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Found 242 with Last Name = 'hashizume' and Initial = 'm'
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50116105(3-(6-(dimethylamino)-4-methylpyridin-3-yl)-2,5-dim...)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at CRF1 receptor in human IMR32 cells assessed as inhibition of CRF-induced intracellular cAMP accumulation after 30 mins by immu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50398565(CHEMBL2179195)
Affinity DataIC50:  7.10nMAssay Description:Antagonist activity at CRF1 receptor in human IMR32 cells assessed as inhibition of CRF-induced intracellular cAMP accumulation after 30 mins by immu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101691(US8530504, 53)
Affinity DataIC50:  18nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101693(US8530504, 55)
Affinity DataIC50:  19nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101692(US8530504, 54)
Affinity DataIC50:  20nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50394516(CHEMBL2160157)
Affinity DataIC50:  22nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-induced intracellular cAMP production preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50389532(CHEMBL2063375)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-stimulated intracellular cAMP accumulation after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50389532(CHEMBL2063375)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-induced intracellular cAMP production preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101697(US8530504, 59)
Affinity DataIC50:  24nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50389530(CHEMBL2063372)
Affinity DataIC50:  24nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-stimulated intracellular cAMP accumulation after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101679(US8530504, 41)
Affinity DataIC50:  25nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101686(US8530504, 48)
Affinity DataIC50:  25nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101663(US8530504, 24)
Affinity DataIC50:  26nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101684(US8530504, 46)
Affinity DataIC50:  26nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101704(US8530504, 66)
Affinity DataIC50:  26nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50394527(CHEMBL2160161)
Affinity DataIC50:  28nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-induced intracellular cAMP production preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101694(US8530504, 56)
Affinity DataIC50:  31nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101678(US8530504, 40)
Affinity DataIC50:  32nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101685(US8530504, 47)
Affinity DataIC50:  32nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50394520(CHEMBL2160170)
Affinity DataIC50:  32nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-induced intracellular cAMP production preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101665(US8530504, 26)
Affinity DataIC50:  33nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101698(US8530504, 60)
Affinity DataIC50:  33nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101723(US8530504, 86)
Affinity DataIC50:  33nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101680(US8530504, 42)
Affinity DataIC50:  35nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101689(US8530504, 51)
Affinity DataIC50:  36nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101724(US8530504, 87)
Affinity DataIC50:  36nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50394525(CHEMBL2160164)
Affinity DataIC50:  36nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-induced intracellular cAMP production preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM5108(US8530504, 76)
Affinity DataIC50:  37nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101699(US8530504, 61)
Affinity DataIC50:  39nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101643(US8530504, 2)
Affinity DataIC50:  39nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101666(US8530504, 28)
Affinity DataIC50:  40nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101664(US8530504, 25)
Affinity DataIC50:  43nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50394514(CHEMBL2160159)
Affinity DataIC50:  43nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-induced intracellular cAMP production preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50398579(CHEMBL2179182)
Affinity DataIC50:  43nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101662(US8530504, 23)
Affinity DataIC50:  44nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101667(US8530504, 29)
Affinity DataIC50:  45nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101681(US8530504, 43)
Affinity DataIC50:  45nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101727(US8530504, 93)
Affinity DataIC50:  45nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101729(US8530504, 197 | US8530504, 94 | US8530504, 96)
Affinity DataIC50:  45nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50389539(CHEMBL2063382)
Affinity DataIC50:  45nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-stimulated intracellular cAMP accumulation after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50389539(CHEMBL2063382)
Affinity DataIC50:  45nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-induced intracellular cAMP production preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50398587(CHEMBL2179197 | US8530504, 4)
Affinity DataIC50:  46nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50389540(CHEMBL2063373)
Affinity DataIC50:  46nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-stimulated intracellular cAMP accumulation after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50398566(CHEMBL2179196)
Affinity DataIC50:  46nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50398587(CHEMBL2179197 | US8530504, 4)
Affinity DataIC50:  46nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101719(US8530504, 83)
Affinity DataIC50:  47nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM4895(US850504, 92)
Affinity DataIC50:  47nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50398578(CHEMBL2179183 | US8530504, 27)
Affinity DataIC50:  48nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101683(US8530504, 45)
Affinity DataIC50:  48nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM101707(US8530504, 69)
Affinity DataIC50:  48nMAssay Description:A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.More data for this Ligand-Target Pair
In DepthDetails US Patent
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