Affinity DataKi: 0.0290nMAssay Description:Binding affinity against Rat 5-hydroxytryptamine 7 receptor using [3H]-5-HTMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.0640nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.110nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.140nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.140nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.160nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.160nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Displacement of [3H]-quinpirole from Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Displacement of [3H]-quinpirole from human dopamine D2A receptors expressed in LtK cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.160nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.200nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.220nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Affinity DataKi: 0.230nMAssay Description:In vitro binding affinity at rat liver Angiotensin II receptor, type 1 was determined based on displacement of [125I]-Ang IIMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.230nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.230nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Affinity DataKi: 0.246nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Displacement of [3H]-raclopride from Dopamine receptor D3More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.280nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.290nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.320nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.330nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.340nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.350nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.380nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.420nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.430nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.440nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Affinity DataKi: 0.440nMAssay Description:Displacement of [3H]-raclopride from human dopamine D2A receptors expressed in LtK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Ability to displace [3H]-8-OH-DPAT binding to rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:In vitro affinity at 5-hydroxytryptamine 1A receptor of rat hippocampus by [3H]-8-OH-DPAT displacement.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.460nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.520nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.550nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.560nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.590nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.640nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Affinity DataKi: 0.660nMAssay Description:Inhibition of [3H]-raclopride binding to Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.700nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Affinity DataKi: 0.75nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease (isolated domain)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.780nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.850nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Affinity DataKi: 0.870nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to rat 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.880nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.890nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.910nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.910nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 0.990nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Cricetulus griseus (Chinese hamster) (Cricetulus b...)
Acturum Life Science
US Patent
Acturum Life Science
US Patent
Affinity DataKi: 1nMpH: 7.4Assay Description:Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...More data for this Ligand-Target Pair