Affinity DataKi: 0.0900nMAssay Description:Inhibition of [3H]DAGO binding to rat brain membrane Opioid receptor mu 1More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:In vitro inhibitory potency for preventing ET-1 induced constriction of rat aortic rings (ETA receptor)More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 0.25nMAssay Description:Inhibition of [3H]diprenorphine binding to rat brain membrane opioid receptors;(T= total opioid receptor family)More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 0.310nMAssay Description:In vitro inhibitory potency for preventing sarafotoxin S6c induced constriction of rat tracheal rings (ETB receptor)More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Inhibition of [3H]diprenorphine binding to rat brain membrane opioid receptors;(T= total opioid receptor family)More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of [3H]DAGO binding to rat brain membrane Opioid receptor mu 1More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 0.550nMAssay Description:Inhibition of [3H]diprenorphine binding to rat brain membrane opioid receptors;(T= total opioid receptor family)More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of [3H]DAGO binding to rat brain membrane Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Opioid receptor delta 1 apparent binding constant from rat brain membranes using [3H]DADLE binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of [3H]DAGO binding to rat brain membrane Opioid receptor mu 1More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Inhibition of [3H]diprenorphine binding to rat brain membrane opioid receptors;(T= total opioid receptor family)More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Opioid receptor delta 1 apparent binding constant from rat brain membranes using [3H]DADLE binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Opioid receptor kappa 1 apparent binding constant from guinea pig cerebellum using [3H]diprenorphine binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Opioid receptor kappa 1 apparent binding constant from guinea pig cerebellum using [3H]diprenorphine binding assayMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Inhibition of [3H]diprenorphine binding to rat brain membrane opioid receptors;(T= total opioid receptor family)More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Inhibition of [3H]DAGO binding to rat brain membrane Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of [3H]DAGO binding to rat brain membrane Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of [3H]DAGO binding to rat brain membrane Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of [3H]DAGO binding to rat brain membrane Opioid receptor mu 1More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Inhibition of [3H]diprenorphine binding to rat brain membrane opioid receptors;(T= total opioid receptor family)More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Inhibition of [3H]diprenorphine binding to rat brain membrane opioid receptors;(T= total opioid receptor family)More data for this Ligand-Target Pair
Affinity DataKi: 6.70nMAssay Description:Opioid receptor delta 1 apparent binding constant from rat brain membranes using [3H]DADLE binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.10nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of [3H]DAGO binding to rat brain membrane Opioid receptor mu 1More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Inhibition of [3H]diprenorphine binding to rat brain membrane opioid receptors;(T= total opioid receptor family)More data for this Ligand-Target Pair
Affinity DataKi: 8.70nMAssay Description:Opioid receptor kappa 1 apparent binding constant from guinea pig cerebellum using [3H]diprenorphine binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Opioid receptor kappa 1 apparent binding constant from rat brain membranes using [3H]DADLE binding assayMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibition of [3H]diprenorphine binding to rat brain membrane opioid receptors;(T= total opioid receptor family)More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
University Of Strasburg
Curated by ChEMBL
University Of Strasburg
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [3H]ifenprodil from rat brain membrane NR2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of [3H]DAGO binding to rat brain membrane Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of [3H]DAGO binding to rat brain membrane Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 13.8nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:In vitro inhibitory potency for preventing ET-1 induced constriction of rat aortic rings (ETA receptor)More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Inhibition of [3H]diprenorphine binding to rat brain membrane opioid receptors;(T= total opioid receptor family)More data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...More data for this Ligand-Target Pair
Affinity DataKi: 24.2nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...More data for this Ligand-Target Pair
Affinity DataKi: 26.8nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Inhibition of [3H]diprenorphine binding to rat brain membrane opioid receptors;(T= total opioid receptor family)More data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...More data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:Inhibition of [3H]DAGO binding to rat brain membrane Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 47.6nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
University Of Strasburg
Curated by ChEMBL
University Of Strasburg
Curated by ChEMBL
Affinity DataKi: 58nMAssay Description:Displacement of [3H]ifenprodil from rat brain membrane NR2B receptorMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
University Of Strasburg
Curated by ChEMBL
University Of Strasburg
Curated by ChEMBL
Affinity DataKi: 62nMAssay Description:Displacement of [3H]ifenprodil from rat brain membrane NR2B receptorMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 62nMAssay Description:Inhibition of [3H]diprenorphine binding to rat brain membrane opioid receptors;(T= total opioid receptor family)More data for this Ligand-Target Pair
Affinity DataKi: 64.3nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...More data for this Ligand-Target Pair
Affinity DataKi: 75nMAssay Description:Opioid receptor delta 1 apparent binding constant from rat brain membranes using [3H]DADLE binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 92nMAssay Description:Opioid receptor kappa 1 apparent binding constant from guinea pig cerebellum using [3H]diprenorphine binding assayMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
University Of Strasburg
Curated by ChEMBL
University Of Strasburg
Curated by ChEMBL
Affinity DataKi: 97nMAssay Description:Displacement of [3H]ifenprodil from rat brain membrane NR2B receptorMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
University Of Strasburg
Curated by ChEMBL
University Of Strasburg
Curated by ChEMBL
Affinity DataKi: 97nMAssay Description:Displacement of [3H]ifenprodil from rat brain membrane NR2B receptorMore data for this Ligand-Target Pair