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Found 131 with Last Name = 'dumais' and Initial = 'l'
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453060(CHEMBL4203893)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453029(CHEMBL4216115)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453053(CHEMBL4213802)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453052(CHEMBL4203378)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453053(CHEMBL4213802)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453034(CHEMBL4211859)
Affinity DataIC50:  9.80nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453028(CHEMBL4204225)
Affinity DataIC50:  16nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453045(CHEMBL4215570)
Affinity DataIC50:  21nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453065(CHEMBL4212402)
Affinity DataIC50:  23nMAssay Description:Inhibition of caspase-1 in human THP1 cells assessed as decrease in LPS-induced IL-1beta secretion after overnight incubation by sandwich immunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453029(CHEMBL4216115)
Affinity DataIC50:  27nMAssay Description:Inhibition of caspase-1 in human THP1 cells assessed as decrease in LPS-induced IL-1beta secretion after overnight incubation by sandwich immunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453053(CHEMBL4213802)
Affinity DataIC50:  32nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at 20 times Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453034(CHEMBL4211859)
Affinity DataIC50:  38nMAssay Description:Inhibition of caspase-1 in human THP1 cells assessed as decrease in LPS-induced IL-1beta secretion after overnight incubation by sandwich immunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453030(CHEMBL4208166)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453053(CHEMBL4213802)
Affinity DataIC50:  48nMAssay Description:Inhibition of caspase-1 in human THP1 cells assessed as decrease in LPS-induced IL-1beta secretion after overnight incubation by sandwich immunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453052(CHEMBL4203378)
Affinity DataIC50:  50nMAssay Description:Inhibition of caspase-1 in human THP1 cells assessed as decrease in LPS-induced IL-1beta secretion after overnight incubation by sandwich immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453060(CHEMBL4203893)
Affinity DataIC50:  53nMAssay Description:Inhibition of caspase-1 in human THP1 cells assessed as decrease in LPS-induced IL-1beta secretion after overnight incubation by sandwich immunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453031(CHEMBL4211143)
Affinity DataIC50:  66nMAssay Description:Inhibition of caspase-1 in human THP1 cells assessed as decrease in LPS-induced IL-1beta secretion after overnight incubation by sandwich immunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453064(CHEMBL4206773)
Affinity DataIC50:  76nMAssay Description:Inhibition of caspase-1 in human THP1 cells assessed as decrease in LPS-induced IL-1beta secretion after overnight incubation by sandwich immunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453028(CHEMBL4204225)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at 20 times Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453045(CHEMBL4215570)
Affinity DataIC50:  140nMAssay Description:Inhibition of caspase-1 in human THP1 cells assessed as decrease in LPS-induced IL-1beta secretion after overnight incubation by sandwich immunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453034(CHEMBL4211859)
Affinity DataIC50:  160nMAssay Description:Inhibition of caspase-1 in human monocyte-derived macrophages assessed as decrease in LPS-induced IL-1beta secretion after 24 hrs by sandwich immunoa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453061(CHEMBL4203155)
Affinity DataIC50:  200nMAssay Description:Inhibition of caspase-1 in human THP1 cells assessed as decrease in LPS-induced IL-1beta secretion after overnight incubation by sandwich immunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453062(CHEMBL4207501)
Affinity DataIC50:  210nMAssay Description:Inhibition of caspase-1 in human THP1 cells assessed as decrease in LPS-induced IL-1beta secretion after overnight incubation by sandwich immunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453063(CHEMBL4216830)
Affinity DataIC50:  360nMAssay Description:Inhibition of caspase-1 in human THP1 cells assessed as decrease in LPS-induced IL-1beta secretion after overnight incubation by sandwich immunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453040(CHEMBL4218951)
Affinity DataIC50:  501nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453027(CHEMBL4208767)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-5(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453034(CHEMBL4211859)
Affinity DataIC50:  2.98E+3nMAssay Description:Inhibition of human recombinant caspase-5 using AC-WEHD-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453054(CHEMBL4213265)
Affinity DataIC50:  5.01E+3nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453040(CHEMBL4218951)
Affinity DataIC50:  7.94E+3nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at 20 times Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453034(CHEMBL4211859)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant caspase-3 using Ac-DEVD-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453034(CHEMBL4211859)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant caspase-8 using Ac-IETD-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453034(CHEMBL4211859)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant caspase-7 using Ac-DEVD-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-6(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453034(CHEMBL4211859)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant caspase-6 using Ac-VEID-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453043(CHEMBL4202809)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453035(CHEMBL4215229)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at 20 times Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453044(CHEMBL4214469)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453035(CHEMBL4215229)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453054(CHEMBL4213265)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at 20 times Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453041(CHEMBL4209211)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453041(CHEMBL4209211)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at 20 times Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453042(CHEMBL4215468)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at 20 times Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453059(CHEMBL4213490)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at 20 times Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453027(CHEMBL4208767)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at 20 times Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453043(CHEMBL4202809)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at 20 times Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453044(CHEMBL4214469)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at 20 times Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453042(CHEMBL4215468)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453059(CHEMBL4213490)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of human recombinant caspase-1 using AC-WEHD-AMC as substrate at Km after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50457541(CHEMBL4216161)
Affinity DataEC50:  7.40nMAssay Description:Agonist activity at GAL4 DNA-binding domain-tagged RARgamma (unknown origin) ligand-binding domain expressed in human HG5LN cells incubated for 18 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50457542(CHEMBL4212472)
Affinity DataEC50:  11nMAssay Description:Agonist activity at GAL4 DNA-binding domain-tagged RARalpha (unknown origin) ligand-binding domain expressed in human HG5LN cells incubated for 18 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50457543(CHEMBL3934863)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GAL4 DNA-binding domain-tagged RARalpha (unknown origin) ligand-binding domain expressed in human HG5LN cells incubated for 18 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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