Affinity DataIC50: 1.40nMAssay Description:Inhibition of CCR7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of ACC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of ACC2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of ACC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of ACC2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of CCR7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:Inhibition of CCR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant His-tagged human KHK expressed in Escherichia coli in presence of NADPHMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Terns Pharmaceuticals
Curated by ChEMBL
Terns Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant FLAG-tagged human DGAT2 expressed in SF9 cells after 1 hr by TopCount assayMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of CCR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of ACC2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of ACC1 (unknown origin)More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Terns Pharmaceuticals
Curated by ChEMBL
Terns Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant FLAG-tagged human DGAT2 expressed in SF9 cells after 1 hr by TopCount assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Terns Pharmaceuticals
Curated by ChEMBL
Terns Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Activation of mouse liver PPARalphaMore data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Inhibition of rat KHKMore data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Inhibition of Dengue virus 4 NS5 full length RdRp activity using RNA as template assessed as inhibition of NTPs incorporation after 90 mins by FAPA a...More data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibition of Dengue virus 2 NS5 full length RdRp activity using RNA as template/primer assessed as inhibition of [alpha3P]GTP incorporation by SDS-P...More data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of recombinant His-tagged human KHK expressed in Escherichia coli in presence of NADPHMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Terns Pharmaceuticals
Curated by ChEMBL
Terns Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 579nMAssay Description:Inhibition of recombinant FLAG-tagged human DGAT2 expressed in SF9 cells after 1 hr by TopCount assayMore data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 minsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Terns Pharmaceuticals
Curated by ChEMBL
Terns Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.15E+3nMAssay Description:Activation of mouse liver PPARalphaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human DNA polymerase-betaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of ACC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of ACC2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.59E+4nMAssay Description:Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 minsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Terns Pharmaceuticals
Curated by ChEMBL
Terns Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.83E+4nMAssay Description:Activation of mouse liver PPARalphaMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human DNA polymerase-betaMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Terns Pharmaceuticals
Curated by ChEMBL
Terns Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of recombinant FLAG-tagged human DGAT1 expressed in SF9 cells after 1 hr by TopCount assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.19E+5nMAssay Description:Inhibition of recombinant His-tagged human KHK expressed in Escherichia coli in presence of NADPHMore data for this Ligand-Target Pair
Affinity DataIC50: 3.19E+5nMAssay Description:Inhibition of recombinant His-tagged human KHK expressed in Escherichia coli in presence of NADPHMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha/Thyroid hormone receptor alpha(Homo sapiens (Human))
Terns Pharmaceuticals
US Patent
Terns Pharmaceuticals
US Patent
Affinity DataEC50: 3.00E+3nMAssay Description:Test compounds were prepared as 10 mM DMSO stock solutions. The stock solution (45 uL) was transferred to a 384-well assay plate, and 3-fold, 10-poin...More data for this Ligand-Target Pair
Ligand Info
TargetRetinoic acid receptor RXR-alpha/Thyroid hormone receptor beta(Homo sapiens (Human))
Terns Pharmaceuticals
US Patent
Terns Pharmaceuticals
US Patent
Affinity DataEC50: 290nMAssay Description:Test compounds were prepared as 10 mM DMSO stock solutions. The stock solution (45 uL) was transferred to a 384-well assay plate, and 3-fold, 10-poin...More data for this Ligand-Target Pair
Ligand Info
TargetRetinoic acid receptor RXR-alpha/Thyroid hormone receptor alpha(Homo sapiens (Human))
Terns Pharmaceuticals
US Patent
Terns Pharmaceuticals
US Patent
Affinity DataEC50: 3.30E+3nMAssay Description:Test compounds were prepared as 10 mM DMSO stock solutions. The stock solution (45 uL) was transferred to a 384-well assay plate, and 3-fold, 10-poin...More data for this Ligand-Target Pair
Ligand Info
TargetRetinoic acid receptor RXR-alpha/Thyroid hormone receptor beta(Homo sapiens (Human))
Terns Pharmaceuticals
US Patent
Terns Pharmaceuticals
US Patent
Affinity DataEC50: 60nMAssay Description:Test compounds were prepared as 10 mM DMSO stock solutions. The stock solution (45 uL) was transferred to a 384-well assay plate, and 3-fold, 10-poin...More data for this Ligand-Target Pair
Ligand Info
TargetRetinoic acid receptor RXR-alpha/Thyroid hormone receptor alpha(Homo sapiens (Human))
Terns Pharmaceuticals
US Patent
Terns Pharmaceuticals
US Patent
Affinity DataEC50: 1.40E+3nMAssay Description:Test compounds were prepared as 10 mM DMSO stock solutions. The stock solution (45 uL) was transferred to a 384-well assay plate, and 3-fold, 10-poin...More data for this Ligand-Target Pair
Ligand Info
TargetRetinoic acid receptor RXR-alpha/Thyroid hormone receptor beta(Homo sapiens (Human))
Terns Pharmaceuticals
US Patent
Terns Pharmaceuticals
US Patent
Affinity DataEC50: 40nMAssay Description:Test compounds were prepared as 10 mM DMSO stock solutions. The stock solution (45 uL) was transferred to a 384-well assay plate, and 3-fold, 10-poin...More data for this Ligand-Target Pair
Ligand Info
TargetRetinoic acid receptor RXR-alpha/Thyroid hormone receptor alpha(Homo sapiens (Human))
Terns Pharmaceuticals
US Patent
Terns Pharmaceuticals
US Patent
Affinity DataEC50: 700nMAssay Description:Test compounds were prepared as 10 mM DMSO stock solutions. The stock solution (45 uL) was transferred to a 384-well assay plate, and 3-fold, 10-poin...More data for this Ligand-Target Pair
Ligand Info
TargetRetinoic acid receptor RXR-alpha/Thyroid hormone receptor beta(Homo sapiens (Human))
Terns Pharmaceuticals
US Patent
Terns Pharmaceuticals
US Patent
Affinity DataEC50: 210nMAssay Description:Test compounds were prepared as 10 mM DMSO stock solutions. The stock solution (45 uL) was transferred to a 384-well assay plate, and 3-fold, 10-poin...More data for this Ligand-Target Pair
Ligand Info
TargetRetinoic acid receptor RXR-alpha/Thyroid hormone receptor alpha(Homo sapiens (Human))
Terns Pharmaceuticals
US Patent
Terns Pharmaceuticals
US Patent
Affinity DataEC50: 3.00E+3nMAssay Description:Test compounds were prepared as 10 mM DMSO stock solutions. The stock solution (45 uL) was transferred to a 384-well assay plate, and 3-fold, 10-poin...More data for this Ligand-Target Pair
Ligand Info
TargetRetinoic acid receptor RXR-alpha/Thyroid hormone receptor beta(Homo sapiens (Human))
Terns Pharmaceuticals
US Patent
Terns Pharmaceuticals
US Patent
Affinity DataEC50: 60nMAssay Description:Test compounds were prepared as 10 mM DMSO stock solutions. The stock solution (45 uL) was transferred to a 384-well assay plate, and 3-fold, 10-poin...More data for this Ligand-Target Pair
Ligand Info
TargetRetinoic acid receptor RXR-alpha/Thyroid hormone receptor alpha(Homo sapiens (Human))
Terns Pharmaceuticals
US Patent
Terns Pharmaceuticals
US Patent
Affinity DataEC50: 900nMAssay Description:Test compounds were prepared as 10 mM DMSO stock solutions. The stock solution (45 uL) was transferred to a 384-well assay plate, and 3-fold, 10-poin...More data for this Ligand-Target Pair
Ligand Info
TargetRetinoic acid receptor RXR-alpha/Thyroid hormone receptor beta(Homo sapiens (Human))
Terns Pharmaceuticals
US Patent
Terns Pharmaceuticals
US Patent
Affinity DataEC50: 30nMAssay Description:Test compounds were prepared as 10 mM DMSO stock solutions. The stock solution (45 uL) was transferred to a 384-well assay plate, and 3-fold, 10-poin...More data for this Ligand-Target Pair
Ligand Info
TargetRetinoic acid receptor RXR-alpha/Thyroid hormone receptor alpha(Homo sapiens (Human))
Terns Pharmaceuticals
US Patent
Terns Pharmaceuticals
US Patent
Affinity DataEC50: 400nMAssay Description:Test compounds were prepared as 10 mM DMSO stock solutions. The stock solution (45 uL) was transferred to a 384-well assay plate, and 3-fold, 10-poin...More data for this Ligand-Target Pair
Ligand Info