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Found 72 with Last Name = 'kajino' and Initial = 'm'
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM394383(N-methyl-1-[1-(phenylsulfonyl)-5-(3-thienyl)-1H-py...)
Affinity DataIC50:  4.20nMAssay Description:According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038923(1-[4-(2-Chloro-phenyl)-6,7-dimethyl-quinolin-3-yl]...)
Affinity DataIC50:  5.80nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376111(CHEMBL258618)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376119(CHEMBL259484)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376115(CHEMBL437107)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376123(CHEMBL260064)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376122(CHEMBL260065)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376118(CHEMBL258705)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038906(1-[8-Chloro-4-(2-chloro-phenyl)-6-methyl-quinolin-...)
Affinity DataIC50:  8.90nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM394395(1-[5-(2,4-Difluorophenyl)-1-(pyridin-3-ylsulfonyl)...)
Affinity DataIC50:  8.90nMAssay Description:According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM394391(1-{5-(2-Fluorophenyl)-1-[(2-fluorophenyl)sulfonyl]...)
Affinity DataIC50:  9nMAssay Description:According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038918(1-[4-(2-Chloro-phenyl)-6,8-dimethyl-quinolin-3-yl]...)
Affinity DataIC50:  9.20nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038900(1-(7-Chloro-6-methyl-4-o-tolyl-quinolin-3-yl)-3-(2...)
Affinity DataIC50:  9.30nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376114(CHEMBL259720)
Affinity DataIC50:  9.40nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376120(CHEMBL259554)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376125(CHEMBL411083)
Affinity DataIC50:  10nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376110(CHEMBL409350)
Affinity DataIC50:  10nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376124(CHEMBL261413)
Affinity DataIC50:  10nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376113(CHEMBL258631)
Affinity DataIC50:  11nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376112(CHEMBL258845)
Affinity DataIC50:  11nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038920(1-[6-Chloro-4-(2-chloro-phenyl)-8-methyl-quinolin-...)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038922(1-(2,4-Difluoro-phenyl)-3-(6,8-dimethyl-4-o-tolyl-...)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM394389(Ethyl 1-(pyridazin-3-ylsulfonyl)-5-phenyl-1H-pyrro...)
Affinity DataIC50:  13nMAssay Description:According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038919(1-[4-(2-Chloro-phenyl)-6-ethyl-quinolin-3-yl]-3-(2...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038905(1-[4-(2-Chloro-phenyl)-6-isopropyl-quinolin-3-yl]-...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038915(1-[4-(2-Chloro-phenyl)-6,8-dimethyl-quinolin-3-yl]...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038912(1-[4-(2-Chloro-phenyl)-6-methyl-quinolin-3-yl]-3-(...)
Affinity DataIC50:  16.8nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038901(1-[6-Chloro-4-(2-chloro-phenyl)-quinolin-3-yl]-3-(...)
Affinity DataIC50:  21.2nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038907(1-(2,4-Difluoro-phenyl)-3-(6-methyl-4-o-tolyl-quin...)
Affinity DataIC50:  21.7nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM394392(1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-...)
Affinity DataIC50:  22nMAssay Description:According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...More data for this Ligand-Target Pair
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038916(1-[6-Chloro-4-(2-methoxy-phenyl)-quinolin-3-yl]-3-...)
Affinity DataIC50:  24nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376121(CHEMBL259555)
Affinity DataIC50:  28nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038914(1-[4-(2-Chloro-phenyl)-6,8-dimethyl-quinolin-3-yl]...)
Affinity DataIC50:  28nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038909(1-(6-Chloro-4-o-tolyl-quinolin-3-yl)-3-(2,4-difluo...)
Affinity DataIC50:  28.7nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373215(CHEMBL259060)
Affinity DataIC50:  30nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373215(CHEMBL259060)
Affinity DataIC50:  30nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373215(CHEMBL259060)
Affinity DataIC50:  30nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376116(CHEMBL427561)
Affinity DataIC50:  33nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM394388(1-[1-(1-Benzothien-2-ylsulfonyl)-5-phenyl-1H-pyrro...)
Affinity DataIC50:  33nMAssay Description:According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM394394(N-Methyl-1-[5-(2-methylphenyl)-1-(pyridin-3-ylsulf...)
Affinity DataIC50:  36nMAssay Description:According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376117(CHEMBL406408)
Affinity DataIC50:  43nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM394378(Ethyl 1-[(4-methoxyphenyl)sulfonyl]-5-phenyl-1H-py...)
Affinity DataIC50:  51nMAssay Description:According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM394386(N-Methyl-1-[5-phenyl-1-(3-thienylsulfonyl)-1H-pyrr...)
Affinity DataIC50:  51nMAssay Description:According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM394390(1-[5-(2-Fluorophenyl)-1-{[3-(methylsulfonyl)phenyl...)
Affinity DataIC50:  62nMAssay Description:According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM394387(US10308605, Example 140)
Affinity DataIC50:  78nMAssay Description:According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM394393(N-Methyl-3-({4-[(methylamino)methyl]-2-phenyl-1H-p...)
Affinity DataIC50:  86nMAssay Description:According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038913(1-[6-Chloro-4-(3-chloro-phenyl)-quinolin-3-yl]-3-(...)
Affinity DataIC50:  90.6nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM394377(N-Methyl-1-{5-(3-methylphenyl)-1-[(4-methylphenyl)...)
Affinity DataIC50:  91nMAssay Description:According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038917(1-[6-Chloro-4-(4-methoxy-phenyl)-quinolin-3-yl]-3-...)
Affinity DataIC50:  121nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038908(1-[4-(2-Chloro-phenyl)-quinolin-3-yl]-3-(2,4-diflu...)
Affinity DataIC50:  125nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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