Found 1059 with Last Name = 'kargbo' and Initial = 'rb' 
Affinity DataKi: 130nMAssay Description:Binding affinity to CBRN (unknown origin) incubated for 60 mins by lenalidomide displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 440nMAssay Description:Binding affinity to CBRN (unknown origin) incubated for 60 mins by lenalidomide displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 800nMAssay Description:Binding affinity to CBRN (unknown origin) incubated for 60 mins by lenalidomide displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 970nMAssay Description:Binding affinity to CBRN (unknown origin) incubated for 60 mins by lenalidomide displacement assayMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Usona Institute
Curated by ChEMBL
Usona Institute
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin)More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Usona Institute
Curated by ChEMBL
Usona Institute
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Usona Institute
Curated by ChEMBL
Usona Institute
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Usona Institute
Curated by ChEMBL
Usona Institute
Curated by ChEMBL
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Usona Institute
Curated by ChEMBL
Usona Institute
Curated by ChEMBL
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Usona Institute
Curated by ChEMBL
Usona Institute
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Usona Institute
Curated by ChEMBL
Usona Institute
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin)More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Usona Institute
Curated by ChEMBL
Usona Institute
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Usona Institute
Curated by ChEMBL
Usona Institute
Curated by ChEMBL
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Usona Institute
Curated by ChEMBL
Usona Institute
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.49E+3nMAssay Description:Binding affinity to CBRN (unknown origin) incubated for 60 mins by lenalidomide displacement assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 2.20E+3nMAssay Description:Binding affinity to CBRN (unknown origin) incubated for 60 mins by lenalidomide displacement assayMore data for this Ligand-Target Pair
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Usona Institute
Curated by ChEMBL
Usona Institute
Curated by ChEMBL
Affinity DataIC50: 0.00200nMAssay Description:Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
Affinity DataIC50: 0.00280nMAssay Description:Inhibition of ACSS2 in human MDA-MB-468 cells assessed as 13C-acetate incorporation incubated for 5 hrs measured under hypoxic conditions by LCMS ana...More data for this Ligand-Target Pair
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Usona Institute
Curated by ChEMBL
Usona Institute
Curated by ChEMBL
Affinity DataIC50: 0.00300nMAssay Description:Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Usona Institute
Curated by ChEMBL
Usona Institute
Curated by ChEMBL
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Usona Institute
Curated by ChEMBL
Usona Institute
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Displacement of Cy5-labelled tracer from biotinylated GDP-loaded human recombinant KRAS G12D mutant (1 to 169 residues) measured after 60 mins by TR-...More data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Modulation of human 5HT2C expressed in HEK293T cells co-transfected with Galphaq-RLuc8, Ggamma1-GFP2 and Gbeta1 assessed as dissociation of Galphaq f...More data for this Ligand-Target Pair
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Usona Institute
Curated by ChEMBL
Usona Institute
Curated by ChEMBL
Affinity DataIC50: 0.160nMAssay Description:Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Usona Institute
Curated by ChEMBL
Usona Institute
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Usona Institute
Curated by ChEMBL
Usona Institute
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Displacement of Cy5-labelled tracer from biotinylated GDP-loaded human recombinant KRAS G12D mutant (1 to 169 residues) measured after 60 mins by TR-...More data for this Ligand-Target Pair
Affinity DataIC50: 0.245nMAssay Description:Modulation of human 5HT2B expressed in HEK293T cells co-transfected with Galphaq-RLuc8, Ggamma1-GFP2 and Gbeta1 assessed as dissociation of Galphaq f...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of ERalpha in human T47D cells by ERE-driven luciferase reporter gene assay based target engagement assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Displacement of Cy5-labelled tracer from biotinylated GDP-loaded human recombinant KRAS G12D mutant (1 to 169 residues) measured after 60 mins by TR-...More data for this Ligand-Target Pair
Affinity DataIC50: 0.330nMAssay Description:Inhibition of ACSS2 in human MDA-MB-468 cells assessed as 13C-acetate incorporation incubated for 5 hrs measured under hypoxic conditions by LCMS ana...More data for this Ligand-Target Pair
Affinity DataIC50: 0.370nMAssay Description:Inhibition of ERalpha in human T47D cells by ERE-driven luciferase reporter gene assay based target engagement assayMore data for this Ligand-Target Pair
TargetLymphokine-activated killer T-cell-originated protein kinase(Homo sapiens (Human))
Oncotherapy Science
US Patent
Oncotherapy Science
US Patent
Affinity DataIC50: 0.380nMpH: 7.4 T: 2°CAssay Description:PBK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a s...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Displacement of Cy5-labelled tracer from biotinylated GDP-loaded human recombinant KRAS G12D mutant (1 to 169 residues) measured after 60 mins by TR-...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Displacement of Cy5-labelled tracer from biotinylated GDP-loaded human recombinant KRAS G12D mutant (1 to 169 residues) measured after 60 mins by TR-...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Displacement of Cy5-labelled tracer from biotinylated GDP-loaded human recombinant KRAS G12D mutant (1 to 169 residues) measured after 60 mins by TR-...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Induction of ERalpha protein degradation in human MCF7 cells assessed as reduction in ERalpha protein levels incubated for 24 hrs by In-cell western ...More data for this Ligand-Target Pair
TargetLymphokine-activated killer T-cell-originated protein kinase(Homo sapiens (Human))
Oncotherapy Science
US Patent
Oncotherapy Science
US Patent
Affinity DataIC50: 0.430nMpH: 7.4 T: 2°CAssay Description:PBK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a s...More data for this Ligand-Target Pair
Affinity DataIC50: 0.463nMAssay Description:Inhibition of ACSS2 in human MDA-MB-468 cells assessed as 13C-acetate incorporation incubated for 5 hrs measured under hypoxic conditions by LCMS ana...More data for this Ligand-Target Pair
Affinity DataIC50: 0.490nMAssay Description:Inhibition of ERalpha in human T47D cells by ERE-driven luciferase reporter gene assay based target engagement assayMore data for this Ligand-Target Pair
