Affinity DataKi: 0.900nMAssay Description:Inhibition of PARP2 (unknown origin) after 1 min in presence of NAD by top count analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of Mycobacterium tuberculosis dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of PARP1 (unknown origin) after 1 min in presence of NAD by top count analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition of human recombinant full-length PARP1 after 4 mins by [32P]NAD+ incorporation assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
R. C. Patel Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
R. C. Patel Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Inhibition of Escherichia coli H560 DNA gyrase B ATPase activity after 30 mins by ammonium molybdate/malachite green-based phosphate detection assayMore data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Inhibition of human recombinant MMP9More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of human recombinant MMP2More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Affinity DataKi: 33nMAssay Description:Inhibition of human recombinant MMP1More data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Inhibition of human recombinant MMP3More data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Affinity DataIC50: 0.00400nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.00700nMAssay Description:Inhibition of MMP3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.00800nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.0380nMAssay Description:Inhibition of MMP3 (unknown origin)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Affinity DataIC50: 0.0410nMAssay Description:Inhibition of MMP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.0620nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Affinity DataIC50: 0.0760nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Inhibition of recombinant human PARP2 using histone as substrate after 1 hr in presence of NAD+ by ELISAMore data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.570nMAssay Description:Inhibition of PARP1 (unknown origin) after 1 min in presence of NAD by top count analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.650nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human recombinant MMP2 using (7-amino-4-methyl-coumarin)-Pro-Leu-Gly-Leu-(dinitrophenylamine)-Ala-Arg- NH2 as substrate by fluorimetric...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of mouse recombinant PARP2 by chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.740nMAssay Description:Inhibition of PARP1 (unknown origin) by NAD+ based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Affinity DataIC50: 0.930nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PARP1 (unknown origin) using histone as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant human PARP1 using histone as substrate after 1 hr in presence of NAD+ by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of PARP2 (unknown origin) by biotinylated NAD+-based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Aurora A (unknown origin) using kemptide acetate as substrate measured after 30 mins by kinase-glo luminescence assayMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant human PARP1 using histone as substrate after 1 hr in presence of NAD+ by ELISAMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Indian Institute Of Technology (Bhu)
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human recombinant full-length PARP1 after 4 mins by [32P]NAD+ incorporation assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human recombinant PARP1 by chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of PARP2 (unknown origin) using histone as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair