Compile Data Set for Download or QSAR
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Found 260 with Last Name = 'ebdrup' and Initial = 's'
TargetCholinesterase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138750(3-(4-Chloro-phenyl)-5-methylsulfanyl-[1,2,4]triazo...)
Affinity DataIC50: <10nMAssay Description:Inhibitory concentration against butyrylcholinesterase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138752(5-Methylsulfanyl-3-((E)-styryl)-[1,2,4]triazole-1-...)
Affinity DataIC50: <10nMAssay Description:Inhibitory concentration against acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138756(CHEMBL335158 | [3-(4-Chloro-phenyl)-5-hexylsulfany...)
Affinity DataIC50: <10nMAssay Description:Inhibitory concentration against acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138750(3-(4-Chloro-phenyl)-5-methylsulfanyl-[1,2,4]triazo...)
Affinity DataIC50:  20nMAssay Description:Inhibition of hormone sensitive lipase (HSL).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50224134(CHEMBL238293 | pyrrolidine-1-carboxylic acid 4-(5-...)
Affinity DataIC50:  23nMAssay Description:Inhibition of recombinant human hormone-sensitive lipaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50224161((4-methoxy-phenyl)-methyl-carbamic acid 4-(5-trifl...)
Affinity DataIC50:  23nMAssay Description:Inhibition of recombinant human hormone-sensitive lipaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138739(4-tert-Butyl-N-[4-(5-methoxy-2-oxo-[1,3,4]oxadiazo...)
Affinity DataIC50:  23nMAssay Description:Inhibition of hormone sensitive lipase (HSL).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138745((3-(4-chlorophenyl)-5-(methylthio)-1H-1,2,4-triazo...)
Affinity DataIC50:  26nMAssay Description:Inhibitory concentration against acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50224139((2-chloro-phenyl)-methyl-carbamic acid 4-(5-triflu...)
Affinity DataIC50:  26nMAssay Description:Inhibition of recombinant human hormone-sensitive lipaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138743(5-Methylsulfanyl-3-p-tolyl-[1,2,4]triazole-1-carbo...)
Affinity DataIC50:  30nMAssay Description:Inhibition of hormone sensitive lipase (HSL).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50224142(CHEMBL241552 | methyl-o-tolyl-carbamic acid 4-(tri...)
Affinity DataIC50:  39nMAssay Description:Inhibition of recombinant human hormone-sensitive lipaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50224154(CHEMBL235751 | methyl-phenyl-carbamic acid 4-(5-ch...)
Affinity DataIC50:  46nMAssay Description:Inhibition of recombinant human hormone-sensitive lipaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50224144(CHEMBL238085 | methyl-phenyl-carbamic acid 4-(5-tr...)
Affinity DataIC50:  46nMAssay Description:Inhibition of recombinant human hormone-sensitive lipaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138731(3-(4-Chloro-phenyl)-5-ethylsulfanyl-[1,2,4]triazol...)
Affinity DataIC50:  50nMAssay Description:Inhibitory concentration against butyrylcholinesterase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138748(5-Methylsulfanyl-3-naphthalen-2-yl-[1,2,4]triazole...)
Affinity DataIC50:  50nMAssay Description:Inhibitory concentration against acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50224158((2-Methoxy-phenyl)-methyl-carbamic acid 4-(5-trifl...)
Affinity DataIC50:  51nMAssay Description:Inhibition of recombinant human hormone-sensitive lipaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138731(3-(4-Chloro-phenyl)-5-ethylsulfanyl-[1,2,4]triazol...)
Affinity DataIC50:  56nMAssay Description:Inhibitory concentration against acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138742(3-(4-Chloro-phenyl)-5-propylsulfanyl-[1,2,4]triazo...)
Affinity DataIC50:  60nMAssay Description:Inhibition of hormone sensitive lipase (HSL).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138758(3-(4-Chloro-phenyl)-5-cyclopropylmethylsulfanyl-[1...)
Affinity DataIC50:  62nMAssay Description:Inhibition of hormone sensitive lipase (HSL).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50224155(CHEMBL241548 | piperidine-1-carboxylic acid 4-(5-t...)
Affinity DataIC50:  65nMAssay Description:Inhibition of recombinant human hormone-sensitive lipaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50224141((3-chloro-phenyl)-methyl-carbamic acid 4-(5-triflu...)
Affinity DataIC50:  71nMAssay Description:Inhibition of recombinant human hormone-sensitive lipaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development

Curated by ChEMBL
LigandPNGBDBM50190500(6-chloro-3-(1-methyl-1-phenylethyl)amino-4H-thieno...)
Affinity DataIC50:  81nMAssay Description:Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cells in presence of 2 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50109551((2S)-2-ETHOXY-3-{4-[2-(10H-PHENOXAZIN-10-YL)ETHOXY...)
Affinity DataIC50:  92nMAssay Description:Receptor binding affinity of the compound to human Peroxisome proliferator activated receptor gamma against [3H]-ragalitazar radioligandMore data for this Ligand-Target Pair
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138733(5-Methylsulfanyl-3-(4-trifluoromethyl-phenyl)-[1,2...)
Affinity DataIC50:  100nMAssay Description:Inhibition of hormone sensitive lipase (HSL).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138761(5-Methylsulfanyl-3-p-tolyl-[1,2,4]triazole-1-carbo...)
Affinity DataIC50:  100nMAssay Description:Inhibition of hormone sensitive lipase (HSL).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138733(5-Methylsulfanyl-3-(4-trifluoromethyl-phenyl)-[1,2...)
Affinity DataIC50:  100nMAssay Description:Inhibitory concentration against butyrylcholinesterase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138759(5-Methylsulfanyl-3-(4-trifluoromethoxy-phenyl)-[1,...)
Affinity DataIC50:  100nMAssay Description:Inhibition of hormone sensitive lipase (HSL).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138745((3-(4-chlorophenyl)-5-(methylthio)-1H-1,2,4-triazo...)
Affinity DataIC50:  100nMAssay Description:Inhibition of hormone sensitive lipase (HSL).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138747((3-(4-chlorophenyl)-5-(cyclopropylmethylthio)-1H-1...)
Affinity DataIC50:  100nMAssay Description:Inhibitory concentration against acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138750(3-(4-Chloro-phenyl)-5-methylsulfanyl-[1,2,4]triazo...)
Affinity DataIC50:  100nMAssay Description:Inhibitory concentration against acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138742(3-(4-Chloro-phenyl)-5-propylsulfanyl-[1,2,4]triazo...)
Affinity DataIC50:  100nMAssay Description:Inhibitory concentration against butyrylcholinesterase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50224169(4-hydroxymethyl-piperidine-1-carboxylic acid 4-(5-...)
Affinity DataIC50:  110nMAssay Description:Inhibition of recombinant human hormone-sensitive lipaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50224151(4-methyl-piperidine-1-carboxylic acid 4-(5-trifluo...)
Affinity DataIC50:  120nMAssay Description:Inhibition of recombinant human hormone-sensitive lipaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138748(5-Methylsulfanyl-3-naphthalen-2-yl-[1,2,4]triazole...)
Affinity DataIC50:  130nMAssay Description:Inhibitory concentration against butyrylcholinesterase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138749(3-(4-Chloro-phenyl)-5-methylsulfanyl-[1,2,4]triazo...)
Affinity DataIC50:  160nMAssay Description:Inhibition of hormone sensitive lipase (HSL).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138735((S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-c...)
Affinity DataIC50:  170nMAssay Description:Inhibition of hormone sensitive lipase (HSL).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138737(3-(4-Chloro-phenyl)-5-(2,2,2-trifluoro-ethylsulfan...)
Affinity DataIC50:  170nMAssay Description:Inhibition of hormone sensitive lipase (HSL).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138743(5-Methylsulfanyl-3-p-tolyl-[1,2,4]triazole-1-carbo...)
Affinity DataIC50:  200nMAssay Description:Inhibitory concentration against butyrylcholinesterase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138759(5-Methylsulfanyl-3-(4-trifluoromethoxy-phenyl)-[1,...)
Affinity DataIC50:  200nMAssay Description:Inhibitory concentration against butyrylcholinesterase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138738(5-(hexylthio)-N,N-dimethyl-3-p-tolyl-1H-1,2,4-tria...)
Affinity DataIC50:  200nMAssay Description:Inhibitory concentration against acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138747((3-(4-chlorophenyl)-5-(cyclopropylmethylthio)-1H-1...)
Affinity DataIC50:  200nMAssay Description:Inhibition of hormone sensitive lipase (HSL).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138732(3-p-Tolyl-5-(2,2,2-trifluoro-ethylsulfanyl)-[1,2,4...)
Affinity DataIC50:  200nMAssay Description:Inhibitory concentration against acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138739(4-tert-Butyl-N-[4-(5-methoxy-2-oxo-[1,3,4]oxadiazo...)
Affinity DataIC50:  200nMAssay Description:Compound was tested to inhibit lipoprotein lipase (LPL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138731(3-(4-Chloro-phenyl)-5-ethylsulfanyl-[1,2,4]triazol...)
Affinity DataIC50:  210nMAssay Description:Inhibition of hormone sensitive lipase (HSL).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50224157(4-benzyl-piperidine 1-carboxylic acid 4-(5-trifluo...)
Affinity DataIC50:  210nMAssay Description:Inhibition of recombinant human hormone-sensitive lipaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138740(3-Biphenyl-4-yl-5-methylsulfanyl-[1,2,4]triazole-1...)
Affinity DataIC50:  230nMAssay Description:Inhibitory concentration against butyrylcholinesterase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50224167(CHEMBL241553 | methyl-m-tolyl-carbamic acid 4-(5-t...)
Affinity DataIC50:  250nMAssay Description:Inhibition of recombinant human hormone-sensitive lipaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138751(5-Methylsulfanyl-3-(4-trifluoromethoxy-phenyl)-[1,...)
Affinity DataIC50:  250nMAssay Description:Inhibition of hormone sensitive lipase (HSL).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50224165(CHEMBL237189 | morpholine-4-carboxylic acid 4-(5-t...)
Affinity DataIC50:  250nMAssay Description:Inhibition of recombinant human hormone-sensitive lipaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development

Curated by ChEMBL
LigandPNGBDBM50118359((2-Chloro-7,7-dioxo-4,7-dihydro-1,7-dithia-4,6-dia...)
Affinity DataIC50:  286nMAssay Description:Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cells in presence of 2 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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