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Found 481 with Last Name = 'harris' and Initial = 'ls'
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50127165(10-hydroxy-17-methoxy-4,13-dimethyl-(13R,17S)-12-o...)
Affinity DataKi:  0.0230nMAssay Description:In vitro binding affinity at opioid receptor mu 1 was determined in C6 rat glioma cells using [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  0.0400nMAssay Description:Compound was evaluated for its ability to displace [3H]p-CI-DPDPE in C6 glioma cells expressing the cloned Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50248793(17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5alpha-e...)
Affinity DataKi:  0.0430nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membrane by liquid scintillation and luminescence counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50248825((2E)-3-(2-chlorophenyl)-N-[(1S,5R,13R,14R,17S)-4-(...)
Affinity DataKi:  0.0790nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membrane by liquid scintillation and luminescence counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50127167(10-hydroxy-17-(3-phenylpropoxy)-4-tetrahydro-2-fur...)
Affinity DataKi:  0.0800nMAssay Description:In vitro binding affinity at opioid receptor kappa 1 was determined in human CHO cells using [3H]U-69593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50248826((2E)-N-[(1S,5R,13R,14R,17S)-4-(cyclopropylmethyl)-...)
Affinity DataKi:  0.0850nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membrane by liquid scintillation and luminescence counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50127167(10-hydroxy-17-(3-phenylpropoxy)-4-tetrahydro-2-fur...)
Affinity DataKi:  0.0900nMAssay Description:In vitro binding affinity at opioid receptor delta 1 was determined in C6 rat glioma cells using [3H]Ile5,6 deltorphin IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50127162(10-hydroxy-17-(3-phenylpropoxy)-4-propyl-(13R,17S)...)
Affinity DataKi:  0.0900nMAssay Description:In vitro binding affinity at opioid receptor mu 1 was determined in C6 rat glioma cells using [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50248795((2E)-N-[(1S,5R,13R,14R,17S)-4-(cyclopropylmethyl)-...)
Affinity DataKi:  0.110nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membrane by liquid scintillation and luminescence counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50127163(4-allyl-10-hydroxy-17-(3-phenylpropoxy)-(13R,17S)-...)
Affinity DataKi:  0.110nMAssay Description:In vitro binding affinity at opioid receptor kappa 1 was determined in human CHO cells using [3H]U-69593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50248828(14beta-Allyloxy-17-cyclopropylmethyl-4,5alpha-epox...)
Affinity DataKi:  0.120nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membrane by liquid scintillation and luminescence counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50133226(15-methoxy-3-methyl-19-(1-methylbutyl)-13-oxa-3-az...)
Affinity DataKi:  0.130nMAssay Description:Binding affinity against Opioid receptor kappa 1 isolated from rat brain membarane was determined using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50133224(10-hydroxy-4,13-dimethyl-17-(3-phenylpropoxy)-12-o...)
Affinity DataKi:  0.140nMAssay Description:Binding affinity against Opioid receptor delta 1 isolated from rat brain membarane was determined using [3H][Ile]-deltorphin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50133227(10,17-dimethoxy-4,13-dimethyl-12-oxa-4-azapentacyc...)
Affinity DataKi:  0.150nMAssay Description:Binding affinity against Opioid receptor mu 1 isolated from rat brain membarane was determined using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50248827((2E)-N-[(1S,5R,13R,14R,17S)-17-(benzyloxy)-4-(cycl...)
Affinity DataKi:  0.160nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membrane by liquid scintillation and luminescence counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50248793(17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5alpha-e...)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membrane by liquid scintillation and luminescence counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50367123(ETORPHINE | M99)
Affinity DataKi:  0.180nMAssay Description:Binding affinity against Opioid receptor kappa 1 isolated from rat brain membarane was determined using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50217956((1R,5S)-(+)-5-(3-hydroxyphenyl)-9-methylene-2-phen...)
Affinity DataKi:  0.190nMAssay Description:Displacement of [125I]IOXY from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50217952((1R,5R,9S)-(-)-9-hydroxy-5-(3-hydroxyphenyl-2-phen...)
Affinity DataKi:  0.190nMAssay Description:Displacement of [125I]IOXY from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50133226(15-methoxy-3-methyl-19-(1-methylbutyl)-13-oxa-3-az...)
Affinity DataKi:  0.190nMAssay Description:Binding affinity against Opioid receptor mu 1 isolated from rat brain membarane was determined using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50127163(4-allyl-10-hydroxy-17-(3-phenylpropoxy)-(13R,17S)-...)
Affinity DataKi:  0.200nMAssay Description:In vitro binding affinity at opioid receptor mu 1 was determined in C6 rat glioma cells using [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50398951(CHEMBL2179258)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]DAMGO from MOR in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50127167(10-hydroxy-17-(3-phenylpropoxy)-4-tetrahydro-2-fur...)
Affinity DataKi:  0.200nMAssay Description:In vitro binding affinity at opioid receptor mu 1 was determined in C6 rat glioma cells using [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50133224(10-hydroxy-4,13-dimethyl-17-(3-phenylpropoxy)-12-o...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity against Opioid receptor mu 1 isolated from rat brain membarane was determined using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50133226(15-methoxy-3-methyl-19-(1-methylbutyl)-13-oxa-3-az...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity against Opioid receptor delta 1 isolated from rat brain membarane was determined using [3H][Ile]-deltorphin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50248855(14beta-Acetoyloxy-17-cyclopropylmethyl-4,5alpha-ep...)
Affinity DataKi:  0.210nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membrane by liquid scintillation and luminescence counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50398952(CHEMBL2179264)
Affinity DataKi:  0.240nMAssay Description:Displacement of [3H]DAMGO from MOR in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50248828(14beta-Allyloxy-17-cyclopropylmethyl-4,5alpha-epox...)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membrane by liquid scintillation and luminescence counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50127170(4-cyclobutylmethyl-10-hydroxy-17-(3-phenylpropoxy)...)
Affinity DataKi:  0.25nMAssay Description:In vitro binding affinity at opioid receptor mu 1 was determined in C6 rat glioma cells using [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50367123(ETORPHINE | M99)
Affinity DataKi:  0.260nMAssay Description:Binding affinity against Opioid receptor mu 1 isolated from rat brain membarane was determined using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50248857((1S,5R,13R,14R,17S)-4-(cyclopropylmethyl)-10-hydro...)
Affinity DataKi:  0.260nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membrane by liquid scintillation and luminescence counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50127163(4-allyl-10-hydroxy-17-(3-phenylpropoxy)-(13R,17S)-...)
Affinity DataKi:  0.260nMAssay Description:In vitro binding affinity at opioid receptor delta 1 was determined in C6 rat glioma cells using [3H]Ile5,6 deltorphin IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50367123(ETORPHINE | M99)
Affinity DataKi:  0.270nMAssay Description:Binding affinity against Opioid receptor delta 1 isolated from rat brain membarane was determined using [3H][Ile]-deltorphin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50248825((2E)-3-(2-chlorophenyl)-N-[(1S,5R,13R,14R,17S)-4-(...)
Affinity DataKi:  0.270nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membrane by liquid scintillation and luminescence counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50248857((1S,5R,13R,14R,17S)-4-(cyclopropylmethyl)-10-hydro...)
Affinity DataKi:  0.280nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membrane by liquid scintillation and luminescence counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50248794((2E)-N-[(1S,5R,13R,14R,17S)-4-(cyclopropylmethyl)-...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membrane by liquid scintillation and luminescence counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50041240((6S,11R)-3-Allyl-6,11-dimethyl-1,2,3,4,5,6-hexahyd...)
Affinity DataKi:  0.300nMAssay Description:Ki value determined against Opioid receptor kappa 1 using [3H]U69, 593 at the Kd concentration 0.95 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50248826((2E)-N-[(1S,5R,13R,14R,17S)-4-(cyclopropylmethyl)-...)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membrane by liquid scintillation and luminescence counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50249017(14-O-phenylpropylnaltrexone | 4-cyclopropylmethyl-...)
Affinity DataKi:  0.340nMAssay Description:In vitro binding affinity at opioid receptor mu 1 was determined in C6 rat glioma cells using [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50248794((2E)-N-[(1S,5R,13R,14R,17S)-4-(cyclopropylmethyl)-...)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membrane by liquid scintillation and luminescence counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50248795((2E)-N-[(1S,5R,13R,14R,17S)-4-(cyclopropylmethyl)-...)
Affinity DataKi:  0.360nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membrane by liquid scintillation and luminescence counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50127162(10-hydroxy-17-(3-phenylpropoxy)-4-propyl-(13R,17S)...)
Affinity DataKi:  0.370nMAssay Description:In vitro binding affinity at opioid receptor kappa 1 was determined in human CHO cells using [3H]U-69593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50247803(Beta-Funeltrexamine | CHEMBL473136 | beta-funaltre...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]DAMGO from MOR in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50095694(3-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  0.400nMAssay Description:Ki value determined against Opioid receptor kappa 1 using [3H]U69, 593 at the Kd concentration 0.95 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50133224(10-hydroxy-4,13-dimethyl-17-(3-phenylpropoxy)-12-o...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity against Opioid receptor kappa 1 isolated from rat brain membarane was determined using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50095706(4-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  0.400nMAssay Description:Ki value determined against Opioid receptor kappa 1 using [3H]U69, 593 at the Kd concentration 0.95 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50249017(14-O-phenylpropylnaltrexone | 4-cyclopropylmethyl-...)
Affinity DataKi:  0.410nMAssay Description:In vitro binding affinity at opioid receptor kappa 1 was determined in human CHO cells using [3H]U-69593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50248856((1S,5R,13R,14R,17S)-4-(cyclopropylmethyl)-10-hydro...)
Affinity DataKi:  0.420nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membrane by liquid scintillation and luminescence counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50127170(4-cyclobutylmethyl-10-hydroxy-17-(3-phenylpropoxy)...)
Affinity DataKi:  0.460nMAssay Description:In vitro binding affinity at opioid receptor delta 1 was determined in C6 rat glioma cells using [3H]Ile5,6 deltorphin IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50037492(CHEMBL113995 | [(S)-2-(2-{(S)-2-[(S)-2-Amino-3-(4-...)
Affinity DataKi:  0.460nMAssay Description:Binding affinity against opioid receptor by displacing radioligand [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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