Affinity DataKi: 0.270nM ΔG°: -54.6kJ/moleT: 2°CAssay Description:The experiment was carried out according to the method of Yabuuchi et al. [Yabuuchi K. et al., Biogenic Amines, 18, 319-328 (2004)]. 50 ul of [3H] 8-...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 0.270nM ΔG°: -54.6kJ/moleT: 2°CAssay Description:[3H] citalopram binding was assayed according to the method of Owens et al. [Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997)]. Specif...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 0.410nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 0.670nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 0.880nM ΔG°: -51.7kJ/moleT: 2°CAssay Description:[3H] citalopram binding was assayed according to the method of Owens et al. [Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997)]. Specif...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 1nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nM ΔG°: -51.1kJ/moleT: 2°CAssay Description:The experiment was carried out according to the method of Yabuuchi et al. [Yabuuchi K. et al., Biogenic Amines, 18, 319-328 (2004)]. 50 ul of [3H] 8-...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 1.30nM ΔG°: -50.7kJ/moleT: 2°CAssay Description:[3H] citalopram binding was assayed according to the method of Owens et al. [Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997)]. Specif...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nM ΔG°: -50.7kJ/moleT: 2°CAssay Description:The experiment was carried out according to the method of Yabuuchi et al. [Yabuuchi K. et al., Biogenic Amines, 18, 319-328 (2004)]. 50 ul of [3H] 8-...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 1.70nM ΔG°: -50.1kJ/moleT: 2°CAssay Description:[3H] citalopram binding was assayed according to the method of Owens et al. [Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997)]. Specif...More data for this Ligand-Target Pair
Affinity DataKi: 2nM ΔG°: -49.7kJ/moleT: 2°CAssay Description:The experiment was carried out according to the method of Yabuuchi et al. [Yabuuchi K. et al., Biogenic Amines, 18, 319-328 (2004)]. 50 ul of [3H] 8-...More data for this Ligand-Target Pair
Affinity DataKi: 2.10nM ΔG°: -49.5kJ/moleT: 2°CAssay Description:The experiment was carried out according to the method of Yabuuchi et al. [Yabuuchi K. et al., Biogenic Amines, 18, 319-328 (2004)]. 50 ul of [3H] 8-...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 2.20nM ΔG°: -49.4kJ/moleT: 2°CAssay Description:[3H] citalopram binding was assayed according to the method of Owens et al. [Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997)]. Specif...More data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 2.40nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nM ΔG°: -49.1kJ/moleT: 2°CAssay Description:The experiment was carried out according to the method of Yabuuchi et al. [Yabuuchi K. et al., Biogenic Amines, 18, 319-328 (2004)]. 50 ul of [3H] 8-...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 2.70nM ΔG°: -48.9kJ/moleT: 2°CAssay Description:[3H] citalopram binding was assayed according to the method of Owens et al. [Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997)]. Specif...More data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 3.40nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 3.5nM ΔG°: -48.3kJ/moleT: 2°CAssay Description:[3H] citalopram binding was assayed according to the method of Owens et al. [Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997)]. Specif...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 4.60nM ΔG°: -47.6kJ/moleT: 2°CAssay Description:[3H] citalopram binding was assayed according to the method of Owens et al. [Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997)]. Specif...More data for this Ligand-Target Pair
Affinity DataKi: 5.10nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 5.30nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 5.30nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 5.40nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nM ΔG°: -47.1kJ/moleT: 2°CAssay Description:The experiment was carried out according to the method of Yabuuchi et al. [Yabuuchi K. et al., Biogenic Amines, 18, 319-328 (2004)]. 50 ul of [3H] 8-...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 5.5nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 6.30nM ΔG°: -46.8kJ/moleT: 2°CAssay Description:[3H] citalopram binding was assayed according to the method of Owens et al. [Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997)]. Specif...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 6.5nM ΔG°: -46.7kJ/moleT: 2°CAssay Description:[3H] citalopram binding was assayed according to the method of Owens et al. [Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997)]. Specif...More data for this Ligand-Target Pair
Affinity DataKi: 7.40nM ΔG°: -46.4kJ/moleT: 2°CAssay Description:The experiment was carried out according to the method of Yabuuchi et al. [Yabuuchi K. et al., Biogenic Amines, 18, 319-328 (2004)]. 50 ul of [3H] 8-...More data for this Ligand-Target Pair
Affinity DataKi: 7.70nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 8.20nM ΔG°: -46.2kJ/moleT: 2°CAssay Description:[3H] citalopram binding was assayed according to the method of Owens et al. [Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997)]. Specif...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 8.40nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 8.5nM ΔG°: -46.1kJ/moleT: 2°CAssay Description:The experiment was carried out according to the method of Yabuuchi et al. [Yabuuchi K. et al., Biogenic Amines, 18, 319-328 (2004)]. 50 ul of [3H] 8-...More data for this Ligand-Target Pair
Affinity DataKi: 8.80nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 9.40nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 9.90nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 11nM ΔG°: -45.4kJ/moleT: 2°CAssay Description:[3H] citalopram binding was assayed according to the method of Owens et al. [Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997)]. Specif...More data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 12nM ΔG°: -45.2kJ/moleT: 2°CAssay Description:The experiment was carried out according to the method of Yabuuchi et al. [Yabuuchi K. et al., Biogenic Amines, 18, 319-328 (2004)]. 50 ul of [3H] 8-...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 14nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 17nM ΔG°: -44.3kJ/moleT: 2°CAssay Description:The experiment was carried out according to the method of Yabuuchi et al. [Yabuuchi K. et al., Biogenic Amines, 18, 319-328 (2004)]. 50 ul of [3H] 8-...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Dainippon Sumitomo Pharma
US Patent
Dainippon Sumitomo Pharma
US Patent
Affinity DataKi: 18nM ΔG°: -44.2kJ/moleT: 2°CAssay Description:[3H] citalopram binding was assayed according to the method of Owens et al. [Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997)]. Specif...More data for this Ligand-Target Pair