Affinity DataKi: 0.0150nMAssay Description:Inhibition constant of ritonavir towards HIV protease was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.0200nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibition of CYP3A4 (unknown origin) assessed as midazolam 1'- hydroxylationMore data for this Ligand-Target Pair
Affinity DataKi: 66nMAssay Description:Inhibition of CYP3A4 (unknown origin) assessed as midazolam 1'- hydroxylationMore data for this Ligand-Target Pair
Affinity DataKi: 540nMAssay Description:Inhibition of cathepsin D (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of renin (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 4.30E+3nMAssay Description:Inhibition of cathepsin D (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of renin (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibitory concentration against purified recombinant HIV-1 protease using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibitory concentration against purified recombinant HIV-1 protease using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibitory concentration against purified recombinant HIV-1 protease using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibitory concentration against purified recombinant HIV-1 protease using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibitory concentration against purified recombinant HIV-1 protease using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibitory concentration against purified recombinant HIV-1 protease using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibitory concentration against purified recombinant HIV-1 protease using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibitory concentration against purified recombinant HIV-1 protease using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Inhibitory concentration against purified recombinant HIV-1 protease using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories
Abbott Laboratories
Affinity DataIC50: 5nMpH: 4.5 T: 2°CAssay Description:HIV-1 protease inhibition was measured by a fluorescence assay using recombinant HIV-1 protease. The reactions were initiated by the addition of 1 nM...More data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 9.40nMAssay Description:Inhibitory concentration against purified recombinant HIV-1 protease using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 9.60nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibitory concentration against purified recombinant HIV-1 protease using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of HCV1b Con1 NS5B assessed as [3H]UTP incorporation into RNA by scintillation countingMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories
Abbott Laboratories
Affinity DataIC50: 16nMpH: 4.5 T: 2°CAssay Description:HIV-1 protease inhibition was measured by a fluorescence assay using recombinant HIV-1 protease. The reactions were initiated by the addition of 1 nM...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories
Abbott Laboratories
Affinity DataIC50: 16nMpH: 4.5 T: 2°CAssay Description:HIV-1 protease inhibition was measured by a fluorescence assay using recombinant HIV-1 protease. The reactions were initiated by the addition of 1 nM...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of HCV1b Con1 NS5B assessed as [3H]UTP incorporation into RNA by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories
Abbott Laboratories
Affinity DataIC50: 31nMpH: 4.5 T: 2°CAssay Description:HIV-1 protease inhibition was measured by a fluorescence assay using recombinant HIV-1 protease. The reactions were initiated by the addition of 1 nM...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair