Affinity DataKi: 90nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
Affinity DataKi: 320nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Binding affinity determined against ETA receptor in porcine aortic smooth muscle membraneMore data for this Ligand-Target Pair
Affinity DataKi: 620nMAssay Description:Binding affinity of the compound was determined against ETA receptor in porcine aortic smooth muscle membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Non-competitive inhibition of human alpha-glucosidase expressed in Saccharomyces cerevisiae using p-nitrophenyl-alpha-D-glucopyranoside as substrate ...More data for this Ligand-Target Pair
Affinity DataKi: 1.70E+3nMAssay Description:Binding affinity of the compound was determined against ETA receptor in porcine aortic smooth muscle membraneMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
Affinity DataKi: 2.60E+3nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+3nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
Affinity DataKi: 3.45E+3nMAssay Description:Non-competitive inhibition of human alpha-glucosidase expressed in Saccharomyces cerevisiae using p-nitrophenyl-alpha-D-glucopyranoside as substrate ...More data for this Ligand-Target Pair
Affinity DataKi: 3.50E+3nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytesMore data for this Ligand-Target Pair
Affinity DataKi: 3.80E+3nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
Affinity DataKi: 4.00E+3nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
Affinity DataKi: 4.40E+3nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytesMore data for this Ligand-Target Pair
Affinity DataKi: 4.90E+3nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
Affinity DataKi: 9.50E+3nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
Affinity DataKi: >1.80E+4nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytesMore data for this Ligand-Target Pair
Affinity DataKi: >2.20E+4nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+4nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytesMore data for this Ligand-Target Pair
Affinity DataKi: 2.40E+4nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytesMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+4nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytesMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+4nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
Affinity DataKi: 4.20E+4nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytesMore data for this Ligand-Target Pair
Affinity DataKi: 6.70E+4nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytesMore data for this Ligand-Target Pair
Affinity DataKi: 6.80E+4nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytesMore data for this Ligand-Target Pair
Affinity DataKi: 7.00E+4nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytesMore data for this Ligand-Target Pair
Affinity DataKi: 7.40E+4nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytesMore data for this Ligand-Target Pair
Affinity DataKi: 9.00E+4nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytesMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytesMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytesMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytesMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytesMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of IL-1 beta converting enzyme (ICE) in human blood monocytes expressed as KonMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: <0.5nMAssay Description:Inhibition of human PI3Kdelta (R108 to Q1044 residues) expressed in mammalian expression system incubated for 60 mins by ADAPTA assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human PI3Kdelta (R108 to Q1044 residues) expressed in mammalian expression system incubated for 60 mins by ADAPTA assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human PI3Kdelta (R108 to Q1044 residues) expressed in mammalian expression system incubated for 60 mins by ADAPTA assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human PI3Kdelta (R108 to Q1044 residues) expressed in mammalian expression system incubated for 60 mins by ADAPTA assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human PI3Kdelta (R108 to Q1044 residues) expressed in mammalian expression system incubated for 60 mins by ADAPTA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human Aurora kinase A (E122 to K401 residues) expressed in mammalian expression system by Z'LYTE assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human PI3Kgamma (S144 to A1102 residues) expressed in mammalian expression system incubated for 60 mins by ADAPTA assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human PI3Kgamma (S144 to A1102 residues) expressed in mammalian expression system incubated for 60 mins by ADAPTA assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human PI3Kdelta (R108 to Q1044 residues) expressed in mammalian expression system incubated for 60 mins by ADAPTA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human Aurora kinase B (D25 to A303 residues) expressed in mammalian expression system by Z'LYTE assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human PI3Kgamma (S144 to A1102 residues) expressed in mammalian expression system incubated for 60 mins by ADAPTA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human Aurora kinase B (D25 to A303 residues) expressed in mammalian expression system by Z'LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human Aurora kinase A (E122 to K401 residues) expressed in mammalian expression system by Z'LYTE assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human PI3Kgamma (S144 to A1102 residues) expressed in mammalian expression system incubated for 60 mins by ADAPTA assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human PI3Kgamma (S144 to A1102 residues) expressed in mammalian expression system incubated for 60 mins by ADAPTA assayMore data for this Ligand-Target Pair