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Found 160 with Last Name = 'feixas' and Initial = 'j'
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50123473(1-[9-(3-Chloro-4-methoxy-benzylamino)-3-ethyl-3H-2...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human Phosphodiesterase 5; IC50 range 0.03-0.3 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165805(4-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydro-3,...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165811(7-Benzyl-4-sec-butyl-9-methyl-2-phenyl-7H-3,3a,5,7...)
Affinity DataIC50:  34nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165812(7-Benzyl-4-sec-butyl-9-methyl-2-pyridin-2-yl-7H-3,...)
Affinity DataIC50:  39nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bos taurus)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  40nMAssay Description:Inhibition of bovine Phosphodiesterase 6 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165826(CHEMBL193746 | Phosphoric acid mono-[3-(4-sec-buty...)
Affinity DataIC50:  59nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bos taurus)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165810(5-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydro-3,...)
Affinity DataIC50:  63nMAssay Description:Inhibition of bovine Phosphodiesterase 6 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165822(7-Benzyl-4-(1-ethyl-propyl)-9-methyl-2-phenyl-7H-3...)
Affinity DataIC50:  67nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165818(7-Benzyl-9-methyl-2-phenyl-4-m-tolyl-7H-3,3a,5,7,8...)
Affinity DataIC50:  75nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165814(7-Benzyl-9-methyl-2-phenyl-4-pyridin-2-yl-7H-3,3a,...)
Affinity DataIC50:  81nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165806(7-Benzyl-9-methyl-2,4-diphenyl-7H-3,3a,5,7,8-penta...)
Affinity DataIC50:  81nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165810(5-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydro-3,...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165827(7-Benzyl-4-methoxymethyl-9-methyl-2-phenyl-7H-3,3a...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165828(7-Benzyl-9-methyl-4-methylsulfanylmethyl-2-phenyl-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bos taurus)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165805(4-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydro-3,...)
Affinity DataIC50:  110nMAssay Description:Inhibition of bovine Phosphodiesterase 6 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165819(7-Benzyl-4,9-dimethyl-2-phenyl-7H-3,3a,5,7,8-penta...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165808(7-Benzyl-9-methyl-2-phenyl-4-pyridin-3-yl-7H-3,3a,...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  190nMAssay Description:In vitro inhibitory concentration against rat prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50084355(4-[3-(4-Methoxy-phenyl)-2-oxo-2,3-dihydro-oxazol-4...)
Affinity DataIC50:  210nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50105290(2-[7-Methoxy-4-(4-methyl-benzyl)-naphthalen-1-yl]-...)
Affinity DataIC50:  220nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  220nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  220nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165825(CHEMBL363638 | Phosphoric acid mono-[3-(4,9-dimeth...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50084352(4-[3-(3,4-Dichloro-phenyl)-5-methyl-2-oxo-2,3-dihy...)
Affinity DataIC50:  230nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  250nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165815(7-Benzyl-4,9-dimethyl-2-pyridin-2-yl-7H-3,3a,5,7,8...)
Affinity DataIC50:  270nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50084366(3-(4-Chloro-phenyl)-4-(4-methanesulfonyl-phenyl)-3...)
Affinity DataIC50:  320nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165809((E)-3-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydr...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50105302(2-[7-Methoxy-4-(4-methoxy-benzyl)-naphthalen-1-yl]...)
Affinity DataIC50:  330nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165823(7-Benzyl-4-ethoxymethyl-9-methyl-2-phenyl-7H-3,3a,...)
Affinity DataIC50:  350nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50105293(2-(4-Benzyl-7-methoxy-naphthalen-1-yl)-propionic a...)
Affinity DataIC50:  390nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50084359(4-[3-(3,4-Dichloro-phenyl)-2-oxo-2,3-dihydro-oxazo...)
Affinity DataIC50:  400nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165816(3-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydro-3,...)
Affinity DataIC50:  430nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165817(7-Benzyl-9-methyl-2-phenyl-4-pyridin-4-ylmethyl-7H...)
Affinity DataIC50:  450nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50084345(4-(4-Methanesulfonyl-phenyl)-3-p-tolyl-3H-oxazol-2...)
Affinity DataIC50:  480nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50084347(3-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-3...)
Affinity DataIC50:  510nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50084368(4-[3-(4-Fluoro-phenyl)-5-methyl-2-oxo-2,3-dihydro-...)
Affinity DataIC50:  510nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50084353(4-(2-Oxo-3-m-tolyl-2,3-dihydro-oxazol-4-yl)-benzen...)
Affinity DataIC50:  510nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50105303(2-[4-(4-Chloro-benzyl)-7-methoxy-naphthalen-1-yl]-...)
Affinity DataIC50:  520nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bos taurus)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165809((E)-3-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydr...)
Affinity DataIC50:  580nMAssay Description:Inhibition of bovine Phosphodiesterase 6 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bos taurus)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165816(3-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydro-3,...)
Affinity DataIC50:  590nMAssay Description:Inhibition of bovine Phosphodiesterase 6 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50084349(3-(2-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-3...)
Affinity DataIC50:  660nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50084346(3-(4-Ethyl-phenyl)-4-(4-methanesulfonyl-phenyl)-3H...)
Affinity DataIC50:  690nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50105289(2-[4-(4-Fluoro-benzyl)-7-methoxy-naphthalen-1-yl]-...)
Affinity DataIC50:  740nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM22369(4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)
Affinity DataIC50:  760nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50084370(4-[3-(3-Chloro-4-methoxy-phenyl)-2-oxo-2,3-dihydro...)
Affinity DataIC50:  780nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50084364(4-(2-Oxo-3-p-tolyl-2,3-dihydro-oxazol-4-yl)-benzen...)
Affinity DataIC50:  790nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50105288(CHEMBL91139 | [4-(4-Chloro-benzyl)-7-methoxy-napht...)
Affinity DataIC50:  880nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50084355(4-[3-(4-Methoxy-phenyl)-2-oxo-2,3-dihydro-oxazol-4...)
Affinity DataIC50:  900nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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