TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
G.D. Searle And
Curated by ChEMBL
G.D. Searle And
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:Apparent binding affinity against Candida albicans N-Myristoyltransferase (NMT).More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Candida albicans (Yeast))
G.D. Searle And
Curated by ChEMBL
G.D. Searle And
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:The Compound was tested for the inhibition potency against C. albicans N-myristoyltransferase (NMT) and reported as apparent KiMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
G.D. Searle And
Curated by ChEMBL
G.D. Searle And
Curated by ChEMBL
Affinity DataKi: 70nMAssay Description:Apparent binding affinity against Candida albicans N-Myristoyltransferase (NMT).More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
G.D. Searle And
Curated by ChEMBL
G.D. Searle And
Curated by ChEMBL
Affinity DataKi: 90nMAssay Description:Apparent binding affinity against Human NMT.More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
G.D. Searle And
Curated by ChEMBL
G.D. Searle And
Curated by ChEMBL
Affinity DataKi: 130nMAssay Description:Apparent binding affinity against Candida albicans N-Myristoyltransferase (NMT).More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
G.D. Searle And
Curated by ChEMBL
G.D. Searle And
Curated by ChEMBL
Affinity DataKi: 590nMAssay Description:Apparent binding affinity against Candida albicans N-Myristoyltransferase (NMT).More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
G.D. Searle And
Curated by ChEMBL
G.D. Searle And
Curated by ChEMBL
Affinity DataKi: 760nMAssay Description:Apparent binding affinity against Candida albicans N-Myristoyltransferase (NMT).More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
G.D. Searle And
Curated by ChEMBL
G.D. Searle And
Curated by ChEMBL
Affinity DataKi: 4.20E+3nMAssay Description:Apparent binding affinity against Human NMT.More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Candida albicans (Yeast))
G.D. Searle And
Curated by ChEMBL
G.D. Searle And
Curated by ChEMBL
Affinity DataKi: 1.53E+4nMAssay Description:The Compound was tested for the inhibition potency against C. albicans N-myristoyltransferase (NMT) and reported as apparent KiMore data for this Ligand-Target Pair
Affinity DataIC50: 0.00700nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA)More data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Binding affinity towards alpha V-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA)More data for this Ligand-Target Pair
Affinity DataIC50: 0.190nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA)More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.210nMAssay Description:Inhibition of alphavbeta3 integrin in 293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.270nMAssay Description:Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA)More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.310nMAssay Description:Binding affinity towards alpha V-beta1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMAssay Description:Inhibition of Integrin alphav-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMAssay Description:Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA)More data for this Ligand-Target Pair
Affinity DataIC50: 0.340nMAssay Description:Inhibition of alphavbeta3 integrin in 293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Binding affinity towards alpha V-beta1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.380nMAssay Description:Binding affinity towards alpha V-beta1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.380nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair