Affinity DataKi: 7nM ΔG°: -46.2kJ/molepH: 6.0 T: 2°CAssay Description:TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob...More data for this Ligand-Target Pair
Affinity DataKi: 47nM ΔG°: -41.5kJ/molepH: 6.0 T: 2°CAssay Description:TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob...More data for this Ligand-Target Pair
Affinity DataKi: 190nMAssay Description:Competitive inhibition of recombinant trypanothione reductase from Trypanosoma brucei brucei S427 by Lineweaver burk methodMore data for this Ligand-Target Pair
Affinity DataKi: 270nMAssay Description:Competitive inhibition of recombinant trypanothione reductase from Trypanosoma brucei brucei S427 by Lineweaver burk methodMore data for this Ligand-Target Pair
Affinity DataKi: 320nMAssay Description:Competitive inhibition of recombinant trypanothione reductase from Trypanosoma brucei brucei S427 by Lineweaver burk methodMore data for this Ligand-Target Pair
Affinity DataKi: 400nM ΔG°: -36.3kJ/molepH: 6.0 T: 2°CAssay Description:TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob...More data for this Ligand-Target Pair
Affinity DataKi: 440nMAssay Description:Competitive inhibition of recombinant trypanothione reductase from Trypanosoma brucei brucei S427 by Lineweaver burk methodMore data for this Ligand-Target Pair
Affinity DataKi: 510nM ΔG°: -35.7kJ/molepH: 6.0 T: 2°CAssay Description:TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob...More data for this Ligand-Target Pair
Affinity DataKi: 1.46E+3nMAssay Description:Mixed type inhibition of recombinant trypanothione reductase from Trypanosoma brucei brucei S427 by Lineweaver burk methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.78E+3nMAssay Description:Mixed type inhibition of recombinant trypanothione reductase from Trypanosoma brucei brucei S427 by Lineweaver burk methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.27E+3nMAssay Description:Mixed type inhibition of recombinant trypanothione reductase from Trypanosoma brucei brucei S427 by Lineweaver burk methodMore data for this Ligand-Target Pair
TargetGlutathionylspermidine synthase(Crithidia fasciculata)
University Of Antwerp (Uia)
Curated by ChEMBL
University Of Antwerp (Uia)
Curated by ChEMBL
Affinity DataKi: 2.50E+3nMAssay Description:Inhibitory constant against amidase free Glutathionylspermidine Synthetase mutant (C79A)More data for this Ligand-Target Pair
TargetGlutathionylspermidine synthase(Crithidia fasciculata)
University Of Antwerp (Uia)
Curated by ChEMBL
University Of Antwerp (Uia)
Curated by ChEMBL
Affinity DataKi: 6.40E+3nMAssay Description:Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculataMore data for this Ligand-Target Pair
TargetGlutathionylspermidine synthase(Crithidia fasciculata)
University Of Antwerp (Uia)
Curated by ChEMBL
University Of Antwerp (Uia)
Curated by ChEMBL
Affinity DataKi: 6.40E+3nMAssay Description:Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculataMore data for this Ligand-Target Pair
TargetGlutathionylspermidine synthase(Crithidia fasciculata)
University Of Antwerp (Uia)
Curated by ChEMBL
University Of Antwerp (Uia)
Curated by ChEMBL
Affinity DataKi: 7.20E+3nMAssay Description:Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculataMore data for this Ligand-Target Pair
TargetGlutathionylspermidine synthase(Crithidia fasciculata)
University Of Antwerp (Uia)
Curated by ChEMBL
University Of Antwerp (Uia)
Curated by ChEMBL
Affinity DataKi: 7.20E+3nMAssay Description:In vitro binding affinity for Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 9.80E+3nM ΔG°: -28.4kJ/molepH: 6.0 T: 2°CAssay Description:TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob...More data for this Ligand-Target Pair
TargetGlutathionylspermidine synthase(Crithidia fasciculata)
University Of Antwerp (Uia)
Curated by ChEMBL
University Of Antwerp (Uia)
Curated by ChEMBL
Affinity DataKi: 1.00E+4nMAssay Description:Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculataMore data for this Ligand-Target Pair
TargetGlutathionylspermidine synthase(Crithidia fasciculata)
University Of Antwerp (Uia)
Curated by ChEMBL
University Of Antwerp (Uia)
Curated by ChEMBL
Affinity DataKi: 1.00E+4nMAssay Description:Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculataMore data for this Ligand-Target Pair
TargetGlutathionylspermidine synthase(Crithidia fasciculata)
University Of Antwerp (Uia)
Curated by ChEMBL
University Of Antwerp (Uia)
Curated by ChEMBL
Affinity DataKi: 1.04E+4nMAssay Description:Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculataMore data for this Ligand-Target Pair
TargetGlutathionylspermidine synthase(Crithidia fasciculata)
University Of Antwerp (Uia)
Curated by ChEMBL
University Of Antwerp (Uia)
Curated by ChEMBL
Affinity DataKi: 1.04E+4nMAssay Description:Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculataMore data for this Ligand-Target Pair
Affinity DataKi: 1.06E+4nM ΔG°: -28.2kJ/molepH: 6.0 T: 2°CAssay Description:TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob...More data for this Ligand-Target Pair
Affinity DataKi: 1.08E+4nMAssay Description:Inhibitory activity against recombinant Trypanosoma cruzi (T. cruzi) Trypanothione reductase (linear competitive type)More data for this Ligand-Target Pair
TargetGlutathionylspermidine synthase(Crithidia fasciculata)
University Of Antwerp (Uia)
Curated by ChEMBL
University Of Antwerp (Uia)
Curated by ChEMBL
Affinity DataKi: 1.40E+4nMAssay Description:Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculataMore data for this Ligand-Target Pair
TargetGlutathionylspermidine synthase(Crithidia fasciculata)
University Of Antwerp (Uia)
Curated by ChEMBL
University Of Antwerp (Uia)
Curated by ChEMBL
Affinity DataKi: 1.40E+4nMAssay Description:Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculataMore data for this Ligand-Target Pair
Affinity DataKi: 1.87E+4nMAssay Description:Inhibitory activity against recombinant Trypanosoma cruzi (T. cruzi) Trypanothione reductase (linear competitive type)More data for this Ligand-Target Pair
Affinity DataKi: 2.11E+4nM ΔG°: -26.5kJ/molepH: 6.0 T: 2°CAssay Description:TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob...More data for this Ligand-Target Pair
Affinity DataKi: 2.12E+4nMAssay Description:Inhibitory activity against recombinant Trypanosoma cruzi (T. cruzi) Trypanothione reductase (linear competitive type)More data for this Ligand-Target Pair
Affinity DataKi: 2.30E+4nMAssay Description:Inhibitory activity against recombinant Trypanosoma cruzi (T. cruzi) Trypanothione reductase (linear competitive type)More data for this Ligand-Target Pair
Affinity DataKi: 2.39E+4nM ΔG°: -26.2kJ/molepH: 6.0 T: 2°CAssay Description:TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob...More data for this Ligand-Target Pair
TargetGlutathionylspermidine synthase(Crithidia fasciculata)
University Of Antwerp (Uia)
Curated by ChEMBL
University Of Antwerp (Uia)
Curated by ChEMBL
Affinity DataKi: 2.70E+4nMAssay Description:Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculataMore data for this Ligand-Target Pair
TargetGlutathionylspermidine synthase(Crithidia fasciculata)
University Of Antwerp (Uia)
Curated by ChEMBL
University Of Antwerp (Uia)
Curated by ChEMBL
Affinity DataKi: 2.70E+4nMAssay Description:Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculataMore data for this Ligand-Target Pair
Affinity DataKi: 3.02E+4nMAssay Description:Inhibitory activity against recombinant Trypanosoma cruzi (T. cruzi) Trypanothione reductase (linear competitive type)More data for this Ligand-Target Pair
TargetGlutathionylspermidine synthase(Crithidia fasciculata)
University Of Antwerp (Uia)
Curated by ChEMBL
University Of Antwerp (Uia)
Curated by ChEMBL
Affinity DataKi: 3.20E+4nMAssay Description:Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculataMore data for this Ligand-Target Pair
TargetGlutathionylspermidine synthase(Crithidia fasciculata)
University Of Antwerp (Uia)
Curated by ChEMBL
University Of Antwerp (Uia)
Curated by ChEMBL
Affinity DataKi: 3.20E+4nMAssay Description:Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculataMore data for this Ligand-Target Pair
TargetGlutathionylspermidine synthase(Crithidia fasciculata)
University Of Antwerp (Uia)
Curated by ChEMBL
University Of Antwerp (Uia)
Curated by ChEMBL
Affinity DataKi: 3.30E+4nMAssay Description:Tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculataMore data for this Ligand-Target Pair
TargetGlutathionylspermidine synthase(Crithidia fasciculata)
University Of Antwerp (Uia)
Curated by ChEMBL
University Of Antwerp (Uia)
Curated by ChEMBL
Affinity DataKi: 3.30E+4nMAssay Description:Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculataMore data for this Ligand-Target Pair
Affinity DataKi: 5.91E+4nMAssay Description:Inhibitory activity against recombinant Trypanosoma cruzi (T. cruzi) Trypanothione reductase (linear competitive type)More data for this Ligand-Target Pair
TargetGlutathionylspermidine synthase(Crithidia fasciculata)
University Of Antwerp (Uia)
Curated by ChEMBL
University Of Antwerp (Uia)
Curated by ChEMBL
Affinity DataKi: 6.00E+4nMAssay Description:Inhibition constant of the compound was evaluated against enzyme Glutathionylspermidine Synthetase wild-type enzymeMore data for this Ligand-Target Pair
TargetGlutathionylspermidine synthase(Crithidia fasciculata)
University Of Antwerp (Uia)
Curated by ChEMBL
University Of Antwerp (Uia)
Curated by ChEMBL
Affinity DataKi: 6.00E+4nMAssay Description:Compound was tested for linear non-competitive inhibitory activity against glutathionylspermidine synthetase.More data for this Ligand-Target Pair
TargetGlutathionylspermidine synthase(Crithidia fasciculata)
University Of Antwerp (Uia)
Curated by ChEMBL
University Of Antwerp (Uia)
Curated by ChEMBL
Affinity DataKi: 8.10E+4nMAssay Description:Concentration of the compound required for the inhibition of enzyme Glutathionylspermidine Synthetase wild-type enzymeMore data for this Ligand-Target Pair
TargetGlutathionylspermidine synthase(Crithidia fasciculata)
University Of Antwerp (Uia)
Curated by ChEMBL
University Of Antwerp (Uia)
Curated by ChEMBL
Affinity DataKi: 8.10E+4nMAssay Description:Inhibition constant of the compound was evaluated against enzyme Glutathionylspermidine Synthetase wild-type enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 1.27E+5nMAssay Description:Inhibitory activity against recombinant Trypanosoma cruzi (T. cruzi) Trypanothione reductase (linear competitive type)More data for this Ligand-Target Pair
Affinity DataKi: 1.41E+5nM ΔG°: -21.8kJ/molepH: 6.0 T: 2°CAssay Description:TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob...More data for this Ligand-Target Pair
Affinity DataKi: >2.00E+5nM ΔG°: >-21.0kJ/molepH: 6.0 T: 2°CAssay Description:TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob...More data for this Ligand-Target Pair
Affinity DataKi: 2.16E+5nMAssay Description:Inhibitory activity against recombinant Trypanosoma cruzi (T. cruzi) Trypanothione reductase (linear competitive type)More data for this Ligand-Target Pair
Affinity DataKi: 2.88E+5nM ΔG°: -20.1kJ/molepH: 6.0 T: 2°CAssay Description:TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob...More data for this Ligand-Target Pair
TargetGlutathionylspermidine synthase(Crithidia fasciculata)
University Of Antwerp (Uia)
Curated by ChEMBL
University Of Antwerp (Uia)
Curated by ChEMBL
Affinity DataKi: 2.90E+5nMAssay Description:Compound was tested for linear non-competitive inhibitory activity against glutathionylspermidine synthetase.More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins prior to substrate addition by ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins prior to substrate addition by ...More data for this Ligand-Target Pair