TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataKi: 0.0130nMAssay Description:Displacement of [3H]citalopram from rat cortical serotonin transporter (SERT)More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataKi: 0.0300nMAssay Description:Displacement of [3H]citalopram from rat cortical serotonin transporter (SERT)More data for this Ligand-Target Pair
Affinity DataKi: 0.0850nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO cell membranes incubated for 120 mins by scintillation counter methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
Affinity DataKi: 0.140nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Displacement of [3H]citalopram from rat cortical serotonin transporter (SERT)More data for this Ligand-Target Pair
Affinity DataKi: 0.180nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
Affinity DataKi: 0.180nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO cell membranes incubated for 120 mins by scintillation counter methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 0.190nMAssay Description:Displacement of [3H]paroxetine from 5-HTTMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO cell membranes incubated for 120 mins by scintillation counter methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.230nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataKi: 0.240nMAssay Description:Displacement of [3H]citalopram from Sprague-Dawley rat SERTMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO cell membranes incubated for 120 mins by scintillation counter methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO cell membranes incubated for 120 mins by scintillation counter methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO cell membranes incubated for 120 mins by scintillation counter methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
Affinity DataKi: 0.310nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataKi: 0.320nMAssay Description:Displacement of [3H]citalopram from rat cortical serotonin transporter (SERT)More data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO cell membranes incubated for 120 mins by scintillation counter methodMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataKi: 0.370nMAssay Description:Displacement of [3H]citalopram from rat cortical serotonin transporter (SERT)More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataKi: 0.430nMAssay Description:Displacement of [3H]citalopram from Sprague-Dawley rat SERTMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Displacement of [3H]-LSD from human 5HT6 receptor expressed in CHO cells assessed as inhibition constant incubated for 120 mins by liquid scintillati...More data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO cell membranes incubated for 120 mins by scintillation counter methodMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataKi: 0.430nMAssay Description:Displacement of [3H]citalopram from Sprague-Dawley rat SERTMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:32 μg membrane proteins of CHO cell expressing human 5-HT6 receptor, 2 nM of radioactive marker [3H]LSD, a compound of the present invention hav...More data for this Ligand-Target Pair
Affinity DataKi: 0.460nMAssay Description:32 μg membrane proteins of CHO cell expressing human 5-HT6 receptor, 2 nM of radioactive marker [3H]LSD, a compound of the present invention hav...More data for this Ligand-Target Pair
Affinity DataKi: 0.460nMAssay Description:Displacement of [3H]-LSD from human 5HT6 receptor expressed in CHO cells assessed as inhibition constant incubated for 120 mins by liquid scintillati...More data for this Ligand-Target Pair
Affinity DataKi: 0.460nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO cell membranes incubated for 120 mins by scintillation counter methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.480nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:32 μg membrane proteins of CHO cell expressing human 5-HT6 receptor, 2 nM of radioactive marker [3H]LSD, a compound of the present invention hav...More data for this Ligand-Target Pair
Affinity DataKi: 0.510nMAssay Description:Displacement of [3H]-LSD from human 5HT6 receptor expressed in CHO cells assessed as inhibition constant incubated for 120 mins by liquid scintillati...More data for this Ligand-Target Pair
Affinity DataKi: 0.520nMAssay Description:32 μg membrane proteins of CHO cell expressing human 5-HT6 receptor, 2 nM of radioactive marker [3H]LSD, a compound of the present invention hav...More data for this Ligand-Target Pair
Affinity DataKi: 0.520nMAssay Description:Displacement of [3H]-LSD from human 5HT6 receptor expressed in CHO cells assessed as inhibition constant incubated for 120 mins by liquid scintillati...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataKi: 0.530nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataKi: 0.530nMAssay Description:Displacement of [3H]citalopram from rat cortical serotonin transporter (SERT)More data for this Ligand-Target Pair
Affinity DataKi: 0.550nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO cell membranes incubated for 120 mins by scintillation counter methodMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]paroxetine from 5-HTTMore data for this Ligand-Target Pair
Affinity DataKi: 0.610nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
Affinity DataKi: 0.640nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO cell membranes incubated for 120 mins by scintillation counter methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.650nMAssay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
Affinity DataKi: 0.670nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO cell membranes incubated for 120 mins by scintillation counter methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.680nMAssay Description:Displacement of [3H]-LSD from human 5HT6 receptor expressed in CHO cells assessed as inhibition constant incubated for 120 mins by liquid scintillati...More data for this Ligand-Target Pair
Affinity DataKi: 0.680nMAssay Description:32 μg membrane proteins of CHO cell expressing human 5-HT6 receptor, 2 nM of radioactive marker [3H]LSD, a compound of the present invention hav...More data for this Ligand-Target Pair