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Found 740 with Last Name = 'holzgrabe' and Initial = 'u'
TargetKappa-type opioid receptor(Homo sapiens (Human))
Temple University

Curated by PDSP Ki Database
LigandPNGBDBM86549(CAS_213055 | NSC_213055 | TRK-820)
Affinity DataKi:  0.0250nMMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Temple University

Curated by PDSP Ki Database
LigandPNGBDBM86549(CAS_213055 | NSC_213055 | TRK-820)
Affinity DataKi:  0.0750nMMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50241132(3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9...)
Affinity DataKi:  0.331nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 Y177Q/T423H mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50241132(3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9...)
Affinity DataKi:  0.427nMAssay Description:Displacement of [3H]-NMS from wild-type human muscarinic M2 receptor expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50241132(3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9...)
Affinity DataKi:  0.437nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 W422A mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50241132(3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9...)
Affinity DataKi:  0.724nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 Y177Q mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50241132(3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-NMS from wild-type human muscarinic M5 receptor expressed in CHO-K1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50452855(Isoptpo Hyoscine | Scopolamine)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-NMS from wild-type human muscarinic M5 receptor expressed in CHO-K1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497843(CHEMBL1197177)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]-NMS from wild-type human muscarinic M2 receptor expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50448377(CHEMBL3121473)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 Y177Q/T423H mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Temple University

Curated by PDSP Ki Database
LigandPNGBDBM86547(CAS_135349 | NSC_135349 | U50,488H)
Affinity DataKi:  2.20nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50448377(CHEMBL3121473)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]-NMS from wild-type human muscarinic M2 receptor expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497842(CHEMBL3323281)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]-NMS from wild-type human muscarinic M2 receptor expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497842(CHEMBL3323281)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 Y177Q/T423H mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497835(ENDO-ATROPINE)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 W422A mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50452855(Isoptpo Hyoscine | Scopolamine)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-NMS from wild-type human muscarinic M2 receptor expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497835(ENDO-ATROPINE)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-NMS from wild-type human muscarinic M5 receptor expressed in CHO-K1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Temple University

Curated by PDSP Ki Database
LigandPNGBDBM86549(CAS_213055 | NSC_213055 | TRK-820)
Affinity DataKi:  3.20nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50452855(Isoptpo Hyoscine | Scopolamine)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 Y177Q mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50452855(Isoptpo Hyoscine | Scopolamine)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 W422A mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497834(CHEMBL3323284)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 Y177Q/T423H mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Temple University

Curated by PDSP Ki Database
LigandPNGBDBM86546(CAS_88373-73-3 | DPDPE | NSC_104787)
Affinity DataKi:  3.40nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50452855(Isoptpo Hyoscine | Scopolamine)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 Y177Q/T423H mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497835(ENDO-ATROPINE)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 Y177Q mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497835(ENDO-ATROPINE)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 Y177Q/T423H mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Temple University

Curated by PDSP Ki Database
LigandPNGBDBM86548(CAS_83729-01-5 | NSC_128563 | Salvinorin A)
Affinity DataKi:  4.60nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycine receptor subunit alpha-1(Homo sapiens (Human))
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50225707(CHEBI:28973 | Strychnine)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]strychnine from human glycine receptor subunit alpha-1 expressed in HEK293 cell membranes preincubated for 30 mins followed by [3...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497835(ENDO-ATROPINE)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]-NMS from wild-type human muscarinic M2 receptor expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Temple University

Curated by PDSP Ki Database
LigandPNGBDBM86549(CAS_213055 | NSC_213055 | TRK-820)
Affinity DataKi:  5.20nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497841(CHEMBL3323280)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]-NMS from wild-type human muscarinic M2 receptor expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497841(CHEMBL3323280)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 Y177Q/T423H mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497834(CHEMBL3323284)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]-NMS from wild-type human muscarinic M5 receptor expressed in CHO-K1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497834(CHEMBL3323284)
Affinity DataKi:  6.20nMAssay Description:Displacement of [3H]-NMS from wild-type human muscarinic M2 receptor expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497834(CHEMBL3323284)
Affinity DataKi:  6.5nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 W422A mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497837(CHEMBL3323283)
Affinity DataKi:  6.90nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 W422A mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497837(CHEMBL3323283)
Affinity DataKi:  7.10nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 Y177Q mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497837(CHEMBL3323283)
Affinity DataKi:  7.10nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 Y177Q/T423H mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Temple University

Curated by PDSP Ki Database
LigandPNGBDBM86548(CAS_83729-01-5 | NSC_128563 | Salvinorin A)
Affinity DataKi:  7.90nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497837(CHEMBL3323283)
Affinity DataKi:  8.10nMAssay Description:Displacement of [3H]-NMS from wild-type human muscarinic M2 receptor expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497842(CHEMBL3323281)
Affinity DataKi:  8.5nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 Y177Q mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50448377(CHEMBL3121473)
Affinity DataKi:  8.70nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 Y177Q mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Temple University

Curated by PDSP Ki Database
LigandPNGBDBM86253(CAS_100929-53-1 | DAMGO | NSC_104742 | US10836728,...)
Affinity DataKi:  8.90nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497834(CHEMBL3323284)
Affinity DataKi:  8.90nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 Y177Q mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataKi:  9.80nMAssay Description:Inhibition of human CYP2D6 by Lineweaver-Burk plotMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497841(CHEMBL3323280)
Affinity DataKi:  9.80nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 Y177Q mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497841(CHEMBL3323280)
Affinity DataKi:  9.80nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 Y104A mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50067004((S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-...)
Affinity DataKi:  10nMAssay Description:Inhibition of recombinant human FKBP12 expressed in Escherichia coli using succinyl-Ala-Phe-Pro-Phe-4-nitroanilide as substrateMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50241132(3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 Y104A mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50448377(CHEMBL3121473)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 W422A mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50067004((S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-...)
Affinity DataKi:  10nMAssay Description:Inhibition of FKBP12More data for this Ligand-Target Pair
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