Affinity DataKi: 5nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: 79nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: 93nMAssay Description:Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: 138nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: 158nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: 158nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+3nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
Affinity DataKi: 7.40E+3nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of GST tagged PERK cytoplasmic domain mediated EIF2alpha phosphorylationMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of GST tagged PERK cytoplasmic domain mediated EIF2alpha phosphorylationMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of GST tagged PERK cytoplasmic domain mediated EIF2alpha phosphorylationMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of GST tagged PERK cytoplasmic domain mediated EIF2alpha phosphorylationMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of GST tagged PERK cytoplasmic domain mediated EIF2alpha phosphorylationMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of GST tagged PERK cytoplasmic domain mediated EIF2alpha phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.330nMAssay Description:Inhibition of recombinant human cathepsin K in a fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Inhibition of recombinant human cathepsin K in a fluorescence assayMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of GST tagged PERK cytoplasmic domain mediated EIF2alpha phosphorylationMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of GST-tagged PERK cytoplasmic domain (536 to 1116) (unknown origin) assessed as biotinylated His6-tagged EIF2alpha phosphorylation preinc...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of GST tagged PERK cytoplasmic domain mediated EIF2alpha phosphorylationMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of GST tagged PERK cytoplasmic domain mediated EIF2alpha phosphorylationMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of GST-tagged PERK cytoplasmic domain (536 to 1116) (unknown origin) assessed as biotinylated His6-tagged EIF2alpha phosphorylation preinc...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of GST-tagged PERK cytoplasmic domain (536 to 1116) (unknown origin) assessed as biotinylated His6-tagged EIF2alpha phosphorylation preinc...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant human cathepsin K in a fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of GST tagged PERK cytoplasmic domain mediated EIF2alpha phosphorylationMore data for this Ligand-Target Pair