Affinity DataIC50: 2.80nMAssay Description:Inhibitory activity against recombinant Dihydrofolate reductase from Escherichia coli (ecDHFR)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against dihydrofolate reductase from rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against Dihydrofolate reductase from rat liver (rlDHFR)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory activity of the compound against DHFR (Dihydrofolate reductase) from Rat liverMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from Toxoplasma gondii (tgDHFR)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from Toxoplasma gondii (tgDHFR)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from Toxoplasma gondii (tgDHFR)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from Toxoplasma gondii (tgDHFR)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from Toxoplasma gondii (tgDHFR)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from Toxoplasma gondii (tgDHFR)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from Toxoplasma gondii (tgDHFR)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from Toxoplasma gondii (tgDHFR)More data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibitory activity against recombinant Dihydrofolate reductase from Escherichia coli (ecDHFR)More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibitory concentration against isolated Escherichia coli Dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 7.20nMAssay Description:Inhibitory activity against recombinant Dihydrofolate reductase from Toxoplasma gondii (tgDHFR)More data for this Ligand-Target Pair
Affinity DataIC50: 7.80nMAssay Description:Inhibitory activity against recombinant Dihydrofolate reductase from Escherichia coli (ecDHFR)More data for this Ligand-Target Pair
Affinity DataIC50: 8.10nMAssay Description:Inhibitory activity against recombinant Dihydrofolate reductase from Escherichia coli (ecDHFR)More data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMAssay Description:Inhibitory activity against Dihydrofolate reductase from rat liver (rlDHFR)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against Dihydrofolate reductase from Toxoplasma gondii (tgDHFR)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against recombinant Dihydrofolate reductase from Escherichia coli (ecDHFR)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against dihydrofolate reductase from Toxoplasma gondiiMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against recombinant Dihydrofolate reductase from Escherichia coli (ecDHFR)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibitory activity of the compound against DHFR (Dihydrofolate reductase) from Toxoplasma gondii.More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against Dihydrofolate reductase from recombinant human (hDHFR)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibitory activity of the compound against DHFR (Dihydrofolate reductase) from Toxoplasma gondii.More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibitory activity of the compound against DHFR (Dihydrofolate reductase) from Mycobacterium aviumMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibitory activity against recombinant Dihydrofolate reductase from Escherichia coli (ecDHFR)More data for this Ligand-Target Pair
Affinity DataIC50: 13.8nMAssay Description:Inhibitory concentration against isolated Pneumocystis carinii DHFR (Dihydrofolate reductase)More data for this Ligand-Target Pair
Affinity DataIC50: 14.5nMAssay Description:Inhibitory concentration against isolated human Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against Dihydrofolate reductase from Pneumocystis carinii (pcDHFR)More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against Dihydrofolate reductase from rat liver (rlDHFR)More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibitory activity of the compound against DHFR (Dihydrofolate reductase) from Mycobacterium aviumMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against recombinant Dihydrofolate reductase from Escherichia coli (ecDHFR)More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibitory activity against Dihydrofolate reductase from rat liver (rlDHFR)More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration against isolated Escherichia coli Dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against Dihydrofolate reductase from Toxoplasma gondii (tgDHFR)More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against Dihydrofolate reductase from Lactobacillus casei (lcDHFR)More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against Dihydrofolate reductase from Lactobacillus casei (lcDHFR)More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibitory concentration against isolated Toxoplasma gondii DHFR (dihydrofolate reductase)More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against Dihydrofolate reductase from Pneumocystis carinii (pcDHFR)More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibitory concentration against isolated Lactobacillus casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against Dihydrofolate reductase from rat liver (rlDHFR)More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibitory activity of the compound against DHFR (Dihydrofolate reductase) from Rat liverMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against Dihydrofolate reductase from Toxoplasma gondii (tgDHFR)More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against Dihydrofolate reductase from Toxoplasma gondii (tgDHFR)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibitory activity against Dihydrofolate reductase from Toxoplasma gondii (tgDHFR)More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibitory activity of the compound against DHFR (Dihydrofolate reductase) from Mycobacterium aviumMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibitory activity of the compound against DHFR (Dihydrofolate reductase) from Toxoplasma gondii.More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibitory activity against Dihydrofolate reductase from Lactobacillus casei ( lcDHFR)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibitory activity against Dihydrofolate reductase from Toxoplasma gondii (tgDHFR)More data for this Ligand-Target Pair