBL3617085)
Affinity DataIC50:  16nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293525(5-methyl-2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50118672(CHEMBL3617082)
Affinity DataIC50:  16nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50118524(CHEMBL3617080)
Affinity DataIC50:  20nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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