TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 0.0300nMAssay Description:Steady state and transient kinetics to a freely reversible, non-covalently bound, human recombinant Phospholipase A2 (rhLp-PLA2) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nM ΔG°: -57.1kJ/molepH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
Affinity DataKi: 0.110nM ΔG°: -56.3kJ/molepH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 0.110nMAssay Description:Inhibitory activity against recombinant human Lp-PLA2More data for this Ligand-Target Pair
Affinity DataKi: 0.190nM ΔG°: -54.9kJ/molepH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
Affinity DataKi: 0.407nMAssay Description:Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.More data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Binding affinity for human cloned 5-hydroxytryptamine 7 receptor in HEK 293 using [3H]5-CT as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.562nMAssay Description:Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.More data for this Ligand-Target Pair
Affinity DataKi: 0.676nMAssay Description:Binding affinity for human cloned 5-hydroxytryptamine 7 receptor in HEK 293 using [3H]5-CT as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.708nMAssay Description:Binding affinity for human cloned 5-hydroxytryptamine 7 receptor in HEK 293 using [3H]5-CT as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Binding affinity for human cloned 5-hydroxytryptamine 7 receptor in HEK 293 using [3H]5-CT as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.832nMAssay Description:Binding affinity for human cloned 5-hydroxytryptamine 7 receptor in HEK 293 using [3H]5-CT as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.950nM ΔG°: -51.0kJ/molepH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Binding affinity towards Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Binding affinity for human cloned 5-hydroxytryptamine 7 receptor in HEK 293 using [3H]5-CT as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Binding affinity at human cloned 5-hydroxytryptamine 2A receptor.More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Binding affinity for human cloned 5-hydroxytryptamine 7 receptor in HEK 293 using [3H]5-CT as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Compound was tested for its binding affinity in 5-hydroxytryptamine 7 receptor (using human cloned receptors in HEK 293 and [3H]5-CT as a radioligand...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.More data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.More data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Binding affinity for human cloned 5-hydroxytryptamine 7 receptor in HEK 293 using [3H]5-CT as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.More data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.More data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Binding affinity for 5-hydroxytryptamine 1F receptor was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.More data for this Ligand-Target Pair
Affinity DataKi: 5nM ΔG°: -46.7kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
Affinity DataKi: 5nM ΔG°: -46.7kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Binding affinity for 5-hydroxytryptamine 1E receptor was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Binding affinity for human cloned 5-hydroxytryptamine 7 receptor in HEK 293 using [3H]5-CT as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Binding affinity for human cloned 5-hydroxytryptamine 7 receptor in HEK 293 using [3H]5-CT as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Binding affinity for human cloned 5-hydroxytryptamine 7 receptor in HEK 293 using [3H]5-CT as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 6.90nMAssay Description:Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.More data for this Ligand-Target Pair
Affinity DataKi: 6.90nMAssay Description:Binding affinity at human cloned 5-hydroxytryptamine 2A receptor.More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Inhibition of cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Binding affinity for Dopamine receptor D3 was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 9.10nMAssay Description:Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.More data for this Ligand-Target Pair
Affinity DataKi: 9.30nMAssay Description:Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibitory activity against human cysteine protease, cathepsin K.More data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Binding affinity for 5-hydroxytryptamine 1B receptor was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibitory activity against human cysteine protease, cathepsin K.More data for this Ligand-Target Pair