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Found 505 with Last Name = 'hong' and Initial = 'sp'
TargetMelanin-concentrating hormone receptor 1(RAT)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353455(CHEMBL1830049)
Affinity DataKi:  2.40nMAssay Description:Displacement of [125I]-S36057 from rat MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(RAT)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353456(CHEMBL1830050)
Affinity DataKi:  2.5nMAssay Description:Displacement of [125I]-S36057 from rat MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(RAT)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353453(CHEMBL1830047)
Affinity DataKi:  4.30nMAssay Description:Displacement of [125I]-S36057 from rat MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(RAT)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353458(CHEMBL1830052)
Affinity DataKi:  4.90nMAssay Description:Displacement of [125I]-S36057 from rat MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(RAT)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353457(CHEMBL1830051)
Affinity DataKi:  4.90nMAssay Description:Displacement of [125I]-S36057 from rat MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(RAT)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353452(CHEMBL1830046)
Affinity DataKi:  5.20nMAssay Description:Displacement of [125I]-S36057 from rat MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(RAT)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353459(CHEMBL1830053)
Affinity DataKi:  6.5nMAssay Description:Displacement of [125I]-S36057 from rat MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(RAT)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353449(CHEMBL1830043)
Affinity DataKi:  6.70nMAssay Description:Displacement of [125I]-S36057 from rat MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(RAT)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353450(CHEMBL1830044)
Affinity DataKi:  7.80nMAssay Description:Displacement of [125I]-S36057 from rat MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(RAT)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353454(CHEMBL1830048)
Affinity DataKi:  9nMAssay Description:Displacement of [125I]-S36057 from rat MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(RAT)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353451(CHEMBL1830045)
Affinity DataKi:  11nMAssay Description:Displacement of [125I]-S36057 from rat MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(RAT)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353448(CHEMBL1830042)
Affinity DataKi:  11nMAssay Description:Displacement of [125I]-S36057 from rat MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50390028(CHEMBL2069398)
Affinity DataKi:  230nMAssay Description:Displacement of [3H]NAM from mGluR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50390029(CHEMBL2069397)
Affinity DataKi:  410nMAssay Description:Displacement of [3H]NAM from mGluR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50390029(CHEMBL2069397)
Affinity DataKi:  410nMAssay Description:Displacement of [3H]NAM from mGluR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112149(CHEMBL3609877)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112154(CHEMBL3608403)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112151(CHEMBL3608400)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112152(CHEMBL3608401 | US9464044, 84)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112133(CHEMBL3609861 | US9464044, 71)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112143(CHEMBL3609871 | US9464044, 73)
Affinity DataIC50:  1nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112127(CHEMBL3608407 | US9464044, 76)
Affinity DataIC50:  2nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112145(CHEMBL3609873)
Affinity DataIC50:  2nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112142(CHEMBL3609870 | US9464044, 81)
Affinity DataIC50:  2nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Incheon University Industry Academic Cooperation Foundation

US Patent
LigandPNGBDBM473585(US10844062, Example 21)
Affinity DataIC50:  4.10nMAssay Description:The inhibitory activities of the compounds of the present invention against VEGFR-2 tyrosine kinase were analyzed using ADP-Glo™ kinase assay kit com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112141(CHEMBL3609869 | US9464044, 3)
Affinity DataIC50:  6nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112154(CHEMBL3608403)
Affinity DataIC50:  8nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112140(CHEMBL3609868 | US9464044, 68)
Affinity DataIC50:  9nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Incheon University Industry Academic Cooperation Foundation

US Patent
LigandPNGBDBM473613(US10844062, Example 49)
Affinity DataIC50:  10nMAssay Description:The inhibitory activities of the compounds of the present invention against VEGFR-2 tyrosine kinase were analyzed using ADP-Glo™ kinase assay kit com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112149(CHEMBL3609877)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112153(CHEMBL3608402 | US9464044, 83)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112133(CHEMBL3609861 | US9464044, 71)
Affinity DataIC50: >10nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Incheon University Industry Academic Cooperation Foundation

US Patent
LigandPNGBDBM473190(US10844062, Example 1)
Affinity DataIC50:  11nMAssay Description:The inhibitory activities of the compounds of the present invention against VEGFR-2 tyrosine kinase were analyzed using ADP-Glo™ kinase assay kit com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Incheon University Industry Academic Cooperation Foundation

US Patent
LigandPNGBDBM473594(US10844062, Example 30)
Affinity DataIC50:  11nMAssay Description:The inhibitory activities of the compounds of the present invention against VEGFR-2 tyrosine kinase were analyzed using ADP-Glo™ kinase assay kit com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Incheon University Industry Academic Cooperation Foundation

US Patent
LigandPNGBDBM473640(US10844062, Example 76)
Affinity DataIC50:  11nMAssay Description:The inhibitory activities of the compounds of the present invention against VEGFR-2 tyrosine kinase were analyzed using ADP-Glo™ kinase assay kit com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112143(CHEMBL3609871 | US9464044, 73)
Affinity DataIC50:  12nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112152(CHEMBL3608401 | US9464044, 84)
Affinity DataIC50:  12nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Incheon University Industry Academic Cooperation Foundation

US Patent
LigandPNGBDBM473593(US10844062, Example 29)
Affinity DataIC50:  12nMAssay Description:The inhibitory activities of the compounds of the present invention against VEGFR-2 tyrosine kinase were analyzed using ADP-Glo™ kinase assay kit com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Incheon University Industry Academic Cooperation Foundation

US Patent
LigandPNGBDBM473573(US10844062, Example 9)
Affinity DataIC50:  12nMAssay Description:The inhibitory activities of the compounds of the present invention against VEGFR-2 tyrosine kinase were analyzed using ADP-Glo™ kinase assay kit com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Incheon University Industry Academic Cooperation Foundation

US Patent
LigandPNGBDBM473600(US10844062, Example 36)
Affinity DataIC50:  12nMAssay Description:The inhibitory activities of the compounds of the present invention against VEGFR-2 tyrosine kinase were analyzed using ADP-Glo™ kinase assay kit com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112148(CHEMBL3609876)
Affinity DataIC50:  13nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112141(CHEMBL3609869 | US9464044, 3)
Affinity DataIC50:  13nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Incheon University Industry Academic Cooperation Foundation

US Patent
LigandPNGBDBM473587(US10844062, Example 23)
Affinity DataIC50:  14nMAssay Description:The inhibitory activities of the compounds of the present invention against VEGFR-2 tyrosine kinase were analyzed using ADP-Glo™ kinase assay kit com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112150(CHEMBL3608399)
Affinity DataIC50:  14nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112131(CHEMBL3608411 | US9464044, 80)
Affinity DataIC50:  15nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112153(CHEMBL3608402 | US9464044, 83)
Affinity DataIC50:  18nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Incheon University Industry Academic Cooperation Foundation

US Patent
LigandPNGBDBM473629(US10844062, Example 65)
Affinity DataIC50:  21nMAssay Description:The inhibitory activities of the compounds of the present invention against VEGFR-2 tyrosine kinase were analyzed using ADP-Glo™ kinase assay kit com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112127(CHEMBL3608407 | US9464044, 76)
Affinity DataIC50:  21nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Incheon University Industry Academic Cooperation Foundation

US Patent
LigandPNGBDBM473648(US10844062, Example 84)
Affinity DataIC50:  21nMAssay Description:The inhibitory activities of the compounds of the present invention against VEGFR-2 tyrosine kinase were analyzed using ADP-Glo™ kinase assay kit com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112136(CHEMBL3609864 | US9464044, 39)
Affinity DataIC50:  25nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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