Compile Data Set for Download or QSAR
maximum 50k data
Found 516 with Last Name = 'goble' and Initial = 'sd'
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257994((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...)
Affinity DataIC50:  0.100nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257994((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...)
Affinity DataIC50:  0.100nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257994((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...)
Affinity DataIC50:  0.100nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257995((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(3-et...)
Affinity DataIC50:  0.300nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258046((1S,3R)-N-(3,5-bis(trifluoromethyl)benz yl)-3-(3-f...)
Affinity DataIC50:  0.800nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258046((1S,3R)-N-(3,5-bis(trifluoromethyl)benz yl)-3-(3-f...)
Affinity DataIC50:  0.800nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258090((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50231610((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(4-(4...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of CCR5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50374521(CHEMBL272369)
Affinity DataIC50:  1.40nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257994((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...)
Affinity DataIC50:  1.5nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257994((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...)
Affinity DataIC50:  1.5nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50231615((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at CCR2 receptor in human monocytes assessed as inhibition of MCP1-mediated chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50231619((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-(2-hy...)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at CCR2 receptor in human monocytes assessed as inhibition of MCP1-mediated chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50311121(CHEMBL1079108 | N-(4-(2-amino-2-methylpropyl)pheny...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human GHS-R1aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50374523(CHEMBL402532)
Affinity DataIC50:  2.5nMAssay Description:Antagonist activity at human CCR2 assessed as inhibition of MCP1-induced monocyte chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257995((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(3-et...)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257995((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(3-et...)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257995((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(3-et...)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50231620((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(4-(4...)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257841((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)
Affinity DataIC50:  3.30nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257994((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...)
Affinity DataIC50:  4nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50231613(CHEMBL258246 | N-(3,5-bis(trifluoromethyl)benzyl)-...)
Affinity DataIC50:  4nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50374523(CHEMBL402532)
Affinity DataIC50:  4.60nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257898((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)
Affinity DataIC50:  4.60nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50231615((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)
Affinity DataIC50:  5nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50231615((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)
Affinity DataIC50:  5nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258043((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)
Affinity DataIC50:  5.10nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258090((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)
Affinity DataIC50:  5.5nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50231614(CHEMBL403033 | N-(3,5-bis(trifluoromethyl)benzyl)-...)
Affinity DataIC50:  6nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258046((1S,3R)-N-(3,5-bis(trifluoromethyl)benz yl)-3-(3-f...)
Affinity DataIC50:  6nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50231612(CHEMBL255513 | N-(3,5-bis(trifluoromethyl)benzyl)-...)
Affinity DataIC50:  6nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50231611(CHEMBL255312 | N-(3,5-bis(trifluoromethyl)benzyl)-...)
Affinity DataIC50:  6nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50231619((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-(2-hy...)
Affinity DataIC50:  6nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258143((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(3,5-...)
Affinity DataIC50:  7nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258043((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)
Affinity DataIC50:  7.80nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50311117(CHEMBL1078900 | N-(4-(2-amino-2-methylpropyl)pheny...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human GHS-R1aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257841((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)
Affinity DataIC50:  8.60nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257841((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)
Affinity DataIC50:  8.60nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50311092((S)-4-(3-hexylureido)-N-(4-(2-(2-hydroxy-3-(4-hydr...)
Affinity DataIC50:  13nMAssay Description:Displacement of [35S]MK0677 from human GHS-R1aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50311116(CHEMBL1078899 | N-(4-(2-amino-2-methylpropyl)pheny...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human GHS-R1aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50311119(CHEMBL1079091 | N-(4-(2-amino-2-methylpropyl)pheny...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human GHS-R1aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50231620((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(4-(4...)
Affinity DataIC50:  16nMAssay Description:Displacement of [33S]MK499 from human ERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50311120(CHEMBL1079107 | N-(4-(2-amino-2-methylpropyl)pheny...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human GHS-R1aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257900((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)
Affinity DataIC50:  22nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50231618(CHEMBL401608 | N-(3,5-bis(trifluoromethyl)benzyl)-...)
Affinity DataIC50:  24nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258092((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)
Affinity DataIC50:  28nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)
Affinity DataIC50:  28nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50311118(CHEMBL1078982 | N-(4-(2-amino-2-methylpropyl)pheny...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human GHS-R1aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257899((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)
Affinity DataIC50:  30nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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