Compile Data Set for Download or QSAR
maximum 50k data
Found 69 with Last Name = 'englund' and Initial = 'ee'
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426366(CHEMBL2326408)
Affinity DataIC50:  51nMAssay Description:Displacement of fluorescein-labeled 25-hydroxycholesterol from human RORgammat LBD (262-518) Escherichia coli BL21(DE3) after 6 hrs by fluorescence p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426366(CHEMBL2326408)
Affinity DataIC50:  51nMAssay Description:Displacement of fluorescein-labeled 25-hydroxycholesterol from human RORgammat LBD (262-518) Escherichia coli BL21(DE3) after 6 hrs by fluorescence p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354121(CHEMBL1836238)
Affinity DataIC50:  90nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354120(CHEMBL1836239)
Affinity DataIC50:  160nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354128(CHEMBL1836179)
Affinity DataIC50:  200nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426366(CHEMBL2326408)
Affinity DataIC50:  300nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in HEK293t cells co-expressing Gal4-DNA binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354125(CHEMBL1345685)
Affinity DataIC50:  430nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354119(CHEMBL1836233)
Affinity DataIC50:  470nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426377(CHEMBL2326703)
Affinity DataIC50:  800nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426372(CHEMBL2326412)
Affinity DataIC50:  800nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426370(CHEMBL2326414)
Affinity DataIC50:  800nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354126(CHEMBL1836236)
Affinity DataIC50:  810nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426371(CHEMBL2326413)
Affinity DataIC50:  1.00E+3nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426367(CHEMBL2326416)
Affinity DataIC50:  1.00E+3nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426366(CHEMBL2326408)
Affinity DataIC50:  1.10E+3nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354122(CHEMBL1836230)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426369(CHEMBL2326415)
Affinity DataIC50:  1.70E+3nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354117(CHEMBL1836234)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM46355(DIGOXIN | MLS000069819 | SMR000059217 | US10668094...)
Affinity DataIC50:  2.00E+3nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426368(CHEMBL1370683)
Affinity DataIC50:  2.50E+3nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426387(CHEMBL1337164)
Affinity DataIC50:  3.30E+3nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354127(CHEMBL1836177)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426376(CHEMBL2326409)
Affinity DataIC50:  3.30E+3nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354133(CHEMBL1836184)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426373(CHEMBL2321922)
Affinity DataIC50:  4.00E+3nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354130(CHEMBL1836181)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354129(CHEMBL1836180)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426366(CHEMBL2326408)
Affinity DataIC50:  4.50E+3nMAssay Description:Antagonist activity at TRalpha (unknown origin) expressed in HEK293t cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426378(CHEMBL2326702)
Affinity DataIC50:  4.70E+3nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354132(CHEMBL1836183)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426374(CHEMBL2326411)
Affinity DataIC50:  6.60E+3nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354116(CHEMBL1836235)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426366(CHEMBL2326408)
Affinity DataIC50:  1.00E+4nMAssay Description:Antagonist activity at LXRalpha (unknown origin) expressed in HEK293t cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426379(CHEMBL2326701)
Affinity DataIC50:  1.28E+4nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426366(CHEMBL2326408)
Affinity DataIC50:  1.30E+4nMAssay Description:Antagonist activity at TRbeta (unknown origin) expressed in HEK293t cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR1(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426366(CHEMBL2326408)
Affinity DataIC50:  1.40E+4nMAssay Description:Antagonist activity at ERRalpha (unknown origin) expressed in HEK293t cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426385(CHEMBL1518643)
Affinity DataIC50:  1.57E+4nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426384(CHEMBL2326697)
Affinity DataIC50:  2.25E+4nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354131(CHEMBL1836182)
Affinity DataIC50:  2.29E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426380(CHEMBL2326700)
Affinity DataIC50:  2.44E+4nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354124(CHEMBL1836237)
Affinity DataIC50:  2.75E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354118(CHEMBL1836240)
Affinity DataIC50:  2.76E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50354123(CHEMBL1833996)
Affinity DataIC50:  2.76E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426382(CHEMBL2326698)
Affinity DataIC50:  2.90E+4nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426375(CHEMBL2326410)
Affinity DataIC50:  3.00E+4nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426381(CHEMBL2326699)
Affinity DataIC50: >5.00E+4nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426383(CHEMBL1445011)
Affinity DataIC50: >5.00E+4nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
New York University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50426386(CHEMBL1879167)
Affinity DataIC50: >5.00E+4nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C11(Rattus norvegicus)
Nih Chemical Genomics Center

Curated by ChEMBL
LigandPNGBDBM50496715(CHEMBL1705547)
Affinity DataEC50:  330nMAssay Description:Agonist activity at TSHR (unknown origin) transiently transfected HEK-EM293 cells assessed as cAMP level after 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C11(Rattus norvegicus)
Nih Chemical Genomics Center

Curated by ChEMBL
LigandPNGBDBM50496716(CHEMBL1706950)
Affinity DataEC50:  4.34E+3nMAssay Description:Agonist activity at TSHR (unknown origin) transiently transfected HEK-EM293 cells assessed as cAMP level after 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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