Compile Data Set for Download or QSAR
maximum 50k data
Found 172 with Last Name = 'flannery' and Initial = 'cr'
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256157(CHEMBL481894 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  350nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256061(CHEMBL482160 | GNF-Pf-4399 | N-((5-chloro-8-hydrox...)
Affinity DataIC50:  460nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256102(CHEMBL480567 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  490nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256700(2-(N-methyl-N-phenylamino)-N-((5-chloro-8-hydroxyq...)
Affinity DataIC50:  560nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24019(1-benzyl-5-methyl-5'-(4-methylphenyl)-1,2-dihydro-...)
Affinity DataIC50:  610nMAssay Description:ADAMTS-5 activity was determined using a fluorescence resonance energy transfer (FRET) assay using a QF peptide containing an aggrecanase cleavage si...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256062(CHEMBL482170 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  620nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256160(CHEMBL481896 | N-((5-bromo-8-hydroxyquinolin-7-yl)...)
Affinity DataIC50:  620nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24008(1-benzyl-5'-(4-methoxyphenyl)-5-methyl-1,2-dihydro...)
Affinity DataIC50:  640nMpH: 7.5 T: 2°CAssay Description:ADAMTS-5 activity was determined using a fluorescence resonance energy transfer (FRET) assay using a QF peptide containing an aggrecanase cleavage si...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256005(2-(benzyloxy)-N-((5-chloro-8-hydroxyquinolin-7-yl)...)
Affinity DataIC50:  700nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50255999(CHEMBL474607 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  760nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256312(2-(p-tolyloxy)-N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  770nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256660(2-(N-methyl-N-phenylamino)-N-((5-chloro-8-hydroxyq...)
Affinity DataIC50:  780nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24006(5'-(4-methoxyphenyl)-6-propyl-1,2-dihydro-3'H-spir...)
Affinity DataIC50:  780nMpH: 7.5 T: 2°CAssay Description:ADAMTS-5 activity was determined using a fluorescence resonance energy transfer (FRET) assay using a QF peptide containing an aggrecanase cleavage si...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50255970(CHEMBL482073 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  780nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256214(CHEMBL514963 | N-((5-bromo-8-hydroxyquinolin-7-yl)...)
Affinity DataIC50:  800nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256701(2-(N-benzyl-N-methylamino)-N-((5-chloro-8-hydroxyq...)
Affinity DataIC50:  820nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256063(2-(benzyloxy)-N-((5-chloro-8-hydroxyquinolin-7-yl)...)
Affinity DataIC50:  830nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256060(CHEMBL481506 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  830nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256105(CHEMBL482362 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  830nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24007(1-benzyl-5'-(4-methoxyphenyl)-1,2-dihydro-3'H-spir...)
Affinity DataIC50:  870nMpH: 7.5 T: 2°CAssay Description:ADAMTS-5 activity was determined using a fluorescence resonance energy transfer (FRET) assay using a QF peptide containing an aggrecanase cleavage si...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24009(5'-(4-methoxyphenyl)-5-methyl-1-(2-methylphenyl)-1...)
Affinity DataIC50:  900nMpH: 7.5 T: 2°CAssay Description:ADAMTS-5 activity was determined using a fluorescence resonance energy transfer (FRET) assay using a QF peptide containing an aggrecanase cleavage si...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202179(2-(5-(3,4-bis(benzyloxy)benzylidene)-4-oxo-2-thiox...)
Affinity DataIC50:  900nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256313(2-(4-methoxyphenoxy)-N-((5-chloro-8-hydroxyquinoli...)
Affinity DataIC50:  940nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256215(CHEMBL475265 | N-((2-chlorophenyl)(8-hydroxy-5-nit...)
Affinity DataIC50:  940nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24022(1-benzyl-5'-(4-methoxyphenyl)-5-methyl-6-propyl-1,...)
Affinity DataIC50:  950nMAssay Description:ADAMTS-5 activity was determined using a fluorescence resonance energy transfer (FRET) assay using a QF peptide containing an aggrecanase cleavage si...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50255973(CHEMBL475436 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  990nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256059(CHEMBL481505 | GNF-PF-3875 | N-((5-chloro-8-hydrox...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256611(2-(4-cyanophenylamino)-N-((5-chloro-8-hydroxyquino...)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256499(2-(4-chlorophenoxy)-N-((5-chloro-8-hydroxyquinolin...)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256662(2-(4-acetylphenylamino)-N-((5-chloro-8-hydroxyquin...)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202169((R)-2-(5-(3,4-bis(benzyloxy)benzylidene)-4-oxo-2-t...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202186((Z)-5-((5-(4-chlorobenzylthio)-1-methyl-3-(trifluo...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256610(2-(4-acetylphenylamino)-N-((5-chloro-8-hydroxyquin...)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256698(2-(4-chloro-3-methylphenylamino)-N-((5-chloro-8-hy...)
Affinity DataIC50:  1.19E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24013(6-chloro-5'-(4-methoxyphenyl)-1,2-dihydro-3'H-spir...)
Affinity DataIC50:  1.20E+3nMAssay Description:ADAMTS-5 activity was determined using a fluorescence resonance energy transfer (FRET) assay using a QF peptide containing an aggrecanase cleavage si...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24018(5-methyl-1-(2-methylphenyl)-5'-(4-methylphenyl)-1,...)
Affinity DataIC50:  1.20E+3nMAssay Description:ADAMTS-5 activity was determined using a fluorescence resonance energy transfer (FRET) assay using a QF peptide containing an aggrecanase cleavage si...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256158(CHEMBL519950 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  1.21E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256103(CHEMBL482360 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50:  1.22E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256740(2-(N-methyl-N-phenylamino)-N-((5-chloro-8-hydroxyq...)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256661(2-(benzyl(methyl)amino)-N-((5-chloro-8-hydroxyquin...)
Affinity DataIC50:  1.28E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202174((R)-2-(5-(3,4-bis(benzyloxy)benzylidene)-4-oxo-2-t...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202164(2-(5-(3-(3,4-dichlorophenoxy)benzylidene)-4-oxo-2-...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50255974(2-(benzyl(methyl)amino)-N-((5-chloro-8-hydroxyquin...)
Affinity DataIC50:  1.31E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256216(CHEMBL475770 | N-((8-hydroxy-5-methylquinolin-7-yl...)
Affinity DataIC50:  1.32E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50256500(2-(3-(dimethylamino)phenoxy)-N-((5-chloro-8-hydrox...)
Affinity DataIC50:  1.33E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50255969(CHEMBL521273 | N-((8-hydroxy-5-nitroquinolin-7-yl)...)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24001(5'-(4-methylphenyl)-6-propyl-1,2-dihydro-3'H-spiro...)
Affinity DataIC50:  1.40E+3nMpH: 7.5 T: 2°CAssay Description:ADAMTS-5 activity was determined using a fluorescence resonance energy transfer (FRET) assay using a QF peptide containing an aggrecanase cleavage si...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24004(5-ethyl-5'-(4-methoxyphenyl)-1,2-dihydro-3'H-spiro...)
Affinity DataIC50:  1.40E+3nMpH: 7.5 T: 2°CAssay Description:ADAMTS-5 activity was determined using a fluorescence resonance energy transfer (FRET) assay using a QF peptide containing an aggrecanase cleavage si...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24012(5'-(4-methoxyphenyl)-6-methyl-1,2-dihydro-3'H-spir...)
Affinity DataIC50:  1.40E+3nMAssay Description:ADAMTS-5 activity was determined using a fluorescence resonance energy transfer (FRET) assay using a QF peptide containing an aggrecanase cleavage si...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202149(5-(3,5-bis(benzyloxy)benzylidene)-2-thioxothiazoli...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 172 total ) | Next | Last >>
Jump to: