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Found 161 with Last Name = 'hargreaves' and Initial = 'rj'
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Labortories

Curated by ChEMBL
LigandPNGBDBM50440788(CHEMBL2431249)
Affinity DataKi:  0.0170nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Labortories

Curated by ChEMBL
LigandPNGBDBM50440782(CHEMBL2431246)
Affinity DataKi:  0.0190nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Labortories

Curated by ChEMBL
LigandPNGBDBM50440784(CHEMBL2431253)
Affinity DataKi:  0.0210nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Labortories

Curated by ChEMBL
LigandPNGBDBM50356282(CHEMBL1910936)
Affinity DataKi:  0.0210nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Labortories

Curated by ChEMBL
LigandPNGBDBM50440791(CHEMBL2431256)
Affinity DataKi:  0.0220nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Labortories

Curated by ChEMBL
LigandPNGBDBM50440793(CHEMBL2431254)
Affinity DataKi:  0.0340nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Labortories

Curated by ChEMBL
LigandPNGBDBM50385314(CHEMBL2035981)
Affinity DataKi:  0.0400nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Labortories

Curated by ChEMBL
LigandPNGBDBM50440786(CHEMBL2431251)
Affinity DataKi:  0.0450nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Labortories

Curated by ChEMBL
LigandPNGBDBM50440789(CHEMBL2431248)
Affinity DataKi:  0.0460nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Labortories

Curated by ChEMBL
LigandPNGBDBM50440790(CHEMBL2431247)
Affinity DataKi:  0.0560nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Labortories

Curated by ChEMBL
LigandPNGBDBM50440785(CHEMBL2431252)
Affinity DataKi:  0.0940nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin(GUINEA PIG)
Merck Sharp and Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50040671(1-[5-(3-Aza-bicyclo[3.2.2]non-3-yl)-1-methyl-2-oxo...)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Labortories

Curated by ChEMBL
LigandPNGBDBM50440783(CHEMBL2429882)
Affinity DataKi:  0.110nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Labortories

Curated by ChEMBL
LigandPNGBDBM50440792(CHEMBL2431255)
Affinity DataKi:  0.110nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Labortories

Curated by ChEMBL
LigandPNGBDBM50440787(CHEMBL2431250)
Affinity DataKi:  0.5nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Labortories

Curated by ChEMBL
LigandPNGBDBM50224431(CHEMBL236593 | MK-0974 | N-[(3R,6S)-6-(2,3-difluor...)
Affinity DataKi:  0.770nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetCholecystokinin(GUINEA PIG)
Merck Sharp and Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM82514(1-[[(3R)-2,3-Dihydro-1-methyl-2-oxo-5-[(hexahydro-...)
Affinity DataKi:  1.20nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCholecystokinin(GUINEA PIG)
Merck Sharp and Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50061220(1-((S)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Affinity DataKi:  8.5nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGastrin/cholecystokinin type B receptor(RAT)
Merck Sharp and Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50040671(1-[5-(3-Aza-bicyclo[3.2.2]non-3-yl)-1-methyl-2-oxo...)
Affinity DataKi:  1.60E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGastrin/cholecystokinin type B receptor(RAT)
Merck Sharp and Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM82514(1-[[(3R)-2,3-Dihydro-1-methyl-2-oxo-5-[(hexahydro-...)
Affinity DataKi:  3.20E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50052278(5-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2...)
Affinity DataIC50:  0.0500nMAssay Description:Displacement of [125 I]-Tyr8 SP from the cloned human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218239((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...)
Affinity DataIC50:  0.0600nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218225(1-(4-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)ph...)
Affinity DataIC50:  0.0700nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218213(1-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50:  0.0700nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218240(3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50:  0.0700nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218235(1-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50:  0.0900nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220136(3-[2-{1-[3,5-di(trifluoromethyl)phenyl]ethoxy}-3-(...)
Affinity DataIC50:  0.0900nMAssay Description:Displacement of [125I]SP from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218224(1-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50:  0.0900nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218220(3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50:  0.0900nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218220(3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50:  0.0900nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106711(5-[2-[1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxy]-3...)
Affinity DataIC50:  0.0900nMAssay Description:In vitro inhibition of binding of [125I]-substance P to tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Labortories

Curated by ChEMBL
LigandPNGBDBM50440789(CHEMBL2431248)
Affinity DataIC50:  0.0970nMAssay Description:Antagonist activity at CGRP receptor (unknown origin) by cell based cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218212((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...)
Affinity DataIC50:  0.100nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218217((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...)
Affinity DataIC50:  0.110nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218227(3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50:  0.110nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218226(3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50:  0.110nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218231(4-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50:  0.120nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218230(((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)...)
Affinity DataIC50:  0.120nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218233((S)-5-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)p...)
Affinity DataIC50:  0.120nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218234(3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50:  0.130nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218222(3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50:  0.130nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50191091((S)-5-((((1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromet...)
Affinity DataIC50:  0.140nMAssay Description:Displacement of [125I]SP from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218218((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...)
Affinity DataIC50:  0.140nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218221(1-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50:  0.150nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218215(((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)...)
Affinity DataIC50:  0.160nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218232(4-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50:  0.160nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50191087((1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50:  0.160nMAssay Description:Displacement of [125I]SP from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50191092((1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50:  0.160nMAssay Description:Displacement of [125I]SP from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50191079(2-(((1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)p...)
Affinity DataIC50:  0.170nMAssay Description:Displacement of [125I]SP from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218228(3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50:  0.180nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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