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Found 304 with Last Name = 'kalin' and Initial = 'jh'
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM113742(N-[4-(2-Hydrazinylethyl)phenyl]-4-phenylbutanamide...)
Affinity DataKi:  59nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM113750((2E)-N-[4-(2-Hydrazinylethyl)phenyl]-3-phenylprop-...)
Affinity DataKi:  100nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM113753(N-[4-(2-Hydrazinylethyl)phenyl]-4-(1H-indol-3-yl)b...)
Affinity DataKi:  100nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM113745(4-(4-Fluorophenyl)-N-[4-(2-hydrazinylethyl)phenyl]...)
Affinity DataKi:  138nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM113744(4-(4-Chlorophenyl)-N-[4-(2-hydrazinylethyl)phenyl]...)
Affinity DataKi:  156nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM113748(2-(3-{[4-(2-Hydrazinylethyl)phenyl]amino}-3-oxopro...)
Affinity DataKi:  204nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM113746(N-[4-(2-Hydrazinylethyl)phenyl]-4-(4-methoxyphenyl...)
Affinity DataKi:  207nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM113752(N-[4-(2-Hydrazinylethyl)phenyl]-3-(1H-indol-3-yl)p...)
Affinity DataKi:  210nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM113749(3-(3-{[4-(2-Hydrazinylethyl)phenyl]amino}-3-oxopro...)
Affinity DataKi:  223nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM113741(N-[4-(2-Hydrazinylethyl)phenyl]-3-phenylpropanamid...)
Affinity DataKi:  260nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM113743(N-[4-(2-Hydrazinylethyl)phenyl]-5-phenylpentanamid...)
Affinity DataKi:  260nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM113739(N-[4-(2-Hydrazinylethyl)phenyl]benzamide dihydroch...)
Affinity DataKi:  280nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM113747(N-[4-(2-Hydrazinylethyl)phenyl]-4-(4-nitrophenyl)b...)
Affinity DataKi:  282nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM113740(N-[4-(2-Hydrazinylethyl)phenyl]-2-phenylacetamide ...)
Affinity DataKi:  370nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM50105417(CHEMBL1089 | Nardil | PHENELZINE | Phenethyl-hydra...)
Affinity DataKi:  820nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL MAO-A/B (final concentrations were 100-200 nM and 0.837 µM for MAO-A and MAO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM113751({3-[4-(Benxyloxy)phenyl]propyl}hydrazine dihydroch...)
Affinity DataKi:  900nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM113755(N-Benzyl-N-[4-(2-hydrazinylethyl)phenyl]-4-phenylb...)
Affinity DataKi:  1.60E+3nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM113754(N-[4-(2-Hydrazinylethyl)phenyl]-N-methyl-4-phenylb...)
Affinity DataKi:  2.00E+3nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM113742(N-[4-(2-Hydrazinylethyl)phenyl]-4-phenylbutanamide...)
Affinity DataKi:  2.60E+3nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL MAO-A/B (final concentrations were 100-200 nM and 0.837 µM for MAO-A and MAO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM50105417(CHEMBL1089 | Nardil | PHENELZINE | Phenethyl-hydra...)
Affinity DataKi:  3.90E+3nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL MAO-A/B (final concentrations were 100-200 nM and 0.837 µM for MAO-A and MAO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM113730((3-Phenylpropyl)hydrazine dihydrochloride salt (9c...)
Affinity DataKi:  5.00E+3nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM50105417(CHEMBL1089 | Nardil | PHENELZINE | Phenethyl-hydra...)
Affinity DataKi:  5.60E+3nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM113742(N-[4-(2-Hydrazinylethyl)phenyl]-4-phenylbutanamide...)
Affinity DataKi:  6.50E+3nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL MAO-A/B (final concentrations were 100-200 nM and 0.837 µM for MAO-A and MAO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM113732([3-(4-Methoxyphenyl)propyl]hydrazine dihydrochlori...)
Affinity DataKi:  8.00E+3nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM113737((3-Phenoxypropyl)hydrazine dihydrochloride salt (1...)
Affinity DataKi:  1.20E+4nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM113735((4-Phenylbutyl)hydrazine dihydrochloride salt (9h))
Affinity DataKi:  2.20E+4nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM113736((2-Phenoxyethyl)hydrazine dihydrochloride salt (10...)
Affinity DataKi:  4.40E+4nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM218187(US9249087, 30)
Affinity DataIC50:  0.170nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM50380385(CHEMBL2018447)
Affinity DataIC50:  0.459nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM50380391(CHEMBL2018446)
Affinity DataIC50:  0.582nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM50380400(CHEMBL2018301)
Affinity DataIC50:  0.704nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM50380390(CHEMBL2018448)
Affinity DataIC50:  0.799nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM50380386(CHEMBL2018452)
Affinity DataIC50:  0.872nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM50380384(CHEMBL2018442)
Affinity DataIC50:  0.972nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM50380401(CHEMBL2018300)
Affinity DataIC50:  1.02nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM50380387(CHEMBL2018451)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM124188(US8748451, 3 | US8748451, 7)
Affinity DataIC50:  1.40nMpH: 8.0 T: 2°CAssay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM50380394(CHEMBL2018443)
Affinity DataIC50:  1.44nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM218178(US9249087, 21)
Affinity DataIC50:  1.46nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM218227(US9249087, Table 1 , Compound 4)
Affinity DataIC50:  1.46nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50439673(CHEMBL2417782)
Affinity DataIC50:  2nMAssay Description:Inhibition of His-6-tagged full length HDAC3 (unknown origin) expressed in sf9 cells and co-expressed in SMRT gene (395 to 489) using carboxyfluoresc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM50380398(CHEMBL2018303)
Affinity DataIC50:  2.25nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM50380388(CHEMBL2018450)
Affinity DataIC50:  2.49nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM218161(US9249087, 4)
Affinity DataIC50:  2.51nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM218225(US9249087, Table 1 , Compound 2)
Affinity DataIC50:  2.51nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM218174(US9249087, 17)
Affinity DataIC50:  2.94nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM218230(US9249087, Table 1 , Compound 7)
Affinity DataIC50:  2.94nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM50380393(CHEMBL2018444)
Affinity DataIC50:  2.96nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM50380396(CHEMBL2018305)
Affinity DataIC50:  2.99nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM50380392(CHEMBL2018445)
Affinity DataIC50:  3.05nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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