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Found 119 with Last Name = 'gonzalez pacanowska' and Initial = 'd'
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataKi:  0.0380nMAssay Description:Inhibitory activity against Trypanosoma cruzi dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50077798(2-{4-[(3-Carboxy-propyl)-(2,4-diamino-pteridin-6-y...)
Affinity DataKi:  0.107nMAssay Description:Inhibitory activity against Trypanosoma cruzi dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50077796(2-{4-[(4-Carboxy-butyl)-(2,4-diamino-pteridin-6-yl...)
Affinity DataKi:  0.131nMAssay Description:Inhibitory activity against Trypanosoma cruzi dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataKi:  0.179nMAssay Description:Inhibitory activity against dihydrofolate reductase in humansMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50077799(2-{4-[(5-Carboxy-pentyl)-(2,4-diamino-pteridin-6-y...)
Affinity DataKi:  0.183nMAssay Description:Inhibitory activity against Trypanosoma cruzi dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50077796(2-{4-[(4-Carboxy-butyl)-(2,4-diamino-pteridin-6-yl...)
Affinity DataKi:  1.5nMAssay Description:Inhibitory activity against dihydrofolate reductase in humansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50077799(2-{4-[(5-Carboxy-pentyl)-(2,4-diamino-pteridin-6-y...)
Affinity DataKi:  1.60nMAssay Description:Inhibitory activity against Trypanosoma cruzi dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50077798(2-{4-[(3-Carboxy-propyl)-(2,4-diamino-pteridin-6-y...)
Affinity DataKi:  2nMAssay Description:Inhibitory activity against dihydrofolate reductase in humansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50077794(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-(3-ethoxyc...)
Affinity DataKi:  14nMAssay Description:Inhibitory activity against Trypanosoma cruzi dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50077797(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-(4-ethoxyc...)
Affinity DataKi:  46nMAssay Description:Inhibitory activity against Trypanosoma cruzi dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50077795(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-(5-ethoxyc...)
Affinity DataKi:  56nMAssay Description:Inhibitory activity against Trypanosoma cruzi dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Trypanosoma cruzi)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50052351(3-Biphenyl-4-yl-1-aza-bicyclo[2.2.2]octan-3-ol | 3...)
Affinity DataKi:  62nMAssay Description:Inhibition of Trypanosoma cruzi squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50077794(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-(3-ethoxyc...)
Affinity DataKi:  133nMAssay Description:Inhibitory activity against dihydrofolate reductase in humansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50077797(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-(4-ethoxyc...)
Affinity DataKi:  453nMAssay Description:Inhibitory activity against dihydrofolate reductase in humansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50077795(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-(5-ethoxyc...)
Affinity DataKi:  485nMAssay Description:Inhibitory activity against dihydrofolate reductase in humansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM8136(N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-{pyrazolo[1...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human GSK3beta using biotinylated-aminohexyl-Ala-Ala-Ala-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser(PO3)-Tyr-Arg-amide as substrate af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM8146(N-(3,5-dimethylphenyl)-4-{pyrazolo[1,5-a]pyridazin...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human GSK3beta using biotinylated-aminohexyl-Ala-Ala-Ala-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser(PO3)-Tyr-Arg-amide as substrate af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM8128(N-(3-methoxyphenyl)-4-{pyrazolo[1,5-a]pyridazin-3-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human CDK2 using biotinylated-aminohexyl-Ala-Ala-Ala-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser(PO3)-Tyr-Arg-amide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM8137(N-(3,4-difluorophenyl)-4-{pyrazolo[1,5-a]pyridazin...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human CDK2 using biotinylated-aminohexyl-Ala-Ala-Ala-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser(PO3)-Tyr-Arg-amide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM8146(N-(3,5-dimethylphenyl)-4-{pyrazolo[1,5-a]pyridazin...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human CDK2 using biotinylated-aminohexyl-Ala-Ala-Ala-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser(PO3)-Tyr-Arg-amide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM8126(N-phenyl-4-{pyrazolo[1,5-a]pyridazin-3-yl}pyrimidi...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human CDK2 using biotinylated-aminohexyl-Ala-Ala-Ala-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser(PO3)-Tyr-Arg-amide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM8136(N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-{pyrazolo[1...)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of human CDK2 using biotinylated-aminohexyl-Ala-Ala-Ala-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser(PO3)-Tyr-Arg-amide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM8128(N-(3-methoxyphenyl)-4-{pyrazolo[1,5-a]pyridazin-3-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human GSK3beta using biotinylated-aminohexyl-Ala-Ala-Ala-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser(PO3)-Tyr-Arg-amide as substrate af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM8137(N-(3,4-difluorophenyl)-4-{pyrazolo[1,5-a]pyridazin...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human GSK3beta using biotinylated-aminohexyl-Ala-Ala-Ala-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser(PO3)-Tyr-Arg-amide as substrate af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50506295(GW801372X)
Affinity DataIC50:  13nMAssay Description:Inhibition of human GSK3beta using biotinylated-aminohexyl-Ala-Ala-Ala-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser(PO3)-Tyr-Arg-amide as substrate af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSqualene synthase(Leishmania major)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50208574((R)-3-((2-benzyl-6-((3R,4S)-3-hydroxy-4-methoxypyr...)
Affinity DataIC50:  13nMAssay Description:Inhibition of Leishmania major recombinant squalene synthase expressed in Escherichia coli by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Leishmania major)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50052351(3-Biphenyl-4-yl-1-aza-bicyclo[2.2.2]octan-3-ol | 3...)
Affinity DataIC50:  13nMAssay Description:Inhibition of Leishmania major recombinant squalene synthase expressed in Escherichia coli by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50506295(GW801372X)
Affinity DataIC50:  16nMAssay Description:Inhibition of human CDK2 using biotinylated-aminohexyl-Ala-Ala-Ala-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser(PO3)-Tyr-Arg-amide as substrate after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM8126(N-phenyl-4-{pyrazolo[1,5-a]pyridazin-3-yl}pyrimidi...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human GSK3beta using biotinylated-aminohexyl-Ala-Ala-Ala-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser(PO3)-Tyr-Arg-amide as substrate af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50506295(GW801372X)
Affinity DataIC50:  20nMAssay Description:Inhibition of human CDK4 using biotinylated-aminohexyl-Ala-Ala-Ala-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser(PO3)-Tyr-Arg-amide as substrate after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCycloartenol-C-24-methyltransferase(Arabidopsis thaliana)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50409741(CHEMBL2069130)
Affinity DataIC50:  28nMAssay Description:In vitro inhibitory concentration against L. major Sterol 24-C-methyltransferase (24-SMT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Leishmania major)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50208577((R)-3-((2-benzyl-6-(3-methoxypropoxy)pyridin-3-yl)...)
Affinity DataIC50:  33nMAssay Description:Inhibition of Leishmania major recombinant squalene synthase expressed in Escherichia coli by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM8197(4-{6-methyl-2-phenylpyrazolo[1,5-a]pyridazin-3-yl}...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human GSK3beta using biotinylated-aminohexyl-Ala-Ala-Ala-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser(PO3)-Tyr-Arg-amide as substrate af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM8133(N-(4-tert-butylphenyl)-4-{pyrazolo[1,5-a]pyridazin...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human GSK3beta using biotinylated-aminohexyl-Ala-Ala-Ala-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser(PO3)-Tyr-Arg-amide as substrate af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM8152(4-{6-methoxypyrazolo[1,5-a]pyridazin-3-yl}-N-[3-(t...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human GSK3beta using biotinylated-aminohexyl-Ala-Ala-Ala-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser(PO3)-Tyr-Arg-amide as substrate af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM8189(N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-{2-[3-(trif...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human GSK3beta using biotinylated-aminohexyl-Ala-Ala-Ala-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser(PO3)-Tyr-Arg-amide as substrate af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM8128(N-(3-methoxyphenyl)-4-{pyrazolo[1,5-a]pyridazin-3-...)
Affinity DataIC50:  63nMAssay Description:Inhibition of human CDK4 using biotinylated-aminohexyl-Ala-Ala-Ala-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser(PO3)-Tyr-Arg-amide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCycloartenol-C-24-methyltransferase(Arabidopsis thaliana)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50134737((3S,10S,13S,17S)-17-(1-Hydroxy-1-piperidin-3-yl-et...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibitory concentration against L. major Sterol 24-C-methyltransferase (24-SMT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Leishmania major)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50270321(3-[1'-{4'-(Benzyloxy)-phenyl}]-quinuclidine-2-ene ...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Leishmania major recombinant squalene synthase expressed in Escherichia coli by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM8133(N-(4-tert-butylphenyl)-4-{pyrazolo[1,5-a]pyridazin...)
Affinity DataIC50:  158nMAssay Description:Inhibition of human CDK2 using biotinylated-aminohexyl-Ala-Ala-Ala-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser(PO3)-Tyr-Arg-amide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM8126(N-phenyl-4-{pyrazolo[1,5-a]pyridazin-3-yl}pyrimidi...)
Affinity DataIC50:  158nMAssay Description:Inhibition of human CDK4 using biotinylated-aminohexyl-Ala-Ala-Ala-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser(PO3)-Tyr-Arg-amide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Leishmania major)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50208573(3-[1'-{4'-(Ethoxycarbonyl)-phenyl}]-quinuclidine-2...)
Affinity DataIC50:  180nMAssay Description:Inhibition of Leishmania major recombinant squalene synthase expressed in Escherichia coli by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM8152(4-{6-methoxypyrazolo[1,5-a]pyridazin-3-yl}-N-[3-(t...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human CDK2 using biotinylated-aminohexyl-Ala-Ala-Ala-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser(PO3)-Tyr-Arg-amide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50270321(3-[1'-{4'-(Benzyloxy)-phenyl}]-quinuclidine-2-ene ...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli BL21(DE3 pLysS) by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM8136(N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-{pyrazolo[1...)
Affinity DataIC50:  316nMAssay Description:Inhibition of human CDK4 using biotinylated-aminohexyl-Ala-Ala-Ala-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser(PO3)-Tyr-Arg-amide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Leishmania major)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50270302(3-[7'-(Methoxy)-napht-2'-yl]-quinuclidine-2-ene | ...)
Affinity DataIC50:  490nMAssay Description:Inhibition of Leishmania major recombinant squalene synthase expressed in Escherichia coli by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50269921(3-[1'-{2'-(4''-Ethyl ethanoatephenyl)-ethynyl]-3-q...)
Affinity DataIC50:  660nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli BL21(DE3 pLysS) by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Leishmania major)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50269921(3-[1'-{2'-(4''-Ethyl ethanoatephenyl)-ethynyl]-3-q...)
Affinity DataIC50:  970nMAssay Description:Inhibition of Leishmania major recombinant squalene synthase expressed in Escherichia coli by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Leishmania major)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50269938(3-[1'-2'-(2''-Pyrazinyl)}-ethynyl]-3-quinuclidinol...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Leishmania major recombinant squalene synthase expressed in Escherichia coli by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Leishmania major)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50269937(3-[1'-2'-(4''-Hydroxy-3''-benzoic acid)}-ethynyl]-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Leishmania major recombinant squalene synthase expressed in Escherichia coli by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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