Affinity DataKi: 0.440nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 0.450nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured at second inhibition step by fluorome...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 0.490nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain expressed in Pichia pastoris using Cbz-Phe-Arg-AMC as substrate after 15 to 30 mins by fluores...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured at second inhibition step by fluorome...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured using Dixon equation by fluorometric ...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 4.20nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain expressed in Pichia pastoris using Cbz-Phe-Arg-AMC as substrate after 15 to 30 mins by fluores...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured using Dixon equation by fluorometric ...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 6.5nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain expressed in Pichia pastoris using Cbz-Phe-Arg-AMC as substrate after 15 to 30 mins by fluores...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured using Dixon equation by fluorometric ...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured using Dixon equation by fluorometric ...More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured using Dixon equation by fluorometric ...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured using Dixon equation by fluorometric ...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain expressed in Pichia pastoris using Cbz-Phe-Arg-AMC as substrate after 15 to 30 mins by fluores...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured at second inhibition step by fluorome...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured using Dixon equation by fluorometric ...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured at second inhibition step by fluorome...More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain expressed in Pichia pastoris using Cbz-Phe-Arg-AMC as substrate after 15 to 30 mins by fluores...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain expressed in Pichia pastoris using Cbz-Phe-Arg-AMC as substrate after 15 to 30 mins by fluores...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain expressed in Pichia pastoris using Cbz-Phe-Arg-AMC as substrate after 15 to 30 mins by fluores...More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured using Dixon equation by fluorometric ...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured at second inhibition step by fluorome...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured at second inhibition step by fluorome...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Competitive inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate by fluorometric enzyme assaysMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain expressed in Pichia pastoris using Cbz-Phe-Arg-AMC as substrate after 15 to 30 mins by fluores...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured at second inhibition step by fluorome...More data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain expressed in Pichia pastoris using Cbz-Phe-Arg-AMC as substrate after 15 to 30 mins by fluores...More data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of human CatL assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured using Dixon equation by fluorometric enzyme assaysMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 34nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured at second inhibition step by fluorome...More data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 35nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured at second inhibition step by fluorome...More data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Inhibition of human CatL assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured using Dixon equation by fluorometric enzyme assaysMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 45nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured at second inhibition step by fluorome...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 46nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured at second inhibition step by fluorome...More data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 47nMAssay Description:Competitive inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate by fluorometric enzyme assaysMore data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Inhibition of human liver CatL assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured at second inhibition step by fluorometric enzyme ...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain expressed in Pichia pastoris using Cbz-Phe-Arg-AMC as substrate after 15 to 30 mins by fluores...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 53nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured at second inhibition step by fluorome...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataKi: 56nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured at second inhibition step by fluorome...More data for this Ligand-Target Pair