Found 116 with Last Name = 'jan' and Initial = 'jt' TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Taiwan University
National Taiwan University
Affinity DataKi: 520nM ΔG°: -35.9kJ/mole IC50: 1.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Taiwan University
National Taiwan University
Affinity DataKi: 2.48E+3nM ΔG°: -32.0kJ/mole IC50: 5.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Taiwan University
National Taiwan University
Affinity DataKi: 3.05E+3nM ΔG°: -31.5kJ/mole IC50: 7.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Taiwan University
National Taiwan University
Affinity DataKi: 6.44E+3nM ΔG°: -29.6kJ/mole IC50: 1.00E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Taiwan University
National Taiwan University
Affinity DataKi: 9.05E+3nM ΔG°: -28.8kJ/mole IC50: 1.00E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of Influenza A virus (A/reassortant/NIBRG-14(Viet Nam/1194/2004 x Puerto Rico/8/1934)(H5N1)) neuraminidase in virus-infected allantoic flu...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of wild type Influenza A virus A/WSN/1933(H1N1) neuraminidase in virus-infected allantoic fluid using 2'-(4-methylumbelliferyl)-alpha-D-N-...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of Influenza A virus (A/Vietnam/1194/2004 (H5N1)) recombinant neuraminidase expressed in HEK293 cells pre-incubated for 10 mins before 4-M...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Udorn/307/1972 H3N2))
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 0.350nMAssay Description:Inhibition of Influenza A virus A/Udorn/1972(H3N2) neuraminidase in virus-infected allantoic fluid using 2'-(4-methylumbelliferyl)-alpha-D-N-acetylne...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Influenza A virus (A/WSN/1933(H1N1)) recombinant neuraminidase expressed in HEK293 cells pre-incubated for 10 mins before 4-MUNANA subs...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 0.440nMAssay Description:Inhibition of Influenza A virus (A/WSN/1933(H1N1)) neuraminidase pre-incubated for 10 mins before 4-MUNANA substrate addition by fluorometryMore data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 0.480nMAssay Description:Inhibition of Influenza A virus (A/WSN/1933(H1N1)) neuraminidase pre-incubated for 10 mins before 4-MUNANA substrate addition by fluorometryMore data for this Ligand-Target Pair
Affinity DataIC50: 0.520nMAssay Description:Inhibition of Influenza A virus (A/reassortant/NIBRG-14(Viet Nam/1194/2004 x Puerto Rico/8/1934)(H5N1)) neuraminidase in virus-infected allantoic flu...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 0.640nMAssay Description:Inhibition of Influenza A virus (A/WSN/1933(H1N1)) neuraminidase pre-incubated for 10 mins before 4-MUNANA substrate addition by fluorometryMore data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 0.670nMAssay Description:Inhibition of Influenza A virus (A/WSN/1933(H1N1)) neuraminidase pre-incubated for 10 mins before 4-MUNANA substrate addition by fluorometryMore data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of Influenza A virus A/WSN/1933(H1N1)) neuraminidase in the presence of 2'-(4-methyl-umbelliferyl)-alphaD-N-acetylneuraminic acid substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 0.730nMAssay Description:Inhibition of Influenza A virus (A/reassortant/NIBRG-14(Viet Nam/1194/2004 x Puerto Rico/8/1934)(H5N1)) neuraminidase in virus-infected allantoic flu...More data for this Ligand-Target Pair
3D Structure (crystal)TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of Influenza A virus (A/WSN/1933(H1N1)) recombinant neuraminidase expressed in HEK293 cells pre-incubated for 10 mins before 4-MUNANA subs...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 0.940nMAssay Description:Inhibition of Influenza A virus (A/WSN/1933(H1N1)) neuraminidase pre-incubated for 10 mins before 4-MUNANA substrate addition by fluorometryMore data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 0.990nMAssay Description:Inhibition of Influenza A virus (A/WSN/1933(H1N1)) neuraminidase pre-incubated for 10 mins before 4-MUNANA substrate addition by fluorometryMore data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of Influenza A virus (A/WSN/1933(H1N1)) wild type neuraminidase using MUNANA as substrate preincubated for 10 mins followed by substrate a...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of Influenza A virus (A/WSN/1933(H1N1)) wild type neuraminidase using MUNANA as substrate preincubated for 10 mins followed by substrate a...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of Influenza A virus (A/WSN/1933(H1N1)) wild type neuraminidase using MUNANA as substrate preincubated for 10 mins followed by substrate a...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Influenza A virus (A/WSN/1933(H1N1)) neuraminidase pre-incubated for 10 mins before 4-MUNANA substrate addition by fluorometryMore data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of wild type Influenza A virus A/WSN/1933(H1N1) neuraminidase in virus-infected allantoic fluid using 2'-(4-methylumbelliferyl)-alpha-D-N-...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Udorn/307/1972 H3N2))
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Influenza A virus A/Udorn/1972(H3N2) neuraminidase in virus-infected allantoic fluid using 2'-(4-methylumbelliferyl)-alpha-D-N-acetylne...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of neuraminidase in wild type Influenza A virus (A/WSN/1933(H1N1)) infected in allantoic fluid of embryonated chicken egg using MUNANA as ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of neuraminidase in wild type Influenza A virus (A/WSN/1933(H1N1)) infected in allantoic fluid of embryonated chicken egg using MUNANA as ...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of Influenza A virus (A/WSN/1933(H1N1)) recombinant neuraminidase expressed in HEK293 cells pre-incubated for 10 mins before 4-MUNANA subs...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of Influenza A virus (A/Brisbane/10/2007(H3N2)) recombinant neuraminidase expressed in HEK293 cells pre-incubated for 10 mins before 4-MUN...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of Influenza A virus (A/WSN/1933(H1N1)) neuraminidase H275Y mutant using MUNANA as substrate preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of Influenza A virus (A/WSN/1933(H1N1)) neuraminidase H275Y mutant using MUNANA as substrate preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of neuraminidase in wild type Influenza A virus (A/WSN/1933(H1N1)) infected in allantoic fluid of embryonated chicken egg using MUNANA as ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of Influenza A virus (A/reassortant/NIBRG-14(Viet Nam/1194/2004 x Puerto Rico/8/1934)(H5N1)) neuraminidase in virus-infected allantoic flu...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of wild type Influenza A virus A/WSN/1933(H1N1) neuraminidase in virus-infected allantoic fluid using 2'-(4-methylumbelliferyl)-alpha-D-N-...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of Influenza A virus A/WSN/1933(H1N1)) neuraminidase in the presence of 2'-(4-methyl-umbelliferyl)-alphaD-N-acetylneuraminic acid substrat...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of wild type Influenza A virus A/WSN/1933(H1N1) neuraminidase in virus-infected allantoic fluid using 2'-(4-methylumbelliferyl)-alpha-D-N-...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Influenza A virus A/WSN/1933(H1N1)) neuraminidase in the presence of 2'-(4-methyl-umbelliferyl)-alphaD-N-acetylneuraminic acid substrat...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Influenza A virus A/WSN/1933(H1N1)) neuraminidase in the presence of 2'-(4-methyl-umbelliferyl)-alphaD-N-acetylneuraminic acid substrat...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Udorn/307/1972 H3N2))
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Influenza A virus A/Udorn/1972(H3N2) neuraminidase in virus-infected allantoic fluid using 2'-(4-methylumbelliferyl)-alpha-D-N-acetylne...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of wild type Influenza A virus A/WSN/1933(H1N1) neuraminidase in virus-infected allantoic fluid using 2'-(4-methylumbelliferyl)-alpha-D-N-...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of wild type Influenza A virus A/WSN/1933(H1N1) neuraminidase in virus-infected allantoic fluid using 2'-(4-methylumbelliferyl)-alpha-D-N-...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of Influenza A virus A/WSN/1933(H1N1)) neuraminidase in the presence of 2'-(4-methyl-umbelliferyl)-alphaD-N-acetylneuraminic acid substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of neuraminidase in wild type Influenza A virus (A/WSN/1933(H1N1)) infected in allantoic fluid of embryonated chicken egg using MUNANA as ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibition of Influenza A virus (A/Vietnam/1194/2004 (H5N1)) recombinant neuraminidase expressed in HEK293 cells pre-incubated for 10 mins before 4-M...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibition of Influenza A virus (A/WSN/1933(H1N1)) recombinant neuraminidase H275Y mutant expressed in HEK293 cells pre-incubated for 10 mins before ...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (strain A/Udorn/307/1972 H3N2))
The Genomics Research Center
Curated by ChEMBL
The Genomics Research Center
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibition of Influenza A virus A/Udorn/1972(H3N2) neuraminidase in virus-infected allantoic fluid using 2'-(4-methylumbelliferyl)-alpha-D-N-acetylne...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of Influenza A virus (A/Vietnam/1194/2004 (H5N1)) recombinant neuraminidase expressed in HEK293 cells pre-incubated for 10 mins before 4-M...More data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Inhibition of neuraminidase in wild type Influenza A virus (A/WSN/1933(H1N1)) infected in allantoic fluid of embryonated chicken egg using MUNANA as ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of Influenza A virus (A/reassortant/NIBRG-14(Viet Nam/1194/2004 x Puerto Rico/8/1934)(H5N1)) neuraminidase in virus-infected allantoic flu...More data for this Ligand-Target Pair
