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Found 1020 with Last Name = 'kadow' and Initial = 'jf'
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM13934(Atazanavir | BMS 232632 | CGP 73547 | CHEMBL1163 |...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307542(5-(3-((2-(1,2,4-Oxadiazol-3-yl)propan-2-yl)carbamo...)
Affinity DataIC50:  0.603nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307547(BDBM307549 | N-(2-(1,2,4-oxadiazol-3-yl)propan-2-y...)
Affinity DataIC50:  1.52nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307550(N-(2-cyanopropan-2-yl)-5-(6-ethoxy-2-(4-fluorophen...)
Affinity DataIC50:  1.84nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307545(6-Ethoxy-2-(4-fluorophenyl)-5-(4-methoxy-3-((1-(py...)
Affinity DataIC50:  1.89nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307566(5-(3-((2-(1,2,4-thiadiazol-3-yl)propan-2-yl)carbam...)
Affinity DataIC50:  2.04nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307561(5-(3-((2-cyanopropan-2-yl)carbamoyl)-4-(methoxy-d3...)
Affinity DataIC50:  2.04nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM149222(US8962651, 4)
Affinity DataIC50:  2.05nMpH: 7.5 T: 2°CAssay Description:An on-bead solid phase homogeneous assay was used in a 384-well format to assess NS5B inhibitors (WangY-K, Rigat K, Roberts S, and Gao M (2006) Anal ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307542(5-(3-((2-(1,2,4-Oxadiazol-3-yl)propan-2-yl)carbamo...)
Affinity DataIC50:  2.22nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM149221(US8962651, 1)
Affinity DataIC50:  2.32nMpH: 7.5 T: 2°CAssay Description:An on-bead solid phase homogeneous assay was used in a 384-well format to assess NS5B inhibitors (WangY-K, Rigat K, Roberts S, and Gao M (2006) Anal ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM47174(US8962651, 17)
Affinity DataIC50:  2.40nMpH: 7.5 T: 2°CAssay Description:An on-bead solid phase homogeneous assay was used in a 384-well format to assess NS5B inhibitors (WangY-K, Rigat K, Roberts S, and Gao M (2006) Anal ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307558(5-(3-((2-(1,2,4-oxadiazol-3-yl)propan-2-yl)carbamo...)
Affinity DataIC50:  2.48nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307548(N-(bicyclo[1.1.1]pentan-1-yl)-5-(6-ethoxy-2-(4-flu...)
Affinity DataIC50:  2.48nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307546(5-(6-Ethoxy-2-(4-fluorophenyl)-3-(methylcarbamoyl)...)
Affinity DataIC50:  2.72nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307547(BDBM307549 | N-(2-(1,2,4-oxadiazol-3-yl)propan-2-y...)
Affinity DataIC50:  2.73nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307551(5-(3-((2-(1,2,4-oxadiazol-3-yl)propan-2-yl)carbamo...)
Affinity DataIC50:  2.83nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM149225(US8962651, 9)
Affinity DataIC50:  2.87nMpH: 7.5 T: 2°CAssay Description:An on-bead solid phase homogeneous assay was used in a 384-well format to assess NS5B inhibitors (WangY-K, Rigat K, Roberts S, and Gao M (2006) Anal ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307562(5-(2-(4-Fluorophenyl)-3-(methylcarbamoyl)-6-(2,2,2...)
Affinity DataIC50:  2.95nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307543(5-(3-((2-Cyanopropan-2-yl)carbamoyl)phenyl)-2-(4-f...)
Affinity DataIC50:  3.02nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307539(5-(3-((2-(1,2,4-Oxadiazol-3-yl)propan-2-yl)carbamo...)
Affinity DataIC50:  3.31nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM149227(US8962651, 13)
Affinity DataIC50:  3.42nMpH: 7.5 T: 2°CAssay Description:An on-bead solid phase homogeneous assay was used in a 384-well format to assess NS5B inhibitors (WangY-K, Rigat K, Roberts S, and Gao M (2006) Anal ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307537(5-(3-(Bicyclo[1.1.1]pentan-1-ylcarbamoyl)-4-fluoro...)
Affinity DataIC50:  3.88nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307567(5-(3-((2-(1,2,4-Oxadiazol-3-yl)propan-2-yl)carbamo...)
Affinity DataIC50:  3.89nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523567(CHEMBL4522729)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523568(CHEMBL4447493)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523559(CHEMBL4573907)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523569(CHEMBL4463796)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523558(CHEMBL4460401)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523560(CHEMBL4300203)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523561(CHEMBL4437104)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523562(CHEMBL4474072)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523563(CHEMBL4554438)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523564(CHEMBL4525849)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523565(CHEMBL4542773)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523566(CHEMBL4574382)
Affinity DataIC50:  4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM149223(US8962651, 7)
Affinity DataIC50:  4.13nMpH: 7.5 T: 2°CAssay Description:An on-bead solid phase homogeneous assay was used in a 384-well format to assess NS5B inhibitors (WangY-K, Rigat K, Roberts S, and Gao M (2006) Anal ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307535(2-(4-Fluorophenyl)-5-(4-methoxy-3-((1-(pyrimidin-2...)
Affinity DataIC50:  4.15nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)TBA
LigandPNGBDBM9273((3S)-oxolan-3-yl N-[(2S,3R)-3-hydroxy-4-[(4-methox...)
Affinity DataIC50:  4.20nMMore data for this Ligand-Target Pair
In DepthDetails
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307552(5-(3-((2-(1,2,4-Oxadiazol-3-yl)propan-2-yl)carbamo...)
Affinity DataIC50:  4.20nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307538(5-(3-(Bicyclo[1.1.1]pentan-1-ylcarbamoyl)phenyl)-6...)
Affinity DataIC50:  4.30nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307536(5-(4-Fluoro-3-((1-(pyrimidin-2-yl)cyclopropyl)carb...)
Affinity DataIC50:  4.38nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307554(5-(3-((2-(1,2,4-oxadiazol-3-yl)propan-2-yl)carbamo...)
Affinity DataIC50:  4.49nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307553(6-(2,2-difluoroethoxy)-2-(4-fluorophenyl)-N-methyl...)
Affinity DataIC50:  4.54nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM149224(US8962651, 8)
Affinity DataIC50:  4.80nMpH: 7.5 T: 2°CAssay Description:An on-bead solid phase homogeneous assay was used in a 384-well format to assess NS5B inhibitors (WangY-K, Rigat K, Roberts S, and Gao M (2006) Anal ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307541(5-(3-((1-Cyanocyclopropyl)carbamoyl)phenyl)-2-(4-f...)
Affinity DataIC50:  4.97nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307539(5-(3-((2-(1,2,4-Oxadiazol-3-yl)propan-2-yl)carbamo...)
Affinity DataIC50:  5.05nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307540(6-Ethoxy-2-(4-fluorophenyl)-N-methyl-5-(3-((1-(pyr...)
Affinity DataIC50:  5.78nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM100761(US8507683, 12)
Affinity DataIC50:  6nMAssay Description:HCV NS5B enzyme assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307565(5-(3-((2-(3H-imidazo[4,5-c]pyridin-2-yl)propan-2-y...)
Affinity DataIC50:  6.01nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307556(5-(3-((2-(1,2,4-Oxadiazol-3-yl)propan-2-yl)carbamo...)
Affinity DataIC50:  7.14nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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