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Found 21 with Last Name = 'ho' and Initial = 'mn'
TargetCruzipain(Trypanosoma cruzi)
Universidade De Mogi Das Cruzes (Umc)

Curated by ChEMBL
LigandPNGBDBM50331787((S)-N-((S)-1-cyano-2-(4-cyano-2-fluorophenyl)ethyl...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Cruzipain (104 to 212 residues) expressed in baculovirus expression system using Z-Phe-Arg-AMC as substra...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade De Mogi Das Cruzes (Umc)

Curated by ChEMBL
LigandPNGBDBM19518((2S)-N-(cyanomethyl)-4-methyl-2-{[(1S)-2,2,2-trifl...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Cruzipain (104 to 212 residues) expressed in baculovirus expression system using Z-Phe-Arg-AMC as substra...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277781((2S)-2-[(2S)-2-[(5-ethoxy-1,2-oxazol-3-yl)formamid...)
Affinity DataIC50:  5nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix

Curated by ChEMBL
LigandPNGBDBM50069989((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277889(CARFILZOMIB | CHEMBL451887)
Affinity DataIC50:  14nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277779(CHEMBL484003 | N-((S)-3-methoxy-1-((S)-3-methoxy-1...)
Affinity DataIC50:  21nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277815(3-methoxy-N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)...)
Affinity DataIC50:  22nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277816(3-methoxy-N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)...)
Affinity DataIC50:  36nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277780(5-ethoxy-N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)-...)
Affinity DataIC50:  41nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277818(2-Me-5-thiazole-Ser(OMe)-Ser(OMe)-Phe-ketoepoxide ...)
Affinity DataIC50:  82nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277778(CHEMBL484002 | N-((S)-3-methoxy-1-((S)-3-methoxy-1...)
Affinity DataIC50:  93nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277733((2S)-3-methoxy-2-[(2S)-3-methoxy-2-[(5-methyl-1,2-...)
Affinity DataIC50:  238nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277734(CHEMBL484157 | N-((S)-3-methoxy-1-((S)-3-methoxy-1...)
Affinity DataIC50:  607nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277817(CHEMBL483740 | N-((S)-3-methoxy-1-((S)-3-methoxy-1...)
Affinity DataIC50:  784nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Central University Of Las Villas

Curated by ChEMBL
LigandPNGBDBM50176699(CHEMBL411981 | askendoside B)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibitory activity against tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Central University Of Las Villas

Curated by ChEMBL
LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  1.67E+4nMAssay Description:Inhibitory activity against tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Central University Of Las Villas

Curated by ChEMBL
LigandPNGBDBM50176700(CHEMBL371147 | askendoside D)
Affinity DataIC50:  4.89E+4nMAssay Description:Inhibitory activity against tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Central University Of Las Villas

Curated by ChEMBL
LigandPNGBDBM50176696(CHEMBL372097 | cycloorbicoside G)
Affinity DataIC50:  5.46E+4nMAssay Description:Inhibitory activity against tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Central University Of Las Villas

Curated by ChEMBL
LigandPNGBDBM50370694(BRYOAMARIDE)
Affinity DataIC50:  8.50E+4nMAssay Description:Inhibitory activity against tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Central University Of Las Villas

Curated by ChEMBL
LigandPNGBDBM50176701(CHEMBL378140 | cyclosieversioside)
Affinity DataIC50:  9.23E+4nMAssay Description:Inhibitory activity against tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Central University Of Las Villas

Curated by ChEMBL
LigandPNGBDBM50176698(CHEMBL201643 | cyclocarposide)
Affinity DataIC50:  1.02E+5nMAssay Description:Inhibitory activity against tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed