TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 0.0270nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cells after 2 hrs by gamma scintillation counter analysisMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 0.0660nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cells after 2 hrs by gamma scintillation counter analysisMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 0.0810nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cells after 2 hrs by gamma scintillation counter analysisMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 0.670nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cells after 2 hrs by gamma scintillation counter analysisMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 4.30nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cells after 2 hrs by gamma scintillation counter analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Compound was tested for in vitro inhibitory activity against Candida albicans 2005E microsomal SQSMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Compound was tested for in vitro inhibitory activity against Candida albicans 2005E microsomal SQSMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Compound was tested for in vitro inhibitory activity against Candida albicans 2005E microsomal SQSMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Compound was tested for in vitro inhibitory activity against Candida albicans 2005E microsomal SQSMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Compound was tested for in vitro inhibitory activity against Candida albicans 2005E microsomal SQSMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 143nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Compound was tested for in vitro inhibitory activity against Candida albicans 2005E microsomal SQSMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Compound was tested for in vitro inhibitory activity against Candida albicans 2005E microsomal SQSMore data for this Ligand-Target Pair
Affinity DataIC50: 208nMAssay Description:Compound was tested for in vitro inhibitory activity against Candida albicans 2005E microsomal SQSMore data for this Ligand-Target Pair
Affinity DataIC50: 252nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 415nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human recombinant CYP3A4 using 7-benzyloxy-4-trifluoromethylcoumarin as substrate after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human recombinant CYP3A4 using benzoylresorufin as substrate after 45 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of human recombinant MMP-IMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+4nMAssay Description:Compound was tested for its ability to displace [3H]-senktide binding to human Tachykinin receptor 3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataEC50: 0.140nMAssay Description:Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of CGRP-stimulated cAMP production preincubated for 15 mins prior ...More data for this Ligand-Target Pair