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Found 71 with Last Name = 'douglas' and Initial = 'c'
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50285488(1N-[23-[1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-20...)
Affinity DataIC50:  5nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50285491(10,12-Dimethyl-tetradecanoic acid [6-[1,2-dihydrox...)
Affinity DataIC50:  7nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50285479(10,12-Dimethyl-tetradecanoic acid [6-[1,2-dihydrox...)
Affinity DataIC50:  7nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50285475(1N-[23-[1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-20...)
Affinity DataIC50:  9nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50285481(10,12-Dimethyl-tetradecanoic acid {3-(3-amino-1-hy...)
Affinity DataIC50:  10nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50043898(10,12-Dimethyl-tetradecanoic acid [3-(3-amino-1-hy...)
Affinity DataIC50:  10nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8509((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-4-(...)
Affinity DataIC50:  37nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50285478(1N-{20-[2-(6-aminohexylcarbamoyl)-1-hydroxyethyl]-...)
Affinity DataIC50:  38nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8513((2R)-5-[(aminiumylmethanimidoyl)amino]-2-[(4-fluor...)
Affinity DataIC50:  40nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8501((2R)-2-cyclohexyl-2-[(4-fluoro-3-methylbenzene)sul...)
Affinity DataIC50:  42nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8512((2R)-3-(2-aminiumylethoxy)-2-[(4-fluoro-3-methylbe...)
Affinity DataIC50:  48nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8502((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  50nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8507((2R)-3-cyclopropyl-2-[(4-fluoro-3-methylbenzene)su...)
Affinity DataIC50:  51nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8503((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  54nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8511((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-4-(...)
Affinity DataIC50:  57nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8510((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-4-[...)
Affinity DataIC50:  59nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8500((2R)-2-cyclopentyl-2-[(4-fluoro-3-methylbenzene)su...)
Affinity DataIC50:  64nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8508((2R,3S)-3-cyclopropyl-2-[(4-fluoro-3-methylbenzene...)
Affinity DataIC50:  65nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8506((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  67nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8505((2R,3S)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-...)
Affinity DataIC50:  67nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50285493(10,12-Dimethyl-tetradecanoic acid {3-(2-carbamoyl-...)
Affinity DataIC50:  70nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8496((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  70nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50043897(10,12-Dimethyl-tetradecanoic acid [3-(2-carbamoyl-...)
Affinity DataIC50:  70nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8514(4-[(3R)-3-[(4-fluoro-3-methylbenzene)sulfonamido]-...)
Affinity DataIC50:  75nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50285476(10,12-Dimethyl-tetradecanoic acid {11,20,25-trihyd...)
Affinity DataIC50:  80nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8495((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  100nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50285489(10,12-Dimethyl-tetradecanoic acid [3-(2-cyano-1-hy...)
Affinity DataIC50:  100nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50285480(10,12-Dimethyl-tetradecanoic acid {3-(2-cyano-1-hy...)
Affinity DataIC50:  100nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50285490(10,12-Dimethyl-tetradecanoic acid {3-(2-hydrazinoc...)
Affinity DataIC50:  110nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8498((2R)-2-cyclopropyl-2-[(4-fluoro-3-methylbenzene)su...)
Affinity DataIC50:  120nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8504(2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-hydrox...)
Affinity DataIC50:  120nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50285485(10,12-Dimethyl-tetradecanoic acid [11,20,25-trihyd...)
Affinity DataIC50:  120nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8499((2R)-2-cyclobutyl-2-[(4-fluoro-3-methylbenzene)sul...)
Affinity DataIC50:  130nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8479((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  130nMpH: 7.0 T: 2°CAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8494((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  130nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50285487(3-{18-(10,12-Dimethyl-tetradecanoylamino)-11,20,25...)
Affinity DataIC50:  180nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50285484(10,12-Dimethyl-tetradecanoic acid {3-(1,3-dihydrox...)
Affinity DataIC50:  200nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50285492(1N-[20-[3-di(cyanomethyl)amino-1-hydroxypropyl]-23...)
Affinity DataIC50: >200nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50285486(1N-{20-[2-(5-carboxymethylcarbamoyl)-1-hydroxyethy...)
Affinity DataIC50:  250nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8476((2R)-2-[(4-fluorobenzene)sulfonamido]-N-hydroxy-3-...)
Affinity DataIC50:  290nMpH: 7.0 T: 2°CAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8497((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  300nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50285483(10,12-Dimethyl-tetradecanoic acid [3-(3-acetylamin...)
Affinity DataIC50:  300nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8478((2R)-N-hydroxy-3-methyl-2-[(3-methylbenzene)sulfon...)
Affinity DataIC50:  400nMpH: 7.0 T: 2°CAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50285482(3-{18-(10,12-Dimethyl-tetradecanoylamino)-11,20,25...)
Affinity DataIC50:  400nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8488((2R)-2-[(4-fluoronaphthalene-1-)sulfonamido]-N-hyd...)
Affinity DataIC50:  460nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8490((2R)-2-{[4-fluoro-3-(hydroxymethyl)benzene]sulfona...)
Affinity DataIC50:  600nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8493((2R)-N-hydroxy-3-methyl-2-{[5-(1,2,3-thiadiazol-5-...)
Affinity DataIC50:  810nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50285477(1N-{20-[2-(5-carboxycarbamoyl)-1-hydroxyethyl]-2,1...)
Affinity DataIC50:  900nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8466((2R)-N-hydroxy-2-[(4-methoxybenzene)sulfonamido]-3...)
Affinity DataIC50:  900nMpH: 7.0 T: 2°CAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8473((2R)-2-benzenesulfonamido-N-hydroxy-3-methylbutana...)
Affinity DataIC50:  1.10E+3nMpH: 7.0 T: 2°CAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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