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Found 55 with Last Name = 'govender' and Initial = 't'
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50485187(CHEMBL2035872)
Affinity DataKi:  1.20nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50485183(CHEMBL2034991)
Affinity DataIC50:  0.170nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM13934(Atazanavir | BMS 232632 | CGP 73547 | CHEMBL1163 |...)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 subtype C protease expressed in Escherichia coli BL21 assessed as hydrolysis of substrate using chromogenic substrate Lys-Ala-Arg-...More data for this Ligand-Target Pair
TargetHIV-1 protease(Human immunodeficiency virus)
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM13934(Atazanavir | BMS 232632 | CGP 73547 | CHEMBL1163 |...)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 subtype C protease Q7K mutant expressed in Escherichia coli BL21 (DE3) pLysS using Lys-Ala-Arg-Val-Nle-p-nitro-Phe-Glu-Ala-Nle-NH2...More data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM13934(Atazanavir | BMS 232632 | CGP 73547 | CHEMBL1163 |...)
Affinity DataIC50:  4nMAssay Description:Inhibition of South African HIV1 subtype C protease expressed in Escherichia coli BL21S4 (DE3)pLysS cells using Lys-Ala-Arg-Val-Nle-p-nitro-Phe-Glu-A...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50611418(CHEMBL5271655)
Affinity DataIC50:  20nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50180655(A-157378-0 | A-157378.0 | ABT-378 | CHEBI:31781 | ...)
Affinity DataIC50:  25nMAssay Description:Inhibition of South African HIV1 subtype C protease expressed in Escherichia coli BL21S4 (DE3)pLysS cells using Lys-Ala-Arg-Val-Nle-p-nitro-Phe-Glu-A...More data for this Ligand-Target Pair
TargetHIV-1 protease(Human immunodeficiency virus)
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50180655(A-157378-0 | A-157378.0 | ABT-378 | CHEBI:31781 | ...)
Affinity DataIC50:  25nMAssay Description:Inhibition of HIV1 subtype C protease Q7K mutant expressed in Escherichia coli BL21 (DE3) pLysS using Lys-Ala-Arg-Val-Nle-p-nitro-Phe-Glu-Ala-Nle-NH2...More data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50180655(A-157378-0 | A-157378.0 | ABT-378 | CHEBI:31781 | ...)
Affinity DataIC50:  25nMAssay Description:Inhibition of HIV1 subtype C protease expressed in Escherichia coli BL21 assessed as hydrolysis of substrate using chromogenic substrate Lys-Ala-Arg-...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50611421(CHEMBL5276637)
Affinity DataIC50:  70nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHIV-1 protease(Human immunodeficiency virus)
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50483620(CHEMBL1761675)
Affinity DataIC50:  78nMAssay Description:Inhibition of HIV1 subtype C protease Q7K mutant expressed in Escherichia coli BL21 (DE3) pLysS using Lys-Ala-Arg-Val-Nle-p-nitro-Phe-Glu-Ala-Nle-NH2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50483620(CHEMBL1761675)
Affinity DataIC50:  78nMAssay Description:Inhibition of HIV1 subtype C protease expressed in Escherichia coli BL21 assessed as hydrolysis of substrate using chromogenic substrate Lys-Ala-Arg-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50611421(CHEMBL5276637)
Affinity DataIC50:  160nMAssay Description:Inhibition of CDK5/p25 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHIV-1 protease(Human immunodeficiency virus)
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50483627(CHEMBL1761678)
Affinity DataIC50:  500nMAssay Description:Inhibition of HIV1 subtype C protease Q7K mutant expressed in Escherichia coli BL21 (DE3) pLysS using Lys-Ala-Arg-Val-Nle-p-nitro-Phe-Glu-Ala-Nle-NH2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHIV-1 protease(Human immunodeficiency virus)
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50484277(CHEMBL1829140)
Affinity DataIC50:  500nMAssay Description:Inhibition of HIV1 subtype C protease Q7K mutant expressed in Escherichia coli BL21 (DE3) pLysS using Lys-Ala-Arg-Val-Nle-p-nitro-Phe-Glu-Ala-Nle-NH2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHIV-1 protease(Human immunodeficiency virus)
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50484277(CHEMBL1829140)
Affinity DataIC50:  500nMAssay Description:Inhibition of HIV1 subtype C protease Q7K mutant expressed in Escherichia coli BL21 (DE3) pLysS using Lys-Ala-Arg-Val-Nle-p-nitro-Phe-Glu-Ala-Nle-NH2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50483622(CHEMBL1761681)
Affinity DataIC50:  500nMAssay Description:Inhibition of HIV1 subtype C protease expressed in Escherichia coli BL21 assessed as hydrolysis of substrate using chromogenic substrate Lys-Ala-Arg-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50483627(CHEMBL1761678)
Affinity DataIC50:  500nMAssay Description:Inhibition of HIV1 subtype C protease expressed in Escherichia coli BL21 assessed as hydrolysis of substrate using chromogenic substrate Lys-Ala-Arg-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50485185(CHEMBL2035871)
Affinity DataIC50:  710nMAssay Description:Inhibition of South African HIV1 subtype C protease expressed in Escherichia coli BL21S4 (DE3)pLysS cells using Lys-Ala-Arg-Val-Nle-p-nitro-Phe-Glu-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50485186(CHEMBL2035868)
Affinity DataIC50:  760nMAssay Description:Inhibition of South African HIV1 subtype C protease expressed in Escherichia coli BL21S4 (DE3)pLysS cells using Lys-Ala-Arg-Val-Nle-p-nitro-Phe-Glu-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50485180(CHEMBL2035865)
Affinity DataIC50:  950nMAssay Description:Inhibition of South African HIV1 subtype C protease expressed in Escherichia coli BL21S4 (DE3)pLysS cells using Lys-Ala-Arg-Val-Nle-p-nitro-Phe-Glu-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50485188(CHEMBL2035866)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of South African HIV1 subtype C protease expressed in Escherichia coli BL21S4 (DE3)pLysS cells using Lys-Ala-Arg-Val-Nle-p-nitro-Phe-Glu-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50485181(CHEMBL2035867)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of South African HIV1 subtype C protease expressed in Escherichia coli BL21S4 (DE3)pLysS cells using Lys-Ala-Arg-Val-Nle-p-nitro-Phe-Glu-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50485191(CHEMBL2035863)
Affinity DataIC50:  1.09E+3nMAssay Description:Inhibition of South African HIV1 subtype C protease expressed in Escherichia coli BL21S4 (DE3)pLysS cells using Lys-Ala-Arg-Val-Nle-p-nitro-Phe-Glu-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50485189(CHEMBL2035864)
Affinity DataIC50:  1.29E+3nMAssay Description:Inhibition of South African HIV1 subtype C protease expressed in Escherichia coli BL21S4 (DE3)pLysS cells using Lys-Ala-Arg-Val-Nle-p-nitro-Phe-Glu-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))TBA
LigandPNGBDBM153386(2-(4,5-Dibromo-1H-pyrrole-2-carbonyl)-N-(4-chlorop...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of MMP-2 (unknown origin) using succinylated gelatin as substrate incubated for 80 mins by microplate readerMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50483621(CHEMBL1761679)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of HIV1 subtype C protease expressed in Escherichia coli BL21 assessed as hydrolysis of substrate using chromogenic substrate Lys-Ala-Arg-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHIV-1 protease(Human immunodeficiency virus)
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50483621(CHEMBL1761679)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of HIV1 subtype C protease Q7K mutant expressed in Escherichia coli BL21 (DE3) pLysS using Lys-Ala-Arg-Val-Nle-p-nitro-Phe-Glu-Ala-Nle-NH2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50483625(CHEMBL1761680)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of HIV1 subtype C protease expressed in Escherichia coli BL21 assessed as hydrolysis of substrate using chromogenic substrate Lys-Ala-Arg-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHIV-1 protease(Human immunodeficiency virus)
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50483625(CHEMBL1761680)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of HIV1 subtype C protease Q7K mutant expressed in Escherichia coli BL21 (DE3) pLysS using Lys-Ala-Arg-Val-Nle-p-nitro-Phe-Glu-Ala-Nle-NH2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50483624(CHEMBL1761682)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of HIV1 subtype C protease expressed in Escherichia coli BL21 assessed as hydrolysis of substrate using chromogenic substrate Lys-Ala-Arg-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50485182(CHEMBL2035869)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of South African HIV1 subtype C protease expressed in Escherichia coli BL21S4 (DE3)pLysS cells using Lys-Ala-Arg-Val-Nle-p-nitro-Phe-Glu-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHIV-1 protease(Human immunodeficiency virus)
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50483623(CHEMBL1761677)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HIV1 subtype C protease Q7K mutant expressed in Escherichia coli BL21 (DE3) pLysS using Lys-Ala-Arg-Val-Nle-p-nitro-Phe-Glu-Ala-Nle-NH2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHIV-1 protease(Human immunodeficiency virus)
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50483626(CHEMBL1761676)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of HIV1 subtype C protease Q7K mutant expressed in Escherichia coli BL21 (DE3) pLysS using Lys-Ala-Arg-Val-Nle-p-nitro-Phe-Glu-Ala-Nle-NH2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50483623(CHEMBL1761677)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HIV1 subtype C protease expressed in Escherichia coli BL21 assessed as hydrolysis of substrate using chromogenic substrate Lys-Ala-Arg-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50485190(CHEMBL2035870)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of South African HIV1 subtype C protease expressed in Escherichia coli BL21S4 (DE3)pLysS cells using Lys-Ala-Arg-Val-Nle-p-nitro-Phe-Glu-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50483626(CHEMBL1761676)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of HIV1 subtype C protease expressed in Escherichia coli BL21 assessed as hydrolysis of substrate using chromogenic substrate Lys-Ala-Arg-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)TBA
LigandPNGBDBM50611428(CHEMBL5287845)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent ubiquitination in presence of ATP measured after 13 hrs by fluorescenc...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)TBA
LigandPNGBDBM50611427(CHEMBL5279459)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent ubiquitination in presence of ATP measured after 13 hrs by fluorescenc...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)TBA
LigandPNGBDBM50611426(CHEMBL5267416)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent ubiquitination in presence of ATP measured after 13 hrs by fluorescenc...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)TBA
LigandPNGBDBM50611425(CHEMBL5280295)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent ubiquitination in presence of ATP measured after 13 hrs by fluorescenc...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)TBA
LigandPNGBDBM50611424(CHEMBL5274960)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent ubiquitination in presence of ATP measured after 13 hrs by fluorescenc...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)TBA
LigandPNGBDBM50611423(CHEMBL5269966)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent ubiquitination in presence of ATP measured after 13 hrs by fluorescenc...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Homo sapiens)TBA
LigandPNGBDBM50611422(CHEMBL5289025)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent ubiquitination in presence of ATP measured after 13 hrs by fluorescenc...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))TBA
LigandPNGBDBM50509086(CHEMBL4539558)
Affinity DataIC50:  1.85E+4nMAssay Description:Inhibition of c-ErbB-2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetVIP peptides(Homo sapiens (Human))TBA
LigandPNGBDBM50611420(CHEMBL5285378)
Affinity DataIC50:  1.92E+4nMAssay Description:Displacement of [125I]-VIP from Vasoactive intestinal peptide (unknown origin) incubated for 120 mins by gamma scintillation counter analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetVIP peptides(Homo sapiens (Human))TBA
LigandPNGBDBM50611419(CHEBI:80954 | SCEPTRIN | Sceptrin)
Affinity DataIC50:  1.98E+4nMAssay Description:Displacement of [125I]-VIP from Vasoactive intestinal peptide (unknown origin) incubated for 120 mins by gamma scintillation counter analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))TBA
LigandPNGBDBM50509084(CHEMBL4531006)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of c-ErbB-2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50509086(CHEMBL4539558)
Affinity DataIC50:  2.96E+4nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))TBA
LigandPNGBDBM50509088(CHEMBL4575427)
Affinity DataIC50:  3.79E+4nMAssay Description:Inhibition of c-ErbB-2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails PubMed
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