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Found 64 with Last Name = 'gademann' and Initial = 'k'
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM50495678(CHEMBL3114822)
Affinity DataKi:  530nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptor expressed in CHO cell membranes after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM50495679(CHEMBL3114826)
Affinity DataKi:  810nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptor expressed in CHO cell membranes after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM50260119(FARINOSONE A)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]CP55,940 from human CB1 receptor expressed in CHOK1 cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260120(CHEMBL4071145)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]CP55,940 from human CB2 receptor expressed in CHOK1 cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM50260118(CHEMBL4086242)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]CP55,940 from human CB1 receptor expressed in CHOK1 cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM50260116(CHEMBL4072432)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]CP55,940 from human CB1 receptor expressed in CHOK1 cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260118(CHEMBL4086242)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]CP55,940 from human CB2 receptor expressed in CHOK1 cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260117(CHEMBL4072884)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]CP55,940 from human CB2 receptor expressed in CHOK1 cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260116(CHEMBL4072432)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]CP55,940 from human CB2 receptor expressed in CHOK1 cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260119(FARINOSONE A)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]CP55,940 from human CB2 receptor expressed in CHOK1 cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM50260120(CHEMBL4071145)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]CP55,940 from human CB1 receptor expressed in CHOK1 cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM50260117(CHEMBL4072884)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]CP55,940 from human CB1 receptor expressed in CHOK1 cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM50321726(CHEMBL1172449 | cyanopeptolin 1020)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of factor 11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM50321726(CHEMBL1172449 | cyanopeptolin 1020)
Affinity DataIC50:  490nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260116(CHEMBL4072432)
Affinity DataIC50:  600nMAssay Description:Inhibition of FAAH in human U937 cells assessed as decrease in [ethanolamine-1-3H]AEA uptake preincubated for 2 mins followed by AEA addition after 5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260117(CHEMBL4072884)
Affinity DataIC50:  700nMAssay Description:Inhibition of FAAH in human U937 cells assessed as decrease in [ethanolamine-1-3H]AEA uptake preincubated for 2 mins followed by AEA addition after 5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260120(CHEMBL4071145)
Affinity DataIC50:  800nMAssay Description:Inhibition of FAAH in human U937 cells assessed as decrease in [ethanolamine-1-3H]AEA uptake preincubated for 2 mins followed by AEA addition after 5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260119(FARINOSONE A)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of FAAH in human U937 cells using [ethanolamine-1-3H]AEA as substrate after 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM50321726(CHEMBL1172449 | cyanopeptolin 1020)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of human tissue plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM50321726(CHEMBL1172449 | cyanopeptolin 1020)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260120(CHEMBL4071145)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of FAAH in human U937 cells using [ethanolamine-1-3H]AEA as substrate after 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260119(FARINOSONE A)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human COX2 preincubated for 15 mins followed by arachidonic acid/2-OG substrate addition after 5 mins by ADHP probe-based f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260118(CHEMBL4086242)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells assessed as decrease in [ethanolamine-1-3H]AEA uptake preincubated for 2 mins followed by AEA addition after 5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260117(CHEMBL4072884)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human COX2 preincubated for 15 mins followed by arachidonic acid/2-OG substrate addition after 5 mins by ADHP probe-based f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260117(CHEMBL4072884)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells assessed as decrease in [ethanolamine-1-3H]AEA uptake preincubated for 2 mins followed by AEA addition after 5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260118(CHEMBL4086242)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human COX2 preincubated for 15 mins followed by arachidonic acid/2-OG substrate addition after 5 mins by ADHP probe-based f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260116(CHEMBL4072432)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human COX2 preincubated for 15 mins followed by arachidonic acid/2-OG substrate addition after 5 mins by ADHP probe-based f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260116(CHEMBL4072432)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells using [ethanolamine-1-3H]AEA as substrate after 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260118(CHEMBL4086242)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells using [ethanolamine-1-3H]AEA as substrate after 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260119(FARINOSONE A)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells using [ethanolamine-1-3H]AEA as substrate after 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260120(CHEMBL4071145)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human COX2 preincubated for 15 mins followed by arachidonic acid/2-OG substrate addition after 5 mins by ADHP probe-based f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of ZüRich

Curated by ChEMBL
LigandPNGBDBM50269614(2-Methyl-beta-carboline-2-ium iodide | 2-methyl-2H...)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition of horse serum BChE by Ellman's reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of ZüRich

Curated by ChEMBL
LigandPNGBDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Affinity DataIC50:  1.69E+4nMAssay Description:Inhibition of horse serum BChE by Ellman's reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of ZüRich

Curated by ChEMBL
LigandPNGBDBM50263009(CHEMBL499836 | Nostacarboline iodide | Nostocarbol...)
Affinity DataIC50:  1.94E+4nMAssay Description:Inhibition of horse serum BChE by Ellman's reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM50321726(CHEMBL1172449 | cyanopeptolin 1020)
Affinity DataIC50: >6.05E+5nMAssay Description:Inhibition of human LMW urokinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CAS_38916-34-6 | CB6417646...)
Affinity DataKd:  0.214nMAssay Description:Binding assay at human somatostatin receptor 3 (hsst3) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50473329(CHEMBL311789)
Affinity DataKd: <1.00E+4nMAssay Description:Binding assay at human somatostatin receptor 2 (hsst2) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 1(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50473329(CHEMBL311789)
Affinity DataKd:  1.32E+4nMAssay Description:Binding assay at human somatostatin receptor 1 (hsst1) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50473330(CHEMBL309948)
Affinity DataKd: <1.00E+4nMAssay Description:Binding assay at human somatostatin receptor 3 (hsst3) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50192018(CHEMBL3350037)
Affinity DataKd:  49nMAssay Description:Binding assay at human somatostatin receptor 5 (hsst5) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50473331(CHEMBL420948)
Affinity DataKd: <1.00E+4nMAssay Description:Binding assay at human somatostatin receptor 3 (hsst3) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50473330(CHEMBL309948)
Affinity DataKd: <1.00E+4nMAssay Description:Binding assay at human somatostatin receptor 4 (hsst4) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 1(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CAS_38916-34-6 | CB6417646...)
Affinity DataKd:  0.832nMAssay Description:Binding assay at human somatostatin receptor 1 (hsst1) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50192018(CHEMBL3350037)
Affinity DataKd:  2.5nMAssay Description:Binding assay at human somatostatin receptor 3 (hsst3) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50473331(CHEMBL420948)
Affinity DataKd: <1.00E+5nMAssay Description:Binding assay at human somatostatin receptor 4 (hsst4) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CAS_38916-34-6 | CB6417646...)
Affinity DataKd:  0.0871nMAssay Description:Binding assay at human somatostatin receptor 2 (hsst2) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 1(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50473330(CHEMBL309948)
Affinity DataKd: <1.00E+5nMAssay Description:Binding assay at human somatostatin receptor 1 (hsst1) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

Curated by ChEMBL
LigandPNGBDBM50072775(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)
Affinity DataKd:  0.590nMAssay Description:Binding affinity to human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50473330(CHEMBL309948)
Affinity DataKd: <1.00E+5nMAssay Description:Binding assay at human somatostatin receptor 2 (hsst2) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50473329(CHEMBL311789)
Affinity DataKd: <1.00E+4nMAssay Description:Binding assay at human somatostatin receptor 5 (hsst5) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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