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Found 158 with Last Name = 'ebright' and Initial = 'rh'
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM50391000(CB-01-11 | RIFAMYCIN)
Affinity DataIC50:  20nMT: 2°CAssay Description:Fluorescence-detected RNAP inhibition assays in Tables 1 and 4 were performed using a DNA fragment containing the lacUV5 promoter as a template and t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM50391000(CB-01-11 | RIFAMYCIN)
Affinity DataIC50:  30nMT: 2°CAssay Description:Fluorescence-detected RNAP inhibition assays in Tables 1 and 4 were performed using a DNA fragment containing the lacUV5 promoter as a template and t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase subunit alpha(Escherichia coli K-12)
TBA

US Patent
LigandPNGBDBM466524(US10800725, Compound 12)
Affinity DataIC50:  120nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM592137(US11572337, Compound 0MTK149)
Affinity DataIC50:  140nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM466519(US10800725, Compound 7)
Affinity DataIC50:  170nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit alpha(Escherichia coli K-12)
TBA

US Patent
LigandPNGBDBM466519(US10800725, Compound 7)
Affinity DataIC50:  210nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM592141(US11572337, Compound 0MTK158)
Affinity DataIC50:  220nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM466524(US10800725, Compound 12)
Affinity DataIC50:  220nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit alpha(Escherichia coli K-12)
TBA

US Patent
LigandPNGBDBM466521(US10800725, Compound 9)
Affinity DataIC50:  220nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM466521(US10800725, Compound 9)
Affinity DataIC50:  290nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM592173(US11572337, Compound 0MTK267)
Affinity DataIC50:  300nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM592161(US11572337, Compound 0MTK237)
Affinity DataIC50:  310nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM592133(US11572337, Compound 0MTK127)
Affinity DataIC50:  370nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM592145(US11572337, Compound 0MTK176)
Affinity DataIC50:  390nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM592132(US11572337, Compound 0MTK107)
Affinity DataIC50:  400nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM592142(US11572337, Compound 0MTK174)
Affinity DataIC50:  410nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit alpha(Escherichia coli K-12)
TBA

US Patent
LigandPNGBDBM466520(US10800725, Compound 8)
Affinity DataIC50:  420nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM592138(US11572337, Compound 0MTK154)
Affinity DataIC50:  420nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM592144(US11572337, Compound 0MTK175)
Affinity DataIC50:  450nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM466524(US10800725, Compound 12)
Affinity DataIC50:  460nMAssay Description:Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit alpha(Escherichia coli K-12)
TBA

US Patent
LigandPNGBDBM466522(US10800725, Compound 10)
Affinity DataIC50:  530nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM466520(US10800725, Compound 8)
Affinity DataIC50:  600nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM592146(US11572337, Compound 0MTK178)
Affinity DataIC50:  610nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit alpha(Escherichia coli K-12)
TBA

US Patent
LigandPNGBDBM466515(US10800725, Compound 3)
Affinity DataIC50:  630nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM466522(US10800725, Compound 10)
Affinity DataIC50:  640nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM592164(US11572337, Compound 0MTK256)
Affinity DataIC50:  650nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM466526(US10800725, Compound 14)
Affinity DataIC50:  680nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM592135(US11572337, Compound 0MTK146)
Affinity DataIC50:  690nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM592175(US11572337, Compound 0MTK269)
Affinity DataIC50:  700nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM592159(US11572337, Compound 0MTK232)
Affinity DataIC50:  720nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM592162(US11572337, Compound 0MTK238)
Affinity DataIC50:  770nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM466515(US10800725, Compound 3)
Affinity DataIC50:  770nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM592166(US11572337, Compound 0MTK260)
Affinity DataIC50:  780nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM466523(US10800725, Compound 11)
Affinity DataIC50:  780nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM592139(US11572337, Compound 0MTK155)
Affinity DataIC50:  790nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM592174(US11572337, Compound 0MTK268)
Affinity DataIC50:  800nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM592136(US11572337, Compound 0MTK148)
Affinity DataIC50:  800nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM592165(US11572337, Compound 0MTK257)
Affinity DataIC50:  800nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM592140(US11572337, Compound 0MTK156)
Affinity DataIC50:  820nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM592170(US11572337, Compound 0MTK264)
Affinity DataIC50:  820nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM592147(US11572337, Compound 0MTK180)
Affinity DataIC50:  830nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM466521(US10800725, Compound 9)
Affinity DataIC50:  840nMAssay Description:Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit alpha(Escherichia coli K-12)
TBA

US Patent
LigandPNGBDBM466523(US10800725, Compound 11)
Affinity DataIC50:  890nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM592134(US11572337, Compound 0MTK128)
Affinity DataIC50:  970nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit alpha(Escherichia coli K-12)
TBA

US Patent
LigandPNGBDBM466517(US10800725, Compound 5)
Affinity DataIC50:  1.10E+3nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit alpha(Escherichia coli K-12)
TBA

US Patent
LigandPNGBDBM466526(US10800725, Compound 14)
Affinity DataIC50:  1.10E+3nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM466519(US10800725, Compound 7)
Affinity DataIC50:  1.10E+3nMAssay Description:Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM466517(US10800725, Compound 5)
Affinity DataIC50:  1.10E+3nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Merck

LigandPNGBDBM592172(US11572337, Compound 0MTK266)
Affinity DataIC50:  1.20E+3nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM466518(US10800725, Compound 6)
Affinity DataIC50:  1.20E+3nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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